Cell biology of diabetic nephropathy: Roles of endothelial cells, tubulointerstitial cells and podocytes

Endothelial mitochondrial oxidative stress determines podocyte depletion in segmental glomerulosclerosis

(2014) Ilse Daehn et al.   JOURNAL OF CLINICAL INVESTIGATION

Vascular Complications of Diabetes: Mechanisms of Injury and Protective Factors

(2013) Christian Rask-Madsen et al.   Cell Metabolism

Urinary and glomerular podocytes in patients with chronic kidney diseases

(2013) Kikuno Hanamura et al.   Clinical and Experimental Nephrology

Atorvastatin ameliorates podocyte injury in patients with type 2 diabetes complicated with dyslipidemia

(2013) Minoru Takemoto et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

Targeted Glomerular Angiopoietin-1 Therapy for Early Diabetic Kidney Disease

(2013) C. Dessapt-Baradez et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Rho-kinase inhibition prevents the progression of diabetic nephropathy by downregulating hypoxia-inducible factor 1α

(2013) Keiichiro Matoba et al.   KIDNEY INTERNATIONAL

AKT2 is essential to maintain podocyte viability and function during chronic kidney disease

(2013) Guillaume Canaud et al.   NATURE MEDICINE

Renal tubular Sirt1 attenuates diabetic albuminuria by epigenetically suppressing Claudin-1 overexpression in podocytes

(2013) Kazuhiro Hasegawa et al.   NATURE MEDICINE

Origin and function of myofibroblasts in kidney fibrosis

(2013) Valerie S LeBleu et al.   NATURE MEDICINE

Mechanisms of Diabetic Complications

(2013) Josephine M. Forbes et al.   PHYSIOLOGICAL REVIEWS

Soluble FLT1 Binds Lipid Microdomains in Podocytes to Control Cell Morphology and Glomerular Barrier Function

(2012) Jing Jin et al.   CELL

mTOR Signaling in Growth Control and Disease

(2012) Mathieu Laplante et al.   CELL

Vegfa Protects the Glomerular Microvasculature in Diabetes

(2012) G. A. Sivaskandarajah et al.   DIABETES

Notch pathway is involved in high glucose-induced apoptosis in podocytes via Bcl-2 and p53 pathways

(2012) Feng Gao et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Diabetic Nephropathy and Extracellular Matrix

(2012) S. O. Kolset et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

Podocyte-Specific Loss of Cdc42 Leads to Congenital Nephropathy

(2012) R. P. Scott et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

The glomerular endothelium emerges as a key player in diabetic nephropathy

(2012) Simon C. Satchell   KIDNEY INTERNATIONAL

Podocyte detachment and reduced glomerular capillary endothelial fenestration promote kidney disease in type 2 diabetic nephropathy

(2012) E. Jennifer Weil et al.   KIDNEY INTERNATIONAL

Can We Target Tubular Damage to Prevent Renal Function Decline in Diabetes?

(2012) Joseph V. Bonventre   SEMINARS IN NEPHROLOGY

Notch Signaling

(2012) R. Kopan   Cold Spring Harbor Perspectives in Biology

Cell Biology and Pathology of Podocytes

(2011) Anna Greka et al.   Annual Review of Physiology

Dedifferentiation of Immortalized Human Podocytes in Response to Transforming Growth Factor- : A Model for Diabetic Podocytopathy

(2011) M. Herman-Edelstein et al.   DIABETES

Podocyte vascular endothelial growth factor (Vegf 164 ) overexpression causes severe nodular glomerulosclerosis in a mouse model of type 1 diabetes

(2011) D. Veron et al.   DIABETOLOGIA

Angiopoietin-1 is essential in mouse vasculature during development and in response to injury

(2011) Marie Jeansson et al.   JOURNAL OF CLINICAL INVESTIGATION

Role of mTOR in podocyte function and diabetic nephropathy in humans and mice

(2011) Markus Gödel et al.   JOURNAL OF CLINICAL INVESTIGATION

mTORC1 activation in podocytes is a critical step in the development of diabetic nephropathy in mice

(2011) Ken Inoki et al.   JOURNAL OF CLINICAL INVESTIGATION

Endothelial glycocalyx dysfunction in disease: albuminuria and increased microvascular permeability

(2011) Andrew HJ Salmon et al.   JOURNAL OF PATHOLOGY

Inhibition of MTOR Disrupts Autophagic Flux in Podocytes

(2011) D. P. Cina et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Activation of RhoA in Podocytes Induces Focal Segmental Glomerulosclerosis

(2011) L. Zhu et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

The glomerular endothelial cell coat is essential for glomerular filtration

(2011) Vincent Fridén et al.   KIDNEY INTERNATIONAL

Tubular Overexpression of Transforming Growth Factor-β1 Induces Autophagy and Fibrosis but Not Mesenchymal Transition of Renal Epithelial Cells

(2010) Robert Koesters et al.   AMERICAN JOURNAL OF PATHOLOGY

Insulin Signaling to the Glomerular Podocyte Is Critical for Normal Kidney Function

(2010) Gavin I. Welsh et al.   Cell Metabolism

Blockade of Endothelial-Mesenchymal Transition by a Smad3 Inhibitor Delays the Early Development of Streptozotocin-Induced Diabetic Nephropathy

(2010) J. Li et al.   DIABETES

The Protective Role of Smad7 in Diabetic Kidney Disease: Mechanism and Therapeutic Potential

(2010) H. Y. Chen et al.   DIABETES

Deterioration of glomerular endothelial surface layer induced by oxidative stress is implicated in altered permeability of macromolecules in Zucker fatty rats

(2010) A. Kuwabara et al.   DIABETOLOGIA

Effect of sulodexide on endothelial glycocalyx and vascular permeability in patients with type 2 diabetes mellitus

(2010) L. N. Broekhuizen et al.   DIABETOLOGIA

The MicroRNA-Processing Enzyme Dicer Maintains Juxtaglomerular Cells

(2010) M. L. S. Sequeira-Lopez et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Rho kinase inhibition protects kidneys from diabetic nephropathy without reducing blood pressure

(2010) Radko Komers et al.   KIDNEY INTERNATIONAL

In VivoVisualization of Glomerular Microcirculation and Hyperfiltration in Streptozotocin-Induced Diabetic Rats

(2010) MINORU SATOH et al.   MICROCIRCULATION

Endothelial dysfunction as a potential contributor in diabetic nephropathy

(2010) Takahiko Nakagawa et al.   Nature Reviews Nephrology

Diabetic kidney disease: act now or pay later

(2010) R. C. Atkins et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Endothelial Surface Layer Degradation by Chronic Hyaluronidase Infusion Induces Proteinuria in Apolipoprotein E-Deficient Mice

(2010) Marijn C. Meuwese et al.   PLoS One

Effects of Increased Renal Tubular Vascular Endothelial Growth Factor (VEGF) on Fibrosis, Cyst Formation, and Glomerular Disease

(2009) Samy Hakroush et al.   AMERICAN JOURNAL OF PATHOLOGY

Lowering Blood Pressure Blocks Mesangiolysis and Mesangial Nodules, but Not Tubulointerstitial Injury, in Diabetic eNOS Knockout Mice

(2009) Tomoki Kosugi et al.   AMERICAN JOURNAL OF PATHOLOGY

Wnt/ -Catenin Signaling Promotes Podocyte Dysfunction and Albuminuria

(2009) C. Dai et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Angiopoietin 2 Is a Partial Agonist/Antagonist of Tie2 Signaling in the Endothelium

(2009) H. T. Yuan et al.   MOLECULAR AND CELLULAR BIOLOGY

The Pharmacology of mTOR Inhibition

(2009) D. A. Guertin et al.   Science Signaling

Angiotensin II Infusion Induces Nephrin Expression Changes and Podocyte Apoptosis

(2008) Junya Jia et al.   AMERICAN JOURNAL OF NEPHROLOGY

Inducible Overexpression of sFlt-1 in Podocytes Ameliorates Glomerulopathy in Diabetic Mice

(2008) C.-H. Ku et al.   DIABETES

Fibroblasts in Kidney Fibrosis Emerge via Endothelial-to-Mesenchymal Transition

(2008) E. M. Zeisberg et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Adriamycin Alters Glomerular Endothelium to Induce Proteinuria

(2008) M. Jeansson et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Phosphorylated YDXV Motifs and Nck SH2/SH3 Adaptors Act Cooperatively To Induce Actin Reorganization

(2008) I. M. Blasutig et al.   MOLECULAR AND CELLULAR BIOLOGY

The Notch pathway in podocytes plays a role in the development of glomerular disease

(2008) Thiruvur Niranjan et al.   NATURE MEDICINE

Prevalence of atubular glomeruli in type 2 diabetic patients with nephropathy

(2008) K. E. White et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Properties of the Glomerular Barrier and Mechanisms of Proteinuria

(2008) Börje Haraldsson et al.   PHYSIOLOGICAL REVIEWS