标题
Interaction of LRRK2 with kinase and GTPase signaling cascades
作者
关键词
-
出版物
Frontiers in Molecular Neuroscience
Volume 7, Issue -, Pages -
出版商
Frontiers Media SA
发表日期
2014-07-09
DOI
10.3389/fnmol.2014.00064
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Ribosomal Protein s15 Phosphorylation Mediates LRRK2 Neurodegeneration in Parkinson’s Disease
- (2014) Ian Martin et al. CELL
- A Parkinson's disease gene regulatory network identifies the signaling protein RGS2 as a modulator of LRRK2 activity and neuronal toxicity
- (2014) Julien Dusonchet et al. HUMAN MOLECULAR GENETICS
- Mutant LRRK2 Toxicity in Neurons Depends on LRRK2 Levels and Synuclein But Not Kinase Activity or Inclusion Bodies
- (2014) G. Skibinski et al. JOURNAL OF NEUROSCIENCE
- LRRK2 regulates synaptogenesis and dopamine receptor activation through modulation of PKA activity
- (2014) Loukia Parisiadou et al. NATURE NEUROSCIENCE
- Unbiased screen for interactors of leucine-rich repeat kinase 2 supports a common pathway for sporadic and familial Parkinson disease
- (2014) A. Beilina et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- LRRK2 phosphorylates novel tau epitopes and promotes tauopathy
- (2013) Rachel M. Bailey et al. ACTA NEUROPATHOLOGICA
- LRRK2 guides the actin cytoskeleton at growth cones together with ARHGEF7 and Tropomyosin 4
- (2013) Karina Häbig et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- A Direct Interaction between Leucine-rich Repeat Kinase 2 and Specific β-Tubulin Isoforms Regulates Tubulin Acetylation
- (2013) Bernard M. H. Law et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Leucine-rich repeat kinase 2 functionally interacts with microtubules and kinase-dependently modulates cell migration
- (2013) Mareike Caesar et al. NEUROBIOLOGY OF DISEASE
- Parkinson-related LRRK2 mutation R1441C/G/H impairs PKA phosphorylation of LRRK2 and disrupts its interaction with 14-3-3
- (2013) K. Muda et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Redox Proteomics Analyses of the Influence of Co-Expression of Wild-Type or Mutated LRRK2 and Tau on C. elegans Protein Expression and Oxidative Modification: Relevance to Parkinson Disease
- (2012) Fabio Di Domenico et al. ANTIOXIDANTS & REDOX SIGNALING
- MAP kinase signalling cascades and transcriptional regulation
- (2012) Shen-Hsi Yang et al. GENE
- Identification of novel ATP13A2 interactors and their role in α-synuclein misfolding and toxicity
- (2012) Marija Usenovic et al. HUMAN MOLECULAR GENETICS
- Quantifying Interactions of β-Synuclein and γ-Synuclein with Model Membranes
- (2012) Vanessa C. Ducas et al. JOURNAL OF MOLECULAR BIOLOGY
- ArfGAP1 Is a GTPase Activating Protein for LRRK2: Reciprocal Regulation of ArfGAP1 by LRRK2
- (2012) Y. Xiong et al. JOURNAL OF NEUROSCIENCE
- LRRK2 Controls an EndoA Phosphorylation Cycle in Synaptic Endocytosis
- (2012) Samer Matta et al. NEURON
- The IkappaB Kinase Family Phosphorylates the Parkinson’s Disease Kinase LRRK2 at Ser935 and Ser910 during Toll-Like Receptor Signaling
- (2012) Nicolas Dzamko et al. PLoS One
- GTPase Activity and Neuronal Toxicity of Parkinson's Disease–Associated LRRK2 Is Regulated by ArfGAP1
- (2012) Klodjan Stafa et al. PLoS Genetics
- Gaucher Disease Glucocerebrosidase and α-Synuclein Form a Bidirectional Pathogenic Loop in Synucleinopathies
- (2011) Joseph R. Mazzulli et al. CELL
- Cyclin-G-associated kinase modifies -synuclein expression levels and toxicity in Parkinson's disease: results from the GenePD Study
- (2011) A. Dumitriu et al. HUMAN MOLECULAR GENETICS
- Rac1 Protein Rescues Neurite Retraction Caused by G2019S Leucine-rich Repeat Kinase 2 (LRRK2)
- (2011) Diane Chan et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Milestones in PD genetics
- (2011) Thomas Gasser et al. MOVEMENT DISORDERS
- The kinase LRRK2 is a regulator of the transcription factor NFAT that modulates the severity of inflammatory bowel disease
- (2011) Zhihua Liu et al. NATURE IMMUNOLOGY
- Regulation of Physiologic Actions of LRRK2: Focus on Autophagy
- (2011) Andrew Ferree et al. Neurodegenerative Diseases
- Dysregulated LRRK2 Signaling in Response to Endoplasmic Reticulum Stress Leads to Dopaminergic Neuron Degeneration in C. elegans
- (2011) Yiyuan Yuan et al. PLoS One
- LRRK2 signaling pathways: the key to unlocking neurodegeneration?
- (2011) Daniel C. Berwick et al. TRENDS IN CELL BIOLOGY
- Inhibition of LRRK2 kinase activity leads to dephosphorylation of Ser910/Ser935, disruption of 14-3-3 binding and altered cytoplasmic localization
- (2010) Nicolas Dzamko et al. BIOCHEMICAL JOURNAL
- 14-3-3 binding to LRRK2 is disrupted by multiple Parkinson's disease-associated mutations and regulates cytoplasmic localization
- (2010) R. Jeremy Nichols et al. BIOCHEMICAL JOURNAL
- Leucine-rich repeat kinase 2 induces α-synuclein expression via the extracellular signal-regulated kinase pathway
- (2010) Iria Carballo-Carbajal et al. CELLULAR SIGNALLING
- Membrane Curvature Induction and Tubulation Are Common Features of Synucleins and Apolipoproteins
- (2010) Jobin Varkey et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- MKK6 binds and regulates expression of Parkinson’s disease-related protein LRRK2
- (2010) Cindy H. Hsu et al. JOURNAL OF NEUROCHEMISTRY
- Pathogenic LRRK2 negatively regulates microRNA-mediated translational repression
- (2010) Stephan Gehrke et al. NATURE
- The role of leucine-rich repeat kinase 2 (LRRK2) in Parkinson's disease
- (2010) Mark R. Cookson NATURE REVIEWS NEUROSCIENCE
- LRRK2-mediated neurodegeneration and dysfunction of dopaminergic neurons in a Caenorhabditis elegans model of Parkinson's disease
- (2010) Chen Yao et al. NEUROBIOLOGY OF DISEASE
- Current status and future directions of gene expression profiling in Parkinson's disease
- (2010) James G. Greene NEUROBIOLOGY OF DISEASE
- LRRK2 and the Stress Response: Interaction with MKKs and JNK-Interacting Proteins
- (2010) C.H. Hsu et al. Neurodegenerative Diseases
- Genetic Animal Models of Parkinson's Disease
- (2010) Ted M. Dawson et al. NEURON
- The Parkinson's Disease Associated LRRK2 Exhibits Weaker In Vitro Phosphorylation of 4E-BP Compared to Autophosphorylation
- (2010) Azad Kumar et al. PLoS One
- Loss of leucine-rich repeat kinase 2 causes impairment of protein degradation pathways, accumulation of -synuclein, and apoptotic cell death in aged mice
- (2010) Y. Tong et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- PINK1 Is Selectively Stabilized on Impaired Mitochondria to Activate Parkin
- (2010) Derek P. Narendra et al. PLOS BIOLOGY
- Leucine-Rich Repeat Kinase 2 Mutations and Parkinson's Disease: Three Questions
- (2009) Elisa Greggio et al. ASN Neuro
- Mutations in the LRRK2 Roc-COR tandem domain link Parkinson's disease to Wnt signalling pathways
- (2009) Rosa M. Sancho et al. HUMAN MOLECULAR GENETICS
- Leucine-rich repeat kinase 2 interacts with Parkin, DJ-1 and PINK-1 in a Drosophila melanogaster model of Parkinson's disease
- (2009) K. Venderova et al. HUMAN MOLECULAR GENETICS
- LRRK2 regulates autophagic activity and localizes to specific membrane microdomains in a novel human genomic reporter cellular model
- (2009) Javier Alegre-Abarrategui et al. HUMAN MOLECULAR GENETICS
- Caenorhabditits elegansLRK-1 and PINK-1 Act Antagonistically in Stress Response and Neurite Outgrowth
- (2009) Julia Sämann et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Curvature Dynamics of α-Synuclein Familial Parkinson Disease Mutants
- (2009) Jason D. Perlmutter et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The Parkinson disease-associated protein kinase LRRK2 exhibits MAPKKK activity and phosphorylates MKK3/6 and MKK4/7,in vitro
- (2009) Christian Johannes Gloeckner et al. JOURNAL OF NEUROCHEMISTRY
- Phosphorylation of Ezrin/Radixin/Moesin Proteins by LRRK2 Promotes the Rearrangement of Actin Cytoskeleton in Neuronal Morphogenesis
- (2009) L. Parisiadou et al. JOURNAL OF NEUROSCIENCE
- The Parkinson Disease Protein Leucine-Rich Repeat Kinase 2 Transduces Death Signals via Fas-Associated Protein with Death Domain and Caspase-8 in a Cellular Model of Neurodegeneration
- (2009) C. C.-Y. Ho et al. JOURNAL OF NEUROSCIENCE
- LRRK2 Modulates Vulnerability to Mitochondrial Dysfunction in Caenorhabditis elegans
- (2009) S. Saha et al. JOURNAL OF NEUROSCIENCE
- Parkinson's disease
- (2009) Andrew J Lees et al. LANCET
- CHIP regulates leucine-rich repeat kinase-2 ubiquitination, degradation, and toxicity
- (2009) Han Seok Ko et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Phosphorylation of 4E-BP by LRRK2 affects the maintenance of dopaminergic neurons in Drosophila
- (2008) Yuzuru Imai et al. EMBO JOURNAL
- LRRK2 regulates synaptic vesicle endocytosis
- (2008) Narae Shin et al. EXPERIMENTAL CELL RESEARCH
- Emerging pathways in genetic Parkinson’s disease: tangles, Lewy bodies and LRRK2
- (2008) Michael J. Devine et al. FEBS Journal
- Genomewide association study for susceptibility genes contributing to familial Parkinson disease
- (2008) Nathan Pankratz et al. HUMAN GENETICS
- Ancient Origin of the Parkinson Disease Gene LRRK2
- (2008) Ignacio Marín JOURNAL OF MOLECULAR EVOLUTION
- Role of autophagy in G2019S-LRRK2-associated neurite shortening in differentiated SH-SY5Y cells
- (2008) Edward D. Plowey et al. JOURNAL OF NEUROCHEMISTRY
- Phenotype, genotype, and worldwide genetic penetrance of LRRK2-associated Parkinson's disease: a case-control study
- (2008) Daniel G Healy et al. LANCET NEUROLOGY
- Dispensable role of Drosophila ortholog of LRRK2 kinase activity in survival of dopaminergic neurons
- (2008) Danling Wang et al. Molecular Neurodegeneration
- Wild-type LRRK2 but not its mutant attenuates stress-induced cell death via ERK pathway
- (2008) Anthony K.F. Liou et al. NEUROBIOLOGY OF DISEASE
- A Drosophila model for LRRK2-linked parkinsonism
- (2008) Z. Liu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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