AKT2 is essential to maintain podocyte viability and function during chronic kidney disease

Podocyte-Specific Loss of Cdc42 Leads to Congenital Nephropathy

(2012) R. P. Scott et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Associations of kidney disease measures with mortality and end-stage renal disease in individuals with and without hypertension: a meta-analysis

(2012) Bakhtawar K Mahmoodi et al.   LANCET

Insulin regulates liver metabolism in vivo in the absence of hepatic Akt and Foxo1

(2012) Mingjian Lu et al.   NATURE MEDICINE

Rapamycin-Induced Insulin Resistance Is Mediated by mTORC2 Loss and Uncoupled from Longevity

(2012) D. W. Lamming et al.   SCIENCE

Arhgap24 inactivates Rac1 in mouse podocytes, and a mutant form is associated with familial focal segmental glomerulosclerosis

(2011) Shreeram Akilesh et al.   JOURNAL OF CLINICAL INVESTIGATION

Role of mTOR in podocyte function and diabetic nephropathy in humans and mice

(2011) Markus Gödel et al.   JOURNAL OF CLINICAL INVESTIGATION

mTORC1 activation in podocytes is a critical step in the development of diabetic nephropathy in mice

(2011) Ken Inoki et al.   JOURNAL OF CLINICAL INVESTIGATION

mTORC1 activation triggers the unfolded protein response in podocytes and leads to nephrotic syndrome

(2011) Noriko Ito et al.   LABORATORY INVESTIGATION

Insulin Signaling to the Glomerular Podocyte Is Critical for Normal Kidney Function

(2010) Gavin I. Welsh et al.   Cell Metabolism

Mechanical stretch and prostaglandin E2 modulate critical signaling pathways in mouse podocytes

(2010) Wissam H. Faour et al.   CELLULAR SIGNALLING

Lipocalin 2 is essential for chronic kidney disease progression in mice and humans

(2010) Amandine Viau et al.   JOURNAL OF CLINICAL INVESTIGATION

TGF-  Mediates Genetic Susceptibility to Chronic Kidney Disease

(2010) D. Laouari et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Inhibition of Podocyte FAK Protects against Proteinuria and Foot Process Effacement

(2010) H. Ma et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

The PI3K/Akt/mTOR pathway is activated in murine lupus nephritis and downregulated by rapamycin

(2010) Kostas Stylianou et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Podocin Inactivation in Mature Kidneys Causes Focal Segmental Glomerulosclerosis and Nephrotic Syndrome

(2009) G. Mollet et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Wnt/ -Catenin Signaling Promotes Podocyte Dysfunction and Albuminuria

(2009) C. Dai et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Proteinuria: an enzymatic disease of the podocyte?

(2009) Peter Mundel et al.   KIDNEY INTERNATIONAL

Signaling in Regulation of Podocyte Phenotypes

(2009) Peter Y. Chuang et al.   NEPHRON PHYSIOLOGY

Banff 07 Classification of Renal Allograft Pathology: Updates and Future Directions

(2008) K. Solez et al.   AMERICAN JOURNAL OF TRANSPLANTATION

The PI3K/Akt Pathway: Recent Progress in the Development of ATP-Competitive and Allosteric Akt Kinase Inhibitors

(2008) Craig Lindsley et al.   CURRENT CANCER DRUG TARGETS

Failure to phosphorylate AKT in podocytes from mice with early diabetic nephropathy promotes cell death

(2008) T. Tejada et al.   KIDNEY INTERNATIONAL

Modification of mineralocorticoid receptor function by Rac1 GTPase: implication in proteinuric kidney disease

(2008) Shigeru Shibata et al.   NATURE MEDICINE

The Notch pathway in podocytes plays a role in the development of glomerular disease

(2008) Thiruvur Niranjan et al.   NATURE MEDICINE

The actin cytoskeleton of kidney podocytes is a direct target of the antiproteinuric effect of cyclosporine A

(2008) Christian Faul et al.   NATURE MEDICINE

Sirolimus interacts with pathways essential for podocyte integrity

(2008) E. Letavernier et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Intracellular Signaling by Akt: Bound to Be Specific

(2008) T. F. Franke   Science Signaling

Nephrin mediates actin reorganization via phosphoinositide 3-kinase in podocytes

(2007) J. Zhu et al.   KIDNEY INTERNATIONAL