标题
Amiloride as a new RNA-binding scaffold with activity against HIV-1 TAR
作者
关键词
-
出版物
MedChemComm
Volume 8, Issue 5, Pages 1022-1036
出版商
Royal Society of Chemistry (RSC)
发表日期
2017-03-15
DOI
10.1039/c6md00729e
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Inforna 2.0: A Platform for the Sequence-Based Design of Small Molecules Targeting Structured RNAs
- (2016) Matthew D. Disney et al. ACS Chemical Biology
- An Evolved RNA Recognition Motif That Suppresses HIV-1 Tat/TAR-Dependent Transcription
- (2016) David W. Crawford et al. ACS Chemical Biology
- Development of Small Molecules with a Noncanonical Binding Mode to HIV-1 Trans Activation Response (TAR) RNA
- (2016) Fardokht A. Abulwerdi et al. JOURNAL OF MEDICINAL CHEMISTRY
- Small Molecule-Based Pattern Recognition To Classify RNA Structure
- (2016) Christopher S. Eubanks et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Multivalency in the recognition and antagonism of a HIV TAR RNA–TAT assembly using an aminoglycoside benzimidazole scaffold
- (2016) Sunil Kumar et al. ORGANIC & BIOMOLECULAR CHEMISTRY
- Design of a bioactive small molecule that targets r(AUUCU) repeats in spinocerebellar ataxia 10
- (2016) Wang-Yong Yang et al. Nature Communications
- Small molecules targeting viral RNA
- (2016) Thomas Hermann Wiley Interdisciplinary Reviews-RNA
- Small Molecule Microarrays Enable the Identification of a Selective, Quadruplex-Binding Inhibitor of MYC Expression
- (2015) Kenneth M. Felsenstein et al. ACS Chemical Biology
- A Cyclic Mimic of HIV Tat Differentiates Similar TAR RNAs on the Basis of Distinct Dynamic Behaviors
- (2015) Jia Lu et al. BIOCHEMISTRY
- Cheminformatic comparison of approved drugs from natural product versus synthetic origins
- (2015) Christopher F. Stratton et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Production of new amilorides as potent inhibitors of mitochondrial respiratory complex I
- (2015) Masatoshi Murai et al. BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY
- Structure based approaches for targeting non-coding RNAs with small molecules
- (2015) Matthew D Shortridge et al. CURRENT OPINION IN STRUCTURAL BIOLOGY
- Rationally Designed Small Molecules That Target Both the DNA and RNA Causing Myotonic Dystrophy Type 1
- (2015) Lien Nguyen et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Selective small-molecule inhibition of an RNA structural element
- (2015) John A. Howe et al. NATURE
- SMN2 splice modulators enhance U1–pre-mRNA association and rescue SMA mice
- (2015) James Palacino et al. Nature Chemical Biology
- Fragment based search for small molecule inhibitors of HIV-1 Tat-TAR
- (2014) Mirco Zeiger et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- The Noncoding RNA Revolution—Trashing Old Rules to Forge New Ones
- (2014) Thomas R. Cech et al. CELL
- The Design of RNA Binders: Targeting the HIV Replication Cycle as a Case Study
- (2014) Aurélie Blond et al. ChemMedChem
- Development and application of aromatic [13C, 1H] SOFAST-HMQC NMR experiment for nucleic acids
- (2014) Bharathwaj Sathyamoorthy et al. JOURNAL OF BIOMOLECULAR NMR
- Identification of Biologically Active, HIV TAR RNA-Binding Small Molecules Using Small Molecule Microarrays
- (2014) Joanna Sztuba-Solinska et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Sequence-based design of bioactive small molecules that target precursor microRNAs
- (2014) Sai Pradeep Velagapudi et al. Nature Chemical Biology
- SMN2 splicing modifiers improve motor function and longevity in mice with spinal muscular atrophy
- (2014) N. A. Naryshkin et al. SCIENCE
- Targeting RNA–Protein Interactions within the Human Immunodeficiency Virus Type 1 Lifecycle
- (2013) Neil M. Bell et al. BIOCHEMISTRY
- Recognition of HIV-TAR RNA using neomycin–benzimidazole conjugates
- (2013) Nihar Ranjan et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Molecular Similarity in Medicinal Chemistry
- (2013) Gerald Maggiora et al. JOURNAL OF MEDICINAL CHEMISTRY
- A General Method for Constructing Atomic-Resolution RNA Ensembles using NMR Residual Dipolar Couplings: The Basis for Interhelical Motions Revealed
- (2013) Loïc Salmon et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Methods to enable the design of bioactive small molecules targeting RNA
- (2013) Matthew D. Disney et al. ORGANIC & BIOMOLECULAR CHEMISTRY
- RNA-Mediated Regulation in Pathogenic Bacteria
- (2013) I. Caldelari et al. Cold Spring Harbor Perspectives in Medicine
- Rationally Designed Small Molecules Targeting the RNA That Causes Myotonic Dystrophy Type 1 Are Potently Bioactive
- (2012) Jessica L. Childs-Disney et al. ACS Chemical Biology
- Probing a 2-Aminobenzimidazole Library for Binding to RNA Internal Loops via Two-Dimensional Combinatorial Screening
- (2012) Sai Pradeep Velagapudi et al. ACS Chemical Biology
- 2-Amidino analogs of glycine–amiloride conjugates: Inhibitors of urokinase-type plasminogen activator
- (2012) Archna P. Massey et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Toward Targeting RNA Structure: Branched Peptides as Cell-Permeable Ligands to TAR RNA
- (2011) David I. Bryson et al. ACS Chemical Biology
- Recent Advances in Developing Small Molecules Targeting RNA
- (2011) Lirui Guan et al. ACS Chemical Biology
- III. Identification of novel CXCR3 chemokine receptor antagonists with a pyrazinyl–piperazinyl–piperidine scaffold
- (2011) Seong Heon Kim et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Structure–activity studies of RNA-binding oxazolidinone derivatives
- (2011) Iwona Maciagiewicz et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Synthesis and preliminary evaluation of amiloride analogs as inhibitors of the urokinase-type plasminogen activator (uPA)
- (2011) Hayden Matthews et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Recognition of HIV TAR RNA by triazole linked neomycin dimers
- (2011) Sunil Kumar et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Synthesis and Stereospecificity of 4,5-Disubstituted Oxazolidinone Ligands Binding to T-box Riboswitch RNA
- (2011) Crina M. Orac et al. JOURNAL OF MEDICINAL CHEMISTRY
- A Small-Molecule Probe Induces a Conformation in HIV TAR RNA Capable of Binding Drug-Like Fragments
- (2011) Amy Davidson et al. JOURNAL OF MOLECULAR BIOLOGY
- Discovery of selective bioactive small molecules by targeting an RNA dynamic ensemble
- (2011) Andrew C Stelzer et al. Nature Chemical Biology
- New Substructure Filters for Removal of Pan Assay Interference Compounds (PAINS) from Screening Libraries and for Their Exclusion in Bioassays
- (2010) Jonathan B. Baell et al. JOURNAL OF MEDICINAL CHEMISTRY
- Amiloride derived inhibitors of acid-sensing ion channel-3 (ASIC3)
- (2009) Scott D. Kuduk et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Constructing RNA dynamical ensembles by combining MD and motionally decoupled NMR RDCs: new insights into RNA dynamics and adaptive ligand recognition
- (2009) Aaron T. Frank et al. NUCLEIC ACIDS RESEARCH
- Simultaneous recognition of HIV-1 TAR RNA bulge and loop sequences by cyclic peptide mimics of Tat protein
- (2009) A. Davidson et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- 4,5-Disubstituted oxazolidinones: High affinity molecular effectors of RNA function
- (2008) Rajaneesh Anupam et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Characterizing Complex Dynamics in the Transactivation Response Element Apical Loop and Motional Correlations with the Bulge by NMR, Molecular Dynamics, and Mutagenesis
- (2008) Elizabeth A. Dethoff et al. BIOPHYSICAL JOURNAL
- Targeting RNA with Small Molecules
- (2008) Jason R. Thomas et al. CHEMICAL REVIEWS
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