Safe TNF-based antitumor therapy following p55TNFR reduction in intestinal epithelium

Microbial Translocation Across the GI Tract

(2012) Jason M. Brenchley et al.   Annual Review of Immunology

RIP Kinase-Dependent Necrosis Drives Lethal Systemic Inflammatory Response Syndrome

(2011) Linde Duprez et al.   IMMUNITY

Constitutive intestinal NF-κB does not trigger destructive inflammation unless accompanied by MAPK activation

(2011) Monica Guma et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Intestinal epithelial cells as producers but not targets of chronic TNF suffice to cause murine Crohn-like pathology

(2011) M. Roulis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Enterocyte-specific A20 deficiency sensitizes to tumor necrosis factor–induced toxicity and experimental colitis

(2010) Lars Vereecke et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Reactive oxygen species and small-conductance calcium-dependent potassium channels are key mediators of inflammation-induced hypotension and shock

(2010) Anje Cauwels et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Type I interferon drives tumor necrosis factor–induced lethal shock

(2009) Liesbeth Huys et al.   JOURNAL OF EXPERIMENTAL MEDICINE

TNF: a moonlighting protein at the interface between cancer and infection

(2008) Harald Hundsberger   Frontiers in Bioscience-Landmark

IL-17 produced by Paneth cells drives TNF-induced shock

(2008) Nozomi Takahashi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Mesenchymal cell targeting by TNF as a common pathogenic principle in chronic inflammatory joint and intestinal diseases

(2008) Maria Armaka et al.   JOURNAL OF EXPERIMENTAL MEDICINE