Characterization of apela, a novel endogenous ligand of apelin receptor, in the adult heart

An Apela RNA-Containing Negative Feedback Loop Regulates p53-Mediated Apoptosis in Embryonic Stem Cells

(2015) Mangmang Li et al.   Cell Stem Cell

Molecular Basis of Cardioprotection: Signal Transduction in Ischemic Pre-, Post-, and Remote Conditioning

(2015) G. Heusch   CIRCULATION RESEARCH

Apela Regulates Fluid Homeostasis by Binding to the APJ Receptor to Activate Gi Signaling

(2015) Cheng Deng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Apelin, Elabela/Toddler, and biased agonists as novel therapeutic agents in the cardiovascular system

(2015) Peiran Yang et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Elabela-Apelin Receptor Signaling Pathway is Functional in Mammalian Systems

(2015) Zhi Wang et al.   Scientific Reports

Connective Tissue Growth Factor Inhibition Attenuates Left Ventricular Remodeling and Dysfunction in Pressure Overload–Induced Heart Failure

(2014) Zoltán Szabó et al.   HYPERTENSION

Cardiovascular remodelling in coronary artery disease and heart failure

(2014) Gerd Heusch et al.   LANCET

Apelin Increases Cardiac Contractility via Protein Kinase Cε- and Extracellular Signal-Regulated Kinase-Dependent Mechanisms

(2014) Ábel Perjés et al.   PLoS One

Toddler: An Embryonic Signal That Promotes Cell Movement via Apelin Receptors

(2014) A. Pauli et al.   SCIENCE

Apelin-APJ Signaling Is a Critical Regulator of Endothelial MEF2 Activation in Cardiovascular Development

(2013) Yujung Kang et al.   CIRCULATION RESEARCH

ELABELA: A Hormone Essential for Heart Development Signals via the Apelin Receptor

(2013) Serene C. Chng et al.   DEVELOPMENTAL CELL

p38α regulates SERCA2a function

(2013) Leena Kaikkonen et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Activation of Hypoxia Response in Endothelial Cells Contributes to Ischemic Cardioprotection

(2013) Risto Kerkelä et al.   MOLECULAR AND CELLULAR BIOLOGY

APJ acts as a dual receptor in cardiac hypertrophy

(2012) Maria Cecilia Scimia et al.   NATURE

Physiological regulation of cardiac contractility by endogenous reactive oxygen species

(2011) Á. Perjés et al.   Acta Physiologica

Acute Cardiovascular Effects of Apelin in Humans

(2010) A.G. Japp et al.   CIRCULATION

A Novel and Efficient Model of Coronary Artery Ligation and Myocardial Infarction in the Mouse

(2010) Erhe Gao et al.   CIRCULATION RESEARCH

Extracellular Signal-Regulated Kinases 1 and 2 Regulate the Balance Between Eccentric and Concentric Cardiac Growth

(2010) Izhak Kehat et al.   CIRCULATION RESEARCH

Endogenous regulation of cardiovascular function by apelin-APJ

(2009) David N. Charo et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Apelin decreases myocardial injury and improves right ventricular function in monocrotaline-induced pulmonary hypertension

(2009) Inês Falcão-Pires et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

G Protein-Coupled Receptor APJ and Its Ligand Apelin Act Downstream of Cripto to Specify Embryonic Stem Cells Toward the Cardiac Lineage Through Extracellular Signal-Regulated Kinase/p70S6 Kinase Signaling Pathway

(2009) Cristina D'Aniello et al.   CIRCULATION RESEARCH

Modulation of canine cardiac sodium current by Apelin

(2009) Caroline Chamberland et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Functionally Opposing Roles of Extracellular Signal-Regulated Kinase 1/2 and p38 Mitogen-Activated Protein Kinase in the Regulation of Cardiac Contractility

(2008) István Szokodi et al.   CIRCULATION