Lower Affinity T Cells are Critical Components and Active Participants of the Immune Response
出版年份 2015 全文链接
标题
Lower Affinity T Cells are Critical Components and Active Participants of the Immune Response
作者
关键词
-
出版物
Frontiers in Immunology
Volume 6, Issue -, Pages -
出版商
Frontiers Media SA
发表日期
2015-09-10
DOI
10.3389/fimmu.2015.00468
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- T Cell Receptor Cross-Reactivity between Similar Foreign and Self Peptides Influences Naive Cell Population Size and Autoimmunity
- (2015) Ryan W. Nelson et al. IMMUNITY
- Clonal Deletion Prunes but Does Not Eliminate Self-Specific αβ CD8+ T Lymphocytes
- (2015) Wong Yu et al. IMMUNITY
- Force-dependent transition in the T-cell receptor β-subunit allosterically regulates peptide discrimination and pMHC bond lifetime
- (2015) Dibyendu Kumar Das et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Deconstructing the Peptide-MHC Specificity of T Cell Recognition
- (2014) Michael E. Birnbaum et al. CELL
- Coreceptor Scanning by the T Cell Receptor Provides a Mechanism for T Cell Tolerance
- (2014) Ondrej Stepanek et al. CELL
- Accumulation of Dynamic Catch Bonds between TCR and Agonist Peptide-MHC Triggers T Cell Signaling
- (2014) Baoyu Liu et al. CELL
- Revisiting Thymic Positive Selection and the Mature T Cell Repertoire for Antigen
- (2014) Nienke Vrisekoop et al. IMMUNITY
- T-Cell-Receptor-Dependent Signal Intensity Dominantly Controls CD4+ T Cell Polarization In Vivo
- (2014) Nicholas van Panhuys et al. IMMUNITY
- Memory CD8+ T Cells Use Cell-Intrinsic Lipolysis to Support the Metabolic Programming Necessary for Development
- (2014) David O’Sullivan et al. IMMUNITY
- Progression of Relapsing-Remitting Demyelinating Disease Does Not Require Increased TCR Affinity or Epitope Spread
- (2014) Anna E. Kersh et al. JOURNAL OF IMMUNOLOGY
- TCR Affinity and Tolerance Mechanisms Converge To Shape T Cell Diabetogenic Potential
- (2014) Maria Bettini et al. JOURNAL OF IMMUNOLOGY
- The self-obsession of T cells: how TCR signaling thresholds affect fate 'decisions' and effector function
- (2014) Kristin A Hogquist et al. NATURE IMMUNOLOGY
- The tyrosine phosphatase PTPN22 discriminates weak self peptides from strong agonist TCR signals
- (2014) Robert J Salmond et al. NATURE IMMUNOLOGY
- The TCR's sensitivity to self peptide–MHC dictates the ability of naive CD8+ T cells to respond to foreign antigens
- (2014) Ross B Fulton et al. NATURE IMMUNOLOGY
- Intrinsic CD4+ T cell sensitivity and response to a pathogen are set and sustained by avidity for thymic and peripheral complexes of self peptide and MHC
- (2014) Stephen P Persaud et al. NATURE IMMUNOLOGY
- Antigen affinity and antigen dose exert distinct influences on CD4 T-cell differentiation
- (2014) S. Keck et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Single Naive CD4+ T Cells from a Diverse Repertoire Produce Different Effector Cell Types during Infection
- (2013) Noah J. Tubo et al. CELL
- 2D TCR-pMHC-CD8 kinetics determines T-cell responses in a self-antigen-specific TCR system
- (2013) Baoyu Liu et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Sustained Interactions between T Cell Receptors and Antigens Promote the Differentiation of CD4+ Memory T Cells
- (2013) Chulwoo Kim et al. IMMUNITY
- T Cell-Positive Selection Uses Self-Ligand Binding Strength to Optimize Repertoire Recognition of Foreign Antigens
- (2013) Judith N. Mandl et al. IMMUNITY
- SHP-1 phosphatase activity counteracts increased T cell receptor affinity
- (2013) Michael Hebeisen et al. JOURNAL OF CLINICAL INVESTIGATION
- Themis sets the signal threshold for positive and negative selection in T-cell development
- (2013) Guo Fu et al. NATURE
- The transcription factor IRF4 is essential for TCR affinity–mediated metabolic programming and clonal expansion of T cells
- (2013) Kevin Man et al. NATURE IMMUNOLOGY
- T-cell receptor affinity and avidity defines antitumor response and autoimmunity in T-cell immunotherapy
- (2013) S. Zhong et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Thymoproteasome subunit- 5T generates peptide-MHC complexes specialized for positive selection
- (2013) Y. Xing et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Murine thymic selection quantified using a unique method to capture deleted T cells
- (2013) G. L. Stritesky et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- CD8 memory T cells have a bioenergetic advantage that underlies their rapid recall ability
- (2013) G. J. W. van der Windt et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Low-Affinity T Cells Are Programmed to Maintain Normal Primary Responses but Are Impaired in Their Recall to Low-Affinity Ligands
- (2013) Karin M. Knudson et al. Cell Reports
- Transnuclear TRP1-Specific CD8 T Cells with High or Low Affinity TCRs Show Equivalent Antitumor Activity
- (2013) S. K. Dougan et al. Cancer Immunology Research
- Role of T Cell Receptor Affinity in the Efficacy and Specificity of Adoptive T Cell Therapies
- (2013) Jennifer D. Stone et al. Frontiers in Immunology
- Estimating the Diversity, Completeness, and Cross-Reactivity of the T Cell Repertoire
- (2013) Veronika I. Zarnitsyna et al. Frontiers in Immunology
- Monitoring the Dynamics of T Cell Clonal Diversity Using Recombinant Peptide:MHC Technology
- (2013) J. Lori Blanchfield et al. Frontiers in Immunology
- Selection of Self-Reactive T Cells in the Thymus
- (2012) Gretta L. Stritesky et al. Annual Review of Immunology
- A Broad Range of Self-Reactivity Drives Thymic Regulatory T Cell Selection to Limit Responses to Self
- (2012) Hyang-Mi Lee et al. IMMUNITY
- T Cell Affinity Regulates Asymmetric Division, Effector Cell Differentiation, and Tissue Pathology
- (2012) Carolyn G. King et al. IMMUNITY
- Insights fromin situanalysis of TCR-pMHC recognition: response of an interaction network
- (2012) Cheng Zhu et al. IMMUNOLOGICAL REVIEWS
- Thymic negative selection is functional in NOD mice
- (2012) Michael Mingueneau et al. JOURNAL OF EXPERIMENTAL MEDICINE
- A TCR Affinity Threshold Regulates Memory CD4 T Cell Differentiation following Vaccination
- (2012) C. K. Baumgartner et al. JOURNAL OF IMMUNOLOGY
- The Role of Naive T Cell Precursor Frequency and Recruitment in Dictating Immune Response Magnitude
- (2012) M. K. Jenkins et al. JOURNAL OF IMMUNOLOGY
- Low 2-Dimensional CD4 T Cell Receptor Affinity for Myelin Sets in Motion Delayed Response Kinetics
- (2012) Kristen M. Rosenthal et al. PLoS One
- Detection of an autoreactive T-cell population within the polyclonal repertoire that undergoes distinct autoimmune regulator (Aire)-mediated selection
- (2012) R. T. Taniguchi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- CD4 and CD8 T cells require different membrane gangliosides for activation
- (2012) M. Nagafuku et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- T-Cell Tolerance: Central and Peripheral
- (2012) Y. Xing et al. Cold Spring Harbor Perspectives in Biology
- Priming with very low-affinity peptide ligands gives rise to CD8+ T-cell effectors with enhanced function but with greater susceptibility to transforming growth factor (TGF)β-mediated suppression
- (2011) Jeremy A. O’Sullivan et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- T Cell Receptor Signaling Is Limited by Docking Geometry to Peptide-Major Histocompatibility Complex
- (2011) Jarrett J. Adams et al. IMMUNITY
- The Transcription Factor Myc Controls Metabolic Reprogramming upon T Lymphocyte Activation
- (2011) Ruoning Wang et al. IMMUNITY
- Two-Stage Cooperative T Cell Receptor-Peptide Major Histocompatibility Complex-CD8 Trimolecular Interactions Amplify Antigen Discrimination
- (2011) Ning Jiang et al. IMMUNITY
- A Single Autoimmune T Cell Receptor Recognizes More Than a Million Different Peptides
- (2011) Linda Wooldridge et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- High prevalence of low affinity peptide–MHC II tetramer–negative effectors during polyclonal CD4+T cell responses
- (2011) Joseph J. Sabatino et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Arthritogenic Self-Reactive CD4+ T Cells Acquire an FR4hiCD73hi Anergic State in the Presence of Foxp3+ Regulatory T Cells
- (2011) R. J. Martinez et al. JOURNAL OF IMMUNOLOGY
- Primary Human CD4+ T Cells Have Diverse Levels of Membrane Lipid Order That Correlate with Their Function
- (2011) L. Miguel et al. JOURNAL OF IMMUNOLOGY
- Quantifying Antigen-Specific CD4 T Cells during a Viral Infection: CD4 T Cell Responses Are Larger Than We Think
- (2011) D. S. McDermott et al. JOURNAL OF IMMUNOLOGY
- Interaction of Streptavidin-Based Peptide-MHC Oligomers (Tetramers) with Cell-Surface TCRs
- (2011) J. D. Stone et al. JOURNAL OF IMMUNOLOGY
- Force Generation upon T Cell Receptor Engagement
- (2011) Julien Husson et al. PLoS One
- Force Measurements of TCR/pMHC Recognition at T Cell Surface
- (2011) Pierre-Henri Puech et al. PLoS One
- Antigen-stimulated CD4 T-cell expansion is inversely and log-linearly related to precursor number
- (2011) J. Quiel et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- On the Composition of the Preimmune Repertoire of T Cells Specific for Peptide–Major Histocompatibility Complex Ligands
- (2010) Marc K. Jenkins et al. Annual Review of Immunology
- Persistent viral infection in humans can drive high frequency low-affinity T-cell expansions
- (2010) Naeem Khan et al. IMMUNOLOGY
- Reduced Functional Avidity Promotes Central and Effector Memory CD4 T Cell Responses to Tumor-Associated Antigens
- (2010) S. Caserta et al. JOURNAL OF IMMUNOLOGY
- The kinetics of two-dimensional TCR and pMHC interactions determine T-cell responsiveness
- (2010) Jun Huang et al. NATURE
- TCR–peptide–MHC interactions in situ show accelerated kinetics and increased affinity
- (2010) Johannes B. Huppa et al. NATURE
- CD4 and CD8 binding to MHC molecules primarily acts to enhance Lck delivery
- (2010) M. N. Artyomov et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Impact of TCR-Binding Properties and Antigen Presentation Format on T Cell Responsiveness
- (2009) A. S. Chervin et al. JOURNAL OF IMMUNOLOGY
- Complete but curtailed T-cell response to very low-affinity antigen
- (2009) Dietmar Zehn et al. NATURE
- The function of follicular helper T cells is regulated by the strength of T cell antigen receptor binding
- (2009) Nicolas Fazilleau et al. NATURE IMMUNOLOGY
- Tracking epitope-specific T cells
- (2009) James J Moon et al. Nature Protocols
- Positive selection optimizes the number and function of MHCII-restricted CD4+ T cell clones in the naive polyclonal repertoire
- (2009) H. H. Chu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Rapid Culling of the CD4+ T Cell Repertoire in the Transition from Effector to Memory
- (2008) Matthew A. Williams et al. IMMUNITY
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started