Should we target TNF receptors in the intestinal epithelium with glucocorticoids during systemic inflammation?
出版年份 2018 全文链接
标题
Should we target TNF receptors in the intestinal epithelium with glucocorticoids during systemic inflammation?
作者
关键词
-
出版物
EXPERT OPINION ON THERAPEUTIC TARGETS
Volume 22, Issue 12, Pages 1029-1037
出版商
Informa UK Limited
发表日期
2018-10-21
DOI
10.1080/14728222.2018.1539078
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- Simultaneous Inhibition of Tumor Necrosis Factor Receptor 1 and Matrix Metalloproteinase 8 Completely Protects Against Acute Inflammation and Sepsis
- (2018) Sophie Steeland et al. CRITICAL CARE MEDICINE
- Glucocorticoid receptor dimers control intestinal STAT1 and TNF-induced inflammation in mice
- (2018) Marlies Ballegeer et al. JOURNAL OF CLINICAL INVESTIGATION
- Interactions of commensal and pathogenic microorganisms with the intestinal mucosal barrier
- (2018) Eric C. Martens et al. NATURE REVIEWS MICROBIOLOGY
- Dexamethasone Prevents Lipopolysaccharide-Induced Epithelial Barrier Dysfunction in Rat Ileum
- (2018) Aline Barbosa Ribeiro et al. SHOCK
- Therapeutic Mechanisms of Glucocorticoids
- (2018) Jolien Vandewalle et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- AGR2 ameliorates tumor necrosis factor-α-induced epithelial barrier dysfunction via suppression of NF-κB p65-mediated MLCK/p-MLC pathway activation
- (2017) Xiaolin Ye et al. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
- Pathophysiology of the Gut and the Microbiome in the Host Response
- (2017) John D. Lyons et al. Pediatric Critical Care Medicine
- Corticosteroids in Severe Sepsis and Septic Shock
- (2017) Jorge I. F. Salluh et al. SHOCK
- The Gut as the Motor of Multiple Organ Dysfunction in Critical Illness
- (2016) Nathan J. Klingensmith et al. CRITICAL CARE CLINICS
- Nanobodies as therapeutics: big opportunities for small antibodies
- (2016) Sophie Steeland et al. DRUG DISCOVERY TODAY
- Current Understanding of Dysbiosis in Disease in Human and Animal Models
- (2016) Arianna K. DeGruttola et al. INFLAMMATORY BOWEL DISEASES
- Mechanisms of Intestinal Barrier Dysfunction in Sepsis
- (2016) Benyam P. Yoseph et al. SHOCK
- Glucocorticoid‐induced microRNA‐511 protects against TNF by down‐regulating TNFR1
- (2015) Leen Puimège et al. EMBO Molecular Medicine
- β-glucan microparticles targeted to epithelial APN as oral antigen delivery system
- (2015) Kim Baert et al. JOURNAL OF CONTROLLED RELEASE
- Sepsis: a roadmap for future research
- (2015) Jonathan Cohen et al. LANCET INFECTIOUS DISEASES
- Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations
- (2015) Jimmy Z Liu et al. NATURE GENETICS
- Comprehensive Overview of the Structure and Regulation of the Glucocorticoid Receptor
- (2014) Sofie Vandevyver et al. ENDOCRINE REVIEWS
- Caspase-8 controls the gut response to microbial challenges by Tnf-α-dependent and independent pathways
- (2014) Claudia Günther et al. GUT
- Pleiotropic functions of TNF- in the regulation of the intestinal epithelial response to inflammation
- (2014) M. Leppkes et al. INTERNATIONAL IMMUNOLOGY
- Anti-TNF-α therapy for patients with sepsis: a systematic meta-analysis
- (2014) S. Lv et al. INTERNATIONAL JOURNAL OF CLINICAL PRACTICE
- Generation and Characterization of Small Single Domain Antibodies Inhibiting Human Tumor Necrosis Factor Receptor 1
- (2014) Sophie Steeland et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- TNFR1-induced lethal inflammation is mediated by goblet and Paneth cell dysfunction
- (2014) F Van Hauwermeiren et al. Mucosal Immunology
- RIPK1 ensures intestinal homeostasis by protecting the epithelium against apoptosis
- (2014) Nozomi Takahashi et al. NATURE
- Why have clinical trials in sepsis failed?
- (2014) John C. Marshall TRENDS IN MOLECULAR MEDICINE
- Targeting Dexamethasone to Macrophages in a Porcine Endotoxemic Model
- (2013) Asger Granfeldt et al. CRITICAL CARE MEDICINE
- Inhibition of IKKβ in Enterocytes Exacerbates Sepsis-Induced Intestinal Injury and Worsens Mortality
- (2013) Jessica A. Dominguez et al. CRITICAL CARE MEDICINE
- A mouse model of pathological small intestinal epithelial cell apoptosis and shedding induced by systemic administration of lipopolysaccharide
- (2013) J. M. Williams et al. Disease Models & Mechanisms
- Matrix metalloproteinase 13 modulates intestinal epithelial barrier integrity in inflammatory diseases by activating TNF
- (2013) Roosmarijn E. Vandenbroucke et al. EMBO Molecular Medicine
- Safe TNF-based antitumor therapy following p55TNFR reduction in intestinal epithelium
- (2013) Filip Van Hauwermeiren et al. JOURNAL OF CLINICAL INVESTIGATION
- Cytokines in Sepsis: Potent Immunoregulators and Potential Therapeutic Targets—An Updated View
- (2013) Wibke Schulte et al. MEDIATORS OF INFLAMMATION
- Microfold (M) cells: important immunosurveillance posts in the intestinal epithelium
- (2013) N A Mabbott et al. Mucosal Immunology
- Transepithelial Transport of Fc-Targeted Nanoparticles by the Neonatal Fc Receptor for Oral Delivery
- (2013) E. M. Pridgen et al. Science Translational Medicine
- Redefining the gut as the motor of critical illness
- (2013) Rohit Mittal et al. TRENDS IN MOLECULAR MEDICINE
- TNF-α-induced intestinal epithelial cell shedding: implications for intestinal barrier function
- (2012) Alastair J.M. Watson et al. Annals of the New York Academy of Sciences
- Glucocorticoid receptor dimerization induces MKP1 to protect against TNF-induced inflammation
- (2012) Sofie Vandevyver et al. JOURNAL OF CLINICAL INVESTIGATION
- Crossing the barrier: Targeting epithelial receptors for enhanced oral vaccine delivery
- (2012) Bert Devriendt et al. JOURNAL OF CONTROLLED RELEASE
- Targeting the Hemoglobin Scavenger receptor CD163 in Macrophages Highly Increases the Anti-inflammatory Potency of Dexamethasone
- (2012) Jonas H Graversen et al. MOLECULAR THERAPY
- Goblet cells deliver luminal antigen to CD103+ dendritic cells in the small intestine
- (2012) Jeremiah R. McDole et al. NATURE
- Host–microbe interactions have shaped the genetic architecture of inflammatory bowel disease
- (2012) Luke Jostins et al. NATURE
- Gut-origin sepsis: Evolution of a concept
- (2012) Edwin A. Deitch SURGEON-JOURNAL OF THE ROYAL COLLEGES OF SURGEONS OF EDINBURGH AND IRELAND
- Tumor necrosis factor receptor 1-dependent depletion of mucus in immature small intestine: a potential role in neonatal necrotizing enterocolitis
- (2011) Steven J. McElroy et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- Intestinal mucosal adherence and translocation of commensal bacteria at the early onset of type 2 diabetes: molecular mechanisms and probiotic treatment
- (2011) Jacques Amar et al. EMBO Molecular Medicine
- RIP Kinase-Dependent Necrosis Drives Lethal Systemic Inflammatory Response Syndrome
- (2011) Linde Duprez et al. IMMUNITY
- Tumor Necrosis Factor Inhibits Glucocorticoid Receptor Function in Mice
- (2011) Tom Van Bogaert et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Regulation of the polymeric immunoglobulin receptor and IgA transport: new advances in environmental factors that stimulate pIgR expression and its role in mucosal immunity
- (2011) F-E Johansen et al. Mucosal Immunology
- Commensal microbiota and myelin autoantigen cooperate to trigger autoimmune demyelination
- (2011) Kerstin Berer et al. NATURE
- Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47
- (2011) Carl A Anderson et al. NATURE GENETICS
- Paneth cells, antimicrobial peptides and maintenance of intestinal homeostasis
- (2011) Charles L. Bevins et al. NATURE REVIEWS MICROBIOLOGY
- Epidermal Growth Factor Improves SurvivaL and Prevents Intestinal Injury in a Murine Model of Pseudomonas aeruginosa Pneumonia
- (2011) Jessica A. Dominguez et al. SHOCK
- Pattern Recognition Receptors and Inflammation
- (2010) Osamu Takeuchi et al. CELL
- Can We Protect the Gut in Critical Illness? The Role of Growth Factors and Other Novel Approaches
- (2010) Jessica A. Dominguez et al. CRITICAL CARE CLINICS
- Gut-Residing Segmented Filamentous Bacteria Drive Autoimmune Arthritis via T Helper 17 Cells
- (2010) Hsin-Jung Wu et al. IMMUNITY
- Enterocyte-specific A20 deficiency sensitizes to tumor necrosis factor–induced toxicity and experimental colitis
- (2010) Lars Vereecke et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci
- (2010) Andre Franke et al. NATURE GENETICS
- Stratification is the key: Inflammatory biomarkers accurately direct immunomodulatory therapy in experimental sepsis*
- (2009) Marcin F. Osuchowski et al. CRITICAL CARE MEDICINE
- Corticosteroids in the Treatment of Severe Sepsis and Septic Shock in Adults
- (2009) Djillali Annane et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Type I interferon drives tumor necrosis factor–induced lethal shock
- (2009) Liesbeth Huys et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Glucocorticoid resistance in inflammatory diseases
- (2009) Peter J Barnes et al. LANCET
- Enhancing versus Suppressive Effects of Stress on Immune Function: Implications for Immunoprotection and Immunopathology
- (2009) Firdaus S. Dhabhar NEUROIMMUNOMODULATION
- Innate immunity and intestinal microbiota in the development of Type 1 diabetes
- (2008) Li Wen et al. NATURE
- MESENTERIC LYMPH DUCT LIGATION IMPROVES SURVIVAL IN A LETHAL SHOCK MODEL
- (2008) Chirag D. Badami et al. SHOCK
Become a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get StartedAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started