A Direct Interaction between Leucine-rich Repeat Kinase 2 and Specific β-Tubulin Isoforms Regulates Tubulin Acetylation
出版年份 2013 全文链接
标题
A Direct Interaction between Leucine-rich Repeat Kinase 2 and Specific β-Tubulin Isoforms Regulates Tubulin Acetylation
作者
关键词
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出版物
JOURNAL OF BIOLOGICAL CHEMISTRY
Volume 289, Issue 2, Pages 895-908
出版商
American Society for Biochemistry & Molecular Biology (ASBMB)
发表日期
2013-11-26
DOI
10.1074/jbc.m113.507913
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization
- (2013) Shireen A. Sarraf et al. NATURE
- Whispering dysphonia (DYT4 dystonia) is caused by a mutation in theTUBB4gene
- (2012) Katja Lohmann et al. ANNALS OF NEUROLOGY
- Mutations in the autoregulatory domain of β-tubulin 4a cause hereditary dystonia
- (2012) Joshua Hersheson et al. ANNALS OF NEUROLOGY
- The importance of Wnt signalling for neurodegeneration in Parkinson's disease
- (2012) Daniel C. Berwick et al. BIOCHEMICAL SOCIETY TRANSACTIONS
- Posttranslational Acetylation of α-Tubulin Constrains Protofilament Number in Native Microtubules
- (2012) Juan G. Cueva et al. CURRENT BIOLOGY
- LRRK2 functions as a Wnt signaling scaffold, bridging cytosolic proteins and membrane-localized LRP6
- (2012) Daniel C. Berwick et al. HUMAN MOLECULAR GENETICS
- Proteomic Analyses Reveal Divergent Ubiquitylation Site Patterns in Murine Tissues
- (2012) Sebastian A. Wagner et al. MOLECULAR & CELLULAR PROTEOMICS
- LRRK2 Phosphorylates Tubulin-Associated Tau but Not the Free Molecule: LRRK2-Mediated Regulation of the Tau-Tubulin Association and Neurite Outgrowth
- (2012) Fumitaka Kawakami et al. PLoS One
- Biochemical Characterization of Highly Purified Leucine-Rich Repeat Kinases 1 and 2 Demonstrates Formation of Homodimers
- (2012) Laura Civiero et al. PLoS One
- Ser1292 Autophosphorylation Is an Indicator of LRRK2 Kinase Activity and Contributes to the Cellular Effects of PD Mutations
- (2012) Z. Sheng et al. Science Translational Medicine
- LRRK2 Parkinson disease mutations enhance its microtubule association
- (2011) Lauren R. Kett et al. HUMAN MOLECULAR GENETICS
- Characterization of a selective inhibitor of the Parkinson's disease kinase LRRK2
- (2011) Xianming Deng et al. Nature Chemical Biology
- LRRK2 signaling pathways: the key to unlocking neurodegeneration?
- (2011) Daniel C. Berwick et al. TRENDS IN CELL BIOLOGY
- Genome-Wide Association Study Confirms SNPs inSNCAand theMAPTRegion as Common Risk Factors for Parkinson Disease
- (2010) Todd L. Edwards et al. ANNALS OF HUMAN GENETICS
- Inhibition of LRRK2 kinase activity leads to dephosphorylation of Ser910/Ser935, disruption of 14-3-3 binding and altered cytoplasmic localization
- (2010) Nicolas Dzamko et al. BIOCHEMICAL JOURNAL
- 14-3-3 binding to LRRK2 is disrupted by multiple Parkinson's disease-associated mutations and regulates cytoplasmic localization
- (2010) R. Jeremy Nichols et al. BIOCHEMICAL JOURNAL
- Human TUBB3 Mutations Perturb Microtubule Dynamics, Kinesin Interactions, and Axon Guidance
- (2010) Max A. Tischfield et al. CELL
- Mutations in the neuronal β-tubulin subunit TUBB3 result in malformation of cortical development and neuronal migration defects
- (2010) Karine Poirier et al. HUMAN MOLECULAR GENETICS
- TUBA1A mutations cause wide spectrum lissencephaly (smooth brain) and suggest that multiple neuronal migration pathways converge on alpha tubulins
- (2010) Ravinesh A. Kumar et al. HUMAN MOLECULAR GENETICS
- MKK6 binds and regulates expression of Parkinson’s disease-related protein LRRK2
- (2010) Cindy H. Hsu et al. JOURNAL OF NEUROCHEMISTRY
- Insight into the mode of action of the LRRK2 Y1699C pathogenic mutant
- (2010) Veronique Daniëls et al. JOURNAL OF NEUROCHEMISTRY
- LRRK2 G2019S Mutation Induces Dendrite Degeneration through Mislocalization and Phosphorylation of Tau by Recruiting Autoactivated GSK3
- (2010) C.-H. Lin et al. JOURNAL OF NEUROSCIENCE
- Phosphopeptide Analysis Reveals Two Discrete Clusters of Phosphorylation in the N-Terminus and the Roc Domain of the Parkinson-Disease Associated Protein Kinase LRRK2
- (2010) Christian Johannes Gloeckner et al. JOURNAL OF PROTEOME RESEARCH
- MEC-17 is an α-tubulin acetyltransferase
- (2010) Jyothi S. Akella et al. NATURE
- Impaired dopaminergic neurotransmission and microtubule-associated protein tau alterations in human LRRK2 transgenic mice
- (2010) H.L. Melrose et al. NEUROBIOLOGY OF DISEASE
- LRRK2 and the Stress Response: Interaction with MKKs and JNK-Interacting Proteins
- (2010) C.H. Hsu et al. Neurodegenerative Diseases
- The major -tubulin K40 acetyltransferase TAT1 promotes rapid ciliogenesis and efficient mechanosensation
- (2010) T. Shida et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- GTPase Activity Plays a Key Role in the Pathobiology of LRRK2
- (2010) Yulan Xiong et al. PLoS Genetics
- Leucine-Rich Repeat Kinase 2 Mutations and Parkinson's Disease: Three Questions
- (2009) Elisa Greggio et al. ASN Neuro
- The Parkinson’s disease kinase LRRK2 autophosphorylates its GTPase domain at multiple sites
- (2009) Elisa Greggio et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Identification of the Autophosphorylation Sites of LRRK2
- (2009) Shogo Kamikawaji et al. BIOCHEMISTRY
- LRRK2 in Parkinson’s disease: genetic and clinical studies from patients
- (2009) Udhaya Kumari et al. FEBS Journal
- Highly Efficient Multicistronic Lentiviral Vectors with Peptide 2A Sequences
- (2009) Abdelilah Ibrahimi et al. HUMAN GENE THERAPY
- Mutations in the LRRK2 Roc-COR tandem domain link Parkinson's disease to Wnt signalling pathways
- (2009) Rosa M. Sancho et al. HUMAN MOLECULAR GENETICS
- Leucine-rich repeat kinase 2 phosphorylates brain tubulin-beta isoforms and modulates microtubule stability - a point of convergence in Parkinsonian neurodegeneration?
- (2009) Frank Gillardon JOURNAL OF NEUROCHEMISTRY
- The Parkinson disease-associated protein kinase LRRK2 exhibits MAPKKK activity and phosphorylates MKK3/6 and MKK4/7,in vitro
- (2009) Christian Johannes Gloeckner et al. JOURNAL OF NEUROCHEMISTRY
- Phosphorylation of Ezrin/Radixin/Moesin Proteins by LRRK2 Promotes the Rearrangement of Actin Cytoskeleton in Neuronal Morphogenesis
- (2009) L. Parisiadou et al. JOURNAL OF NEUROSCIENCE
- The Parkinson Disease Protein Leucine-Rich Repeat Kinase 2 Transduces Death Signals via Fas-Associated Protein with Death Domain and Caspase-8 in a Cellular Model of Neurodegeneration
- (2009) C. C.-Y. Ho et al. JOURNAL OF NEUROSCIENCE
- Mutations in the β-tubulin gene TUBB2B result in asymmetrical polymicrogyria
- (2009) Xavier Hubert Jaglin et al. NATURE GENETICS
- Genome-wide association study reveals genetic risk underlying Parkinson's disease
- (2009) Javier Simón-Sánchez et al. NATURE GENETICS
- Mutant LRRK2 R1441G BAC transgenic mice recapitulate cardinal features of Parkinson's disease
- (2009) Yanping Li et al. NATURE NEUROSCIENCE
- Interaction of elongation factor 1-alpha with leucine-rich repeat kinase 2 impairs kinase activity and microtubule bundling in vitro
- (2009) F. Gillardon NEUROSCIENCE
- R1441C mutation in LRRK2 impairs dopaminergic neurotransmission in mice
- (2009) Y. Tong et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Axonal transport and the delivery of pre-synaptic components
- (2008) Ann YN Goldstein et al. CURRENT OPINION IN NEUROBIOLOGY
- Role of autophagy in G2019S-LRRK2-associated neurite shortening in differentiated SH-SY5Y cells
- (2008) Edward D. Plowey et al. JOURNAL OF NEUROCHEMISTRY
- The Roc domain of leucine-rich repeat kinase 2 is sufficient for interaction with microtubules
- (2008) Payal N. Gandhi et al. JOURNAL OF NEUROSCIENCE RESEARCH
- Phenotype, genotype, and worldwide genetic penetrance of LRRK2-associated Parkinson's disease: a case-control study
- (2008) Daniel G Healy et al. LANCET NEUROLOGY
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