Effects of Prolonged GRP78 Haploinsufficiency on Organ Homeostasis, Behavior, Cancer and Chemotoxic Resistance in Aged Mice
出版年份 2017 全文链接
标题
Effects of Prolonged GRP78 Haploinsufficiency on Organ Homeostasis, Behavior, Cancer and Chemotoxic Resistance in Aged Mice
作者
关键词
-
出版物
Scientific Reports
Volume 7, Issue 1, Pages -
出版商
Springer Nature
发表日期
2017-02-01
DOI
10.1038/srep40919
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Design, purification and assessment of GRP78 binding peptide-linked Subunit A of Subtilase cytotoxic for targeting cancer cells
- (2016) Lichao Zhang et al. BMC BIOTECHNOLOGY
- Compounds Triggering ER Stress Exert Anti-Melanoma Effects and Overcome BRAF Inhibitor Resistance
- (2016) Michaël Cerezo et al. CANCER CELL
- Endoplasmic Reticulum Stress Protein GRP78 Modulates Lipid Metabolism to Control Drug Sensitivity and Antitumor Immunity in Breast Cancer
- (2016) Katherine L. Cook et al. CANCER RESEARCH
- A GRP78-Directed Monoclonal Antibody Recaptures Response in Refractory Multiple Myeloma with Extramedullary Involvement
- (2016) L. Rasche et al. CLINICAL CANCER RESEARCH
- Clients and Oncogenic Roles of Molecular Chaperone gp96/grp94
- (2016) Ephraim A. Ansa-Addo et al. CURRENT TOPICS IN MEDICINAL CHEMISTRY
- Expression of GRP78, Master Regulator of the Unfolded Protein Response, Increases Chemoresistance in Pancreatic Ductal Adenocarcinoma
- (2016) J. B. Gifford et al. MOLECULAR CANCER THERAPEUTICS
- RNAi Screening of the Glucose-Regulated Chaperones in Cancer with Self-Assembled siRNA Nanostructures
- (2016) Mayurbhai R. Patel et al. NANO LETTERS
- A Periodic Diet that Mimics Fasting Promotes Multi-System Regeneration, Enhanced Cognitive Performance, and Healthspan
- (2015) Sebastian Brandhorst et al. Cell Metabolism
- GRP78/BiP/HSPA5/Dna K is a universal therapeutic target for human disease
- (2015) Laurence Booth et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Role of the unfolded protein response, GRP78 and GRP94 in organ homeostasis
- (2015) Genyuan Zhu et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Dietary compound isoliquiritigenin targets GRP78 to chemosensitize breast cancer stem cells via β-catenin/ABCG2 signaling
- (2014) Neng Wang et al. CARCINOGENESIS
- Targeting GRP78 and antiestrogen resistance in breast cancer
- (2013) Katherine L Cook et al. Future Medicinal Chemistry
- Cancer Cells Resistant to Therapy Promote Cell Surface Relocalization of GRP78 Which Complexes with PI3K and Enhances PI(3,4,5)P3 Production
- (2013) Yi Zhang et al. PLoS One
- The Molecular Chaperone GRP78/BiP in the Development of Chemoresistance: Mechanism and Possible Treatment
- (2013) Corinna Roller et al. Frontiers in Pharmacology
- The critical roles of endoplasmic reticulum chaperones and unfolded protein response in tumorigenesis and anticancer therapies
- (2012) B Luo et al. ONCOGENE
- Beyond the endoplasmic reticulum: atypical GRP78 in cell viability, signalling and therapeutic targeting
- (2011) Min Ni et al. BIOCHEMICAL JOURNAL
- Inducible knockout of GRP78/BiP in the hematopoietic system suppresses Pten-null leukemogenesis and AKT oncogenic signaling
- (2011) S. Wey et al. BLOOD
- Novel Mechanism of Anti-apoptotic Function of 78-kDa Glucose-regulated Protein (GRP78)
- (2011) Hui Zhou et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- ER stress in retinal degeneration: a target for rational therapy?
- (2011) Ana Griciuc et al. TRENDS IN MOLECULAR MEDICINE
- Grp78 Heterozygosity Regulates Chaperone Balance in Exocrine Pancreas with Differential Response to Cerulein-Induced Acute Pancreatitis
- (2010) Risheng Ye et al. AMERICAN JOURNAL OF PATHOLOGY
- The critical role of GRP78 in physiologic and pathologic stress
- (2010) Kyle T Pfaffenbach et al. CURRENT OPINION IN CELL BIOLOGY
- Overexpressing GRP78 influences Ca2+ handling and function of mitochondria in astrocytes after ischemia-like stress
- (2010) Yi-Bing Ouyang et al. MITOCHONDRION
- Restoration of visual function in P23H rhodopsin transgenic rats by gene delivery of BiP/Grp78
- (2010) M. S. Gorbatyuk et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Role of the Unfolded Protein Response Regulator GRP78/BiP in Development, Cancer, and Neurological Disorders
- (2009) Miao Wang et al. ANTIOXIDANTS & REDOX SIGNALING
- GRP78: A Multifunctional Receptor on the Cell Surface
- (2009) Mario Gonzalez–Gronow et al. ANTIOXIDANTS & REDOX SIGNALING
- Grp78 Heterozygosity Promotes Adaptive Unfolded Protein Response and Attenuates Diet-Induced Obesity and Insulin Resistance
- (2009) R. Ye et al. DIABETES
- Critical Role of the Stress Chaperone GRP78/BiP in Tumor Proliferation, Survival, and Tumor Angiogenesis in Transgene-Induced Mammary Tumor Development
- (2008) D. Dong et al. CANCER RESEARCH
- The unfolded protein response regulator GRP78/BiP is required for endoplasmic reticulum integrity and stress-induced autophagy in mammalian cells
- (2008) J Li et al. CELL DEATH AND DIFFERENTIATION
- Aging Impairs the Unfolded Protein Response to Sleep Deprivation and Leads to Proapoptotic Signaling
- (2008) N. Naidoo et al. JOURNAL OF NEUROSCIENCE
- Stress Chaperone GRP78/BiP Confers Chemoresistance to Tumor-Associated Endothelial Cells
- (2008) J. J. Virrey et al. MOLECULAR CANCER RESEARCH
- Pten null prostate tumorigenesis and AKT activation are blocked by targeted knockout of ER chaperone GRP78/BiP in prostate epithelium
- (2008) Y. Fu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Decreased enzyme activities of chaperones PDI and BiP in aged mouse livers
- (2007) Jonathan E. Nuss et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now