The transcription factor IRF4 is essential for TCR affinity–mediated metabolic programming and clonal expansion of T cells

Metabolic Regulation of T Lymphocytes

(2013) Nancie J. MacIver et al.   Annual Review of Immunology

Posttranscriptional Control of T Cell Effector Function by Aerobic Glycolysis

(2013) Chih-Hao Chang et al.   CELL

The Subread aligner: fast, accurate and scalable read mapping by seed-and-vote

(2013) Yang Liao et al.   NUCLEIC ACIDS RESEARCH

A Validated Regulatory Network for Th17 Cell Specification

(2012) Maria Ciofani et al.   CELL

Enhanced phosphoinositide 3-kinase(p110α) activity prevents diabetes-induced cardiomyopathy and superoxide generation in a mouse model of diabetes

(2012) R. H. Ritchie et al.   DIABETOLOGIA

Unlike CD4+ T-cell help, CD28 costimulation is necessary for effective primary CD8+ T-cell influenza-specific immunity

(2012) Shirley G.K. Seah et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

T Cell Affinity Regulates Asymmetric Division, Effector Cell Differentiation, and Tissue Pathology

(2012) Carolyn G. King et al.   IMMUNITY

Transcription Factor Foxo1 Represses T-bet-Mediated Effector Functions and Promotes Memory CD8+ T Cell Differentiation

(2012) Rajesh R. Rao et al.   IMMUNITY

Metabolic switching and fuel choice during T-cell differentiation and memory development

(2012) Gerritje J. W. Windt et al.   IMMUNOLOGICAL REVIEWS

PDK1 regulation of mTOR and hypoxia-inducible factor 1 integrate metabolism and migration of CD8+T cells

(2012) David K. Finlay et al.   JOURNAL OF EXPERIMENTAL MEDICINE

BATF–JUN is critical for IRF4-mediated transcription in T cells

(2012) Peng Li et al.   NATURE

Metabolic checkpoints in activated T cells

(2012) Ruoning Wang et al.   NATURE IMMUNOLOGY

A Genomic Regulatory Element That Directs Assembly and Function of Immune-Specific AP-1-IRF Complexes

(2012) E. Glasmacher et al.   SCIENCE

The Transcription Factor Myc Controls Metabolic Reprogramming upon T Lymphocyte Activation

(2011) Ruoning Wang et al.   IMMUNITY

The transcriptional regulators Id2 and Id3 control the formation of distinct memory CD8+ T cell subsets

(2011) Cliff Y Yang et al.   NATURE IMMUNOLOGY

The transcription factors Blimp-1 and IRF4 jointly control the differentiation and function of effector regulatory T cells

(2011) Erika Cretney et al.   NATURE IMMUNOLOGY

T-cell receptor signals direct the composition and function of the memory CD8+ T-cell pool

(2010) J. E. Smith-Garvin et al.   BLOOD

Effector and memory CD8+ T cell differentiation: toward a molecular understanding of fate determination

(2010) Gabrielle T Belz et al.   CURRENT OPINION IN IMMUNOLOGY

Interferon-Regulatory Factor 4 Is Essential for the Developmental Program of T Helper 9 Cells

(2010) Valérie Staudt et al.   IMMUNITY

Apoptosis Threshold Set by Noxa and Mcl-1 after T Cell Activation Regulates Competitive Selection of High-Affinity Clones

(2010) Felix M. Wensveen et al.   IMMUNITY

Transcriptional Repressor Blimp-1 Promotes CD8+ T Cell Terminal Differentiation and Represses the Acquisition of Central Memory T Cell Properties

(2009) Rachel L. Rutishauser et al.   IMMUNITY

Analysis of Interleukin-21-Induced Prdm1 Gene Regulation Reveals Functional Cooperation of STAT3 and IRF4 Transcription Factors

(2009) Hyokjoon Kwon et al.   IMMUNITY

Blimp-1 Transcription Factor Is Required for the Differentiation of Effector CD8+ T Cells and Memory Responses

(2009) Axel Kallies et al.   IMMUNITY

Runx3 and T-box proteins cooperate to establish the transcriptional program of effector CTLs

(2009) Fernando Cruz-Guilloty et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Complete but curtailed T-cell response to very low-affinity antigen

(2009) Dietmar Zehn et al.   NATURE

Regulatory T-cell suppressor program co-opts transcription factor IRF4 to control TH2 responses

(2009) Ye Zheng et al.   NATURE

Foxo1 links homing and survival of naive T cells by regulating L-selectin, CCR7 and interleukin 7 receptor

(2009) Yann M Kerdiles et al.   NATURE IMMUNOLOGY

Different T Cell Receptor Signals Determine CD8+ Memory Versus Effector Development

(2009) E. Teixeiro et al.   SCIENCE

Model-based Analysis of ChIP-Seq (MACS)

(2008) Yong Zhang et al.   GENOME BIOLOGY