The critical roles of endoplasmic reticulum chaperones and unfolded protein response in tumorigenesis and anticancer therapies
出版年份 2012 全文链接
标题
The critical roles of endoplasmic reticulum chaperones and unfolded protein response in tumorigenesis and anticancer therapies
作者
关键词
-
出版物
ONCOGENE
Volume 32, Issue 7, Pages 805-818
出版商
Springer Nature
发表日期
2012-04-16
DOI
10.1038/onc.2012.130
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Chaperone-Targeting Cytotoxin and Endoplasmic Reticulum Stress-Inducing Drug Synergize to Kill Cancer Cells
- (2015) Joseph M. Backer et al. NEOPLASIA
- Regulation of G1 Arrest and Apoptosis in Hypoxia by PERK and GCN2-Mediated eIF2α Phosphorylation
- (2015) Yan Liu et al. NEOPLASIA
- ERP57 Membrane Translocation Dictates the Immunogenicity of Tumor Cell Death by Controlling the Membrane Translocation of Calreticulin
- (2014) M. Obeid JOURNAL OF IMMUNOLOGY
- X Box-Binding Protein 1 Regulates Angiogenesis in Human Pancreatic Adenocarcinomas
- (2014) Lorenzo Romero-Ramirez et al. Translational Oncology
- Beyond the endoplasmic reticulum: atypical GRP78 in cell viability, signalling and therapeutic targeting
- (2011) Min Ni et al. BIOCHEMICAL JOURNAL
- Inducible knockout of GRP78/BiP in the hematopoietic system suppresses Pten-null leukemogenesis and AKT oncogenic signaling
- (2011) S. Wey et al. BLOOD
- Protein disulfide isomerase blocks CEBPA translation and is up-regulated during the unfolded protein response in AML
- (2011) S. Haefliger et al. BLOOD
- Inducing apoptosis in chemotherapy-resistant B-lineage acute lymphoblastic leukaemia cells by targeting HSPA5, a master regulator of the anti-apoptotic unfolded protein response signalling network
- (2011) Fatih M. Uckun et al. BRITISH JOURNAL OF HAEMATOLOGY
- Virus-Tumor Interactome Screen Reveals ER Stress Response Can Reprogram Resistant Cancers for Oncolytic Virus-Triggered Caspase-2 Cell Death
- (2011) Douglas J. Mahoney et al. CANCER CELL
- Exploiting Cancer Cell Vulnerabilities to Develop a Combination Therapy for Ras-Driven Tumors
- (2011) Thomas De Raedt et al. CANCER CELL
- A Critical Role for GRP78/BiP in the Tumor Microenvironment for Neovascularization during Tumor Growth and Metastasis
- (2011) D. Dong et al. CANCER RESEARCH
- Autophagy and BiP level decrease are early key events in retrograde degeneration of motoneurons
- (2011) C Penas et al. CELL DEATH AND DIFFERENTIATION
- Cripto Regulates Hematopoietic Stem Cells as a Hypoxic-Niche-Related Factor through Cell Surface Receptor GRP78
- (2011) Kenichi Miharada et al. Cell Stem Cell
- Comparison of adjuvant activity of N- and C-terminal domain of gp96 in a Her2-positive breast cancer model
- (2011) Nafiseh Pakravan et al. CELL STRESS & CHAPERONES
- The immunological era in melanoma treatment: new challenges for heat shock protein-based vaccine in the advanced disease
- (2011) Alessandra di Pietro et al. EXPERT OPINION ON BIOLOGICAL THERAPY
- The Cell Biology of the Unfolded Protein Response
- (2011) J. Alan Diehl et al. GASTROENTEROLOGY
- Novel Mechanism of Anti-apoptotic Function of 78-kDa Glucose-regulated Protein (GRP78)
- (2011) Hui Zhou et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Antitumor activity of mixed heat shock protein/peptide vaccine and cyclophosphamide plus interleukin-12 in mice sarcoma
- (2011) Quan-Yi Guo et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- CD204 Suppresses Large Heat Shock Protein-Facilitated Priming of Tumor Antigen gp100-Specific T Cells and Chaperone Vaccine Activity against Mouse Melanoma
- (2011) J. Qian et al. JOURNAL OF IMMUNOLOGY
- Tumor-Produced Secreted Form of Binding of Immunoglobulin Protein Elicits Antigen-Specific Tumor Immunity
- (2011) Yasuaki Tamura et al. JOURNAL OF IMMUNOLOGY
- PERK Integrates Autophagy and Oxidative Stress Responses To Promote Survival during Extracellular Matrix Detachment
- (2011) A. Avivar-Valderas et al. MOLECULAR AND CELLULAR BIOLOGY
- The eIF2 kinase PERK and the integrated stress response facilitate activation of ATF6 during endoplasmic reticulum stress
- (2011) Brian F. Teske et al. MOLECULAR BIOLOGY OF THE CELL
- Transmission of endoplasmic reticulum stress and pro-inflammation from tumor cells to myeloid cells
- (2011) N. R. Mahadevan et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Surface-exposed calreticulin in the interaction between dying cells and phagocytes
- (2010) Isabelle Martins et al. Annals of the New York Academy of Sciences
- The Hsp90 inhibitor IPI-504 overcomes bortezomib resistance in mantle cell lymphoma in vitro and in vivo by down-regulation of the prosurvival ER chaperone BiP/Grp78
- (2010) G. Roue et al. BLOOD
- Novel targets for endoplasmic reticulum stress-induced apoptosis in B-CLL
- (2010) E. Rosati et al. BLOOD
- Identification of an Ire1alpha endonuclease specific inhibitor with cytotoxic activity against human multiple myeloma
- (2010) I. Papandreou et al. BLOOD
- Ligation of cell surface GRP78 with antibody directed against the COOH-terminal domain of GRP78 suppresses Ras/MAPK and PI 3-kinase/AKT signaling while promoting caspase activation in human prostate cancer cells
- (2010) Uma K. Misra et al. CANCER BIOLOGY & THERAPY
- Heat shock protein 110 improves the anti-tumor effects of the cytotoxic T lymphocyte epitope E7 in mice
- (2010) Faliang Ren et al. CANCER BIOLOGY & THERAPY
- Adjuvant activity of GP96 C-terminal domain towards Her2/neu DNA vaccine is fusion direction-dependent
- (2010) Nafiseh Pakravan et al. CELL STRESS & CHAPERONES
- The critical role of GRP78 in physiologic and pathologic stress
- (2010) Kyle T Pfaffenbach et al. CURRENT OPINION IN CELL BIOLOGY
- The GCN2-ATF4 pathway is critical for tumour cell survival and proliferation in response to nutrient deprivation
- (2010) Jiangbin Ye et al. EMBO JOURNAL
- Cancer antineovascular therapy with liposome drug delivery systems targeted to BiP/GRP78
- (2010) Yasufumi Katanasaka et al. INTERNATIONAL JOURNAL OF CANCER
- Cell Surface Relocalization of the Endoplasmic Reticulum Chaperone and Unfolded Protein Response Regulator GRP78/BiP
- (2010) Yi Zhang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Ligation of Prostate Cancer Cell Surface GRP78 Activates a Proproliferative and Antiapoptotic Feedback Loop
- (2010) Uma K. Misra et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Superior Antitumor Response Induced by Large Stress Protein Chaperoned Protein Antigen Compared with Peptide Antigen
- (2010) X. Y. Wang et al. JOURNAL OF IMMUNOLOGY
- GRP78 up-regulation is associated with androgen receptor status, Hsp70-Hsp90 client proteins and castrate-resistant prostate cancer
- (2010) Shaun S Tan et al. JOURNAL OF PATHOLOGY
- Discovery of a Novel Unfolded Protein Response Phenotype of Cancer Stem/Progenitor Cells from the Bone Marrow of Breast Cancer Patients
- (2010) Kai Bartkowiak et al. JOURNAL OF PROTEOME RESEARCH
- Autologous tumor-derived heat-shock protein peptide complex-96 (HSPPC-96) in patients with metastatic melanoma
- (2010) Omar Eton et al. Journal of Translational Medicine
- Overexpressing GRP78 influences Ca2+ handling and function of mitochondria in astrocytes after ischemia-like stress
- (2010) Yi-Bing Ouyang et al. MITOCHONDRION
- Elimination of head and neck cancer initiating cells through targeting glucose regulated protein78 signaling
- (2010) Meng-Ju Wu et al. Molecular Cancer
- Endoplasmic reticulum stress mediates radiation-induced autophagy by perk-eIF2α in caspase-3/7-deficient cells
- (2010) K W Kim et al. ONCOGENE
- Regulation of autophagy by ATF4 in response to severe hypoxia
- (2010) T Rzymski et al. ONCOGENE
- PERK promotes cancer cell proliferation and tumor growth by limiting oxidative DNA damage
- (2010) E Bobrovnikova-Marjon et al. ONCOGENE
- Restoration of the immunogenicity of cisplatin-induced cancer cell death by endoplasmic reticulum stress
- (2010) I Martins et al. ONCOGENE
- Targeting GRP78 to enhance melanoma cell death
- (2010) Shaun Martin et al. Pigment Cell & Melanoma Research
- Transcriptional Regulation of VEGF-A by the Unfolded Protein Response Pathway
- (2010) Rajarshi Ghosh et al. PLoS One
- Transcriptional and Post-Transcriptional Regulation of Proangiogenic Factors by the Unfolded Protein Response
- (2010) Ethel R. Pereira et al. PLoS One
- Inositol-requiring enzyme 1 is a key regulator of angiogenesis and invasion in malignant glioma
- (2010) G. Auf et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Calreticulin Is the Dominant Pro-Phagocytic Signal on Multiple Human Cancers and Is Counterbalanced by CD47
- (2010) M. P. Chao et al. Science Translational Medicine
- Calreticulin exposure on malignant blasts predicts a cellular anticancer immune response in patients with acute myeloid leukemia
- (2010) M Wemeau et al. Cell Death & Disease
- XBP1: the last two decades
- (2009) L H Glimcher ANNALS OF THE RHEUMATIC DISEASES
- Role of the Unfolded Protein Response Regulator GRP78/BiP in Development, Cancer, and Neurological Disorders
- (2009) Miao Wang et al. ANTIOXIDANTS & REDOX SIGNALING
- GRP78: A Multifunctional Receptor on the Cell Surface
- (2009) Mario Gonzalez–Gronow et al. ANTIOXIDANTS & REDOX SIGNALING
- Calreticulin, a multi-process calcium-buffering chaperone of the endoplasmic reticulum
- (2009) Marek Michalak et al. BIOCHEMICAL JOURNAL
- GRP-78 secreted by tumor cells blocks the antiangiogenic activity of bortezomib
- (2009) J. Kern et al. BLOOD
- Myeloma cell line-derived, pooled heat shock proteins as a universal vaccine for immunotherapy of multiple myeloma
- (2009) J. Qian et al. BLOOD
- Accelerated Metastasis after Short-Term Treatment with a Potent Inhibitor of Tumor Angiogenesis
- (2009) John M.L. Ebos et al. CANCER CELL
- Antiangiogenic Therapy Elicits Malignant Progression of Tumors to Increased Local Invasion and Distant Metastasis
- (2009) Marta Pàez-Ribes et al. CANCER CELL
- Tumor-Induced Suppression of CTL Expansion and Subjugation by gp96-Ig Vaccination
- (2009) T. H. Schreiber et al. CANCER RESEARCH
- Endoplasmic Reticulum Stress Triggers XBP-1-Mediated Up-regulation of an EBV Oncoprotein in Nasopharyngeal Carcinoma
- (2009) J.-R. Hsiao et al. CANCER RESEARCH
- The Role of ATF4 Stabilization and Autophagy in Resistance of Breast Cancer Cells Treated with Bortezomib
- (2009) M. Milani et al. CANCER RESEARCH
- Inhibition of eIF2α Dephosphorylation Maximizes Bortezomib Efficiency and Eliminates Quiescent Multiple Myeloma Cells Surviving Proteasome Inhibitor Therapy
- (2009) Denis M. Schewe et al. CANCER RESEARCH
- IRE1α Kinase Activation Modes Control Alternate Endoribonuclease Outputs to Determine Divergent Cell Fates
- (2009) Dan Han et al. CELL
- IRE1α controls cyclin A1 expression and promotes cell proliferation through XBP-1
- (2009) Jeffery A. Thorpe et al. CELL STRESS & CHAPERONES
- Mechanisms of pre-apoptotic calreticulin exposure in immunogenic cell death
- (2009) Theocharis Panaretakis et al. EMBO JOURNAL
- Calreticulin: non-endoplasmic reticulum functions in physiology and disease
- (2009) Leslie I. Gold et al. FASEB JOURNAL
- Expression pattern of XBP1(S) in human B-cell lymphomas
- (2009) L. Maestre et al. HAEMATOLOGICA
- Expression of glucose-regulated stress protein GRP78 is related to progression of melanoma
- (2009) Liquing Zhuang et al. HISTOPATHOLOGY
- Regulated Ire1-dependent decay of messenger RNAs in mammalian cells
- (2009) Julie Hollien et al. JOURNAL OF CELL BIOLOGY
- The unfolded protein response protects human tumor cells during hypoxia through regulation of the autophagy genes MAP1LC3B and ATG5
- (2009) Kasper M.A. Rouschop et al. JOURNAL OF CLINICAL INVESTIGATION
- A Heat Shock Protein 70-Based Vaccine with Enhanced Immunogenicity for Clinical Use
- (2009) Jianlin Gong et al. JOURNAL OF IMMUNOLOGY
- The anti-apoptotic role of the unfolded protein response in Bcr-Abl-positive leukemia cells
- (2009) Atsuko Tanimura et al. LEUKEMIA RESEARCH
- Transcriptional induction of GRP78/BiP by histone deacetylase inhibitors and resistance to histone deacetylase inhibitor-induced apoptosis
- (2009) P. Baumeister et al. MOLECULAR CANCER THERAPEUTICS
- Regulation of PERK Signaling and Leukemic Cell Survival by a Novel Cytosolic Isoform of the UPR Regulator GRP78/BiP
- (2009) Min Ni et al. PLoS One
- PERK Regulates the Proliferation and Development of Insulin-Secreting Beta-Cell Tumors in the Endocrine Pancreas of Mice
- (2009) Sounak Gupta et al. PLoS One
- REVIEW ARTICLE: Secreted Heat Shock Protein gp96-Ig: An Innovative Vaccine Approach
- (2008) Natasa Strbo et al. AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY
- Natural and genetically engineered viral agents for oncolysis and gene therapy of human cancers
- (2008) Joseph G. Sinkovics et al. ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS
- Protein disulfide isomerases are antibody targets during immune-mediated tumor destruction
- (2008) C. Fonseca et al. BLOOD
- Increasing Melanoma Cell Death Using Inhibitors of Protein Disulfide Isomerases to Abrogate Survival Responses to Endoplasmic Reticulum Stress
- (2008) P. E. Lovat et al. CANCER RESEARCH
- Dual Function of Pancreatic Endoplasmic Reticulum Kinase in Tumor Cell Growth Arrest and Survival
- (2008) A. C. Ranganathan et al. CANCER RESEARCH
- Critical Role of the Stress Chaperone GRP78/BiP in Tumor Proliferation, Survival, and Tumor Angiogenesis in Transgene-Induced Mammary Tumor Development
- (2008) D. Dong et al. CANCER RESEARCH
- Preferential Cytotoxicity of Bortezomib toward Hypoxic Tumor Cells via Overactivation of Endoplasmic Reticulum Stress Pathways
- (2008) D. R. Fels et al. CANCER RESEARCH
- The co-translocation of ERp57 and calreticulin determines the immunogenicity of cell death
- (2008) T Panaretakis et al. CELL DEATH AND DIFFERENTIATION
- The unfolded protein response regulator GRP78/BiP is required for endoplasmic reticulum integrity and stress-induced autophagy in mammalian cells
- (2008) J Li et al. CELL DEATH AND DIFFERENTIATION
- Expression and splicing of the unfolded protein response gene XBP-1 are significantly associated with clinical outcome of endocrine-treated breast cancer
- (2008) Michael P.A. Davies et al. INTERNATIONAL JOURNAL OF CANCER
- Getting In and Out from Calnexin/Calreticulin Cycles
- (2008) Julio J. Caramelo et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Synergistic promotion of breast cancer cells death by targeting molecular chaperone GRP78 and heat shock protein 70
- (2008) Minjing Li et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- PERK is essential for neonatal skeletal development to regulate osteoblast proliferation and differentiation
- (2008) Jianwen Wei et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Phase III Comparison of Vitespen, an Autologous Tumor-Derived Heat Shock Protein gp96 Peptide Complex Vaccine, With Physician's Choice of Treatment for Stage IV Melanoma: The C-100-21 Study Group
- (2008) Alessandro Testori et al. JOURNAL OF CLINICAL ONCOLOGY
- A new tumor-specific variant of GRP78 as target for antibody-based therapy
- (2008) Nicole Rauschert et al. LABORATORY INVESTIGATION
- An adjuvant autologous therapeutic vaccine (HSPPC-96; vitespen) versus observation alone for patients at high risk of recurrence after nephrectomy for renal cell carcinoma: a multicentre, open-label, randomised phase III trial
- (2008) Christopher Wood et al. LANCET
- Tumor Hypoxia Blocks Wnt Processing and Secretion through the Induction of Endoplasmic Reticulum Stress
- (2008) M. Verras et al. MOLECULAR AND CELLULAR BIOLOGY
- Stress Chaperone GRP78/BiP Confers Chemoresistance to Tumor-Associated Endothelial Cells
- (2008) J. J. Virrey et al. MOLECULAR CANCER RESEARCH
- Pyrvinium Targets the Unfolded Protein Response to Hypoglycemia and Its Anti-Tumor Activity Is Enhanced by Combination Therapy
- (2008) De-Hua Yu et al. PLoS One
- Pten null prostate tumorigenesis and AKT activation are blocked by targeted knockout of ER chaperone GRP78/BiP in prostate epithelium
- (2008) Y. Fu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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