Small molecules that target group II introns are potent antifungal agents

Phantom PAINS: Problems with the Utility of Alerts for Pan-Assay INterference CompoundS

(2017) Stephen J. Capuzzi et al.   Journal of Chemical Information and Modeling

How Frequently Are Pan-Assay Interference Compounds Active? Large-Scale Analysis of Screening Data Reveals Diverse Activity Profiles, Low Global Hit Frequency, and Many Consistently Inactive Compounds

(2017) Swarit Jasial et al.   JOURNAL OF MEDICINAL CHEMISTRY

Small Molecule Inhibition of microRNA-210 Reprograms an Oncogenic Hypoxic Circuit

(2017) Matthew G. Costales et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The SMAD3 transcription factor binds complex RNA structures with high affinity

(2017) Thayne H. Dickey et al.   NUCLEIC ACIDS RESEARCH

Structural Insights into the Mechanism of Group II Intron Splicing

(2017) Chen Zhao et al.   TRENDS IN BIOCHEMICAL SCIENCES

Amiloride as a new RNA-binding scaffold with activity against HIV-1 TAR

(2017) Neeraj N. Patwardhan et al.   MedChemComm

Modulation of the E. coli rpoH Temperature Sensor with Triptycene-Based Small Molecules

(2016) Stephanie A. Barros et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Small Molecule-Based Pattern Recognition To Classify RNA Structure

(2016) Christopher S. Eubanks et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Design of a small molecule against an oncogenic noncoding RNA

(2016) Sai Pradeep Velagapudi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Atomic resolution mechanistic studies of ribocil: A highly selective unnatural ligand mimic of theE. coliFMN riboswitch

(2016) John A. Howe et al.   RNA Biology

Novel Riboswitch-Binding Flavin Analog That Protects Mice against Clostridium difficile Infection without Inhibiting Cecal Flora

(2015) Kenneth F. Blount et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Selective small-molecule inhibition of an RNA structural element

(2015) John A. Howe et al.   NATURE

RNA Structures as Mediators of Neurological Diseases and as Drug Targets

(2015) Viachaslau Bernat et al.   NEURON

High-Throughput Platform Assay Technology for the Discovery of pre-microRNA-Selective Small Molecule Probes

(2014) Daniel A. Lorenz et al.   BIOCONJUGATE CHEMISTRY

Global trends in the distribution of Candida species causing candidemia

(2014) J. Guinea   CLINICAL MICROBIOLOGY AND INFECTION

Identification of Biologically Active, HIV TAR RNA-Binding Small Molecules Using Small Molecule Microarrays

(2014) Joanna Sztuba-Solinska et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Chemistry: Chemical con artists foil drug discovery

(2014) Jonathan Baell et al.   NATURE

Principles of ion recognition in RNA: insights from the group II intron structures

(2014) M. Marcia et al.   RNA

Hepatitis C Virus Translation Inhibitors Targeting the Internal Ribosomal Entry Site

(2013) Sergey M. Dibrov et al.   JOURNAL OF MEDICINAL CHEMISTRY

Ribosome-targeting antibiotics and mechanisms of bacterial resistance

(2013) Daniel N. Wilson   NATURE REVIEWS MICROBIOLOGY

Control of Candida albicans Metabolism and Biofilm Formation by Pseudomonas aeruginosa Phenazines

(2013) D. K. Morales et al.   mBio

Elements of ribosomal drug resistance and specificity

(2012) Gregor M Blaha et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Recurrent insertion of 5'-terminal nucleotides and loss of the branchpoint motif in lineages of group II introns inserted in mitochondrial preribosomal RNAs

(2011) C.-F. Li et al.   RNA

Candida bloodstream infections in intensive care units: Analysis of the extended prevalence of infection in intensive care unit study*

(2010) Daniel H. Kett et al.   CRITICAL CARE MEDICINE

Dual roles for the Mss116 cofactor during splicing of the ai5γ group II intron

(2010) Nora Zingler et al.   NUCLEIC ACIDS RESEARCH

Novel Riboswitch Ligand Analogs as Selective Inhibitors of Guanine-Related Metabolic Pathways

(2010) Jérôme Mulhbacher et al.   PLoS Pathogens

Design and Antimicrobial Action of Purine Analogues That Bind Guanine Riboswitches

(2009) Jane N. Kim et al.   ACS Chemical Biology

Liposomal Amphotericin B

(2009) Marit D. Moen et al.   DRUGS

Correlation between Biofilm Formation and the Hypoxic Response inCandida parapsilosis

(2009) Tristan Rossignol et al.   EUKARYOTIC CELL