Role of mTOR in podocyte function and diabetic nephropathy in humans and mice

mTORC1 activation in podocytes is a critical step in the development of diabetic nephropathy in mice

(2011) Ken Inoki et al.   JOURNAL OF CLINICAL INVESTIGATION

Insulin Signaling to the Glomerular Podocyte Is Critical for Normal Kidney Function

(2010) Gavin I. Welsh et al.   Cell Metabolism

The story of Notch and chronic kidney disease

(2010) Shuchita Sharma et al.   CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION

Epithelial Notch signaling regulates interstitial fibrosis development in the kidneys of mice and humans

(2010) Bernhard Bielesz et al.   JOURNAL OF CLINICAL INVESTIGATION

Autophagy influences glomerular disease susceptibility and maintains podocyte homeostasis in aging mice

(2010) Björn Hartleben et al.   JOURNAL OF CLINICAL INVESTIGATION

The mTOR pathway is highly activated in diabetic nephropathy and rapamycin has a strong therapeutic potential

(2009) Hiroyuki Mori et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

mTOR and the control of whole body metabolism

(2009) Pazit Polak et al.   CURRENT OPINION IN CELL BIOLOGY

mTOR signaling at a glance

(2009) M. Laplante et al.   JOURNAL OF CELL SCIENCE

Significance and Management of Proteinuria in Kidney Transplant Recipients

(2009) H. Amer et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

The Role of the Mammalian Target Of Rapamycin (mTOR) in Renal Disease

(2009) W. Lieberthal et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Nck Proteins Maintain the Adult Glomerular Filtration Barrier

(2009) N. Jones et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Rapamycin has dual opposing effects on proteinuric experimental nephropathies: is it a matter of podocyte damage?

(2009) J. Torras et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Adipose-Specific Knockout of raptor Results in Lean Mice with Enhanced Mitochondrial Respiration

(2008) Pazit Polak et al.   Cell Metabolism

Skeletal Muscle-Specific Ablation of raptor, but Not of rictor, Causes Metabolic Changes and Results in Muscle Dystrophy

(2008) C. Florian Bentzinger et al.   Cell Metabolism

Enhanced Expression of Janus Kinase-Signal Transducer and Activator of Transcription Pathway Members in Human Diabetic Nephropathy

(2008) C. C. Berthier et al.   DIABETES

Role of TSC–mTOR pathway in diabetic nephropathy

(2008) Ken Inoki   DIABETES RESEARCH AND CLINICAL PRACTICE

Tuberous sclerosis complex proteins control axon formation

(2008) Y.-J. Choi et al.   GENES & DEVELOPMENT

The Notch pathway in podocytes plays a role in the development of glomerular disease

(2008) Thiruvur Niranjan et al.   NATURE MEDICINE

VEGF Inhibition and Renal Thrombotic Microangiopathy

(2008) Vera Eremina et al.   NEW ENGLAND JOURNAL OF MEDICINE

Improved Elucidation of Biological Processes Linked to Diabetic Nephropathy by Single Probe-Based Microarray Data Analysis

(2008) Clemens D. Cohen et al.   PLoS One