A Wnt-TGF 2 axis induces a fibrogenic program in muscle stem cells from dystrophic mice

Critical role of Frizzled1 in age-related alterations of Wnt/β-catenin signal in myogenic cells during differentiation

(2014) Ryosuke Doi et al.   GENES TO CELLS

Aging increases CCN1 expression leading to muscle senescence

(2013) Jie Du et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Satellite cells isolated from aged or dystrophic muscle exhibit a reduced capacity to promote angiogenesis in vitro

(2013) R.P. Rhoads et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Myf5 expression during fetal myogenesis defines the developmental progenitors of adult satellite cells

(2013) Stefano Biressi et al.   DEVELOPMENTAL BIOLOGY

Muscular dystrophies

(2013) Eugenio Mercuri et al.   LANCET

Origin and function of myofibroblasts in kidney fibrosis

(2013) Valerie S LeBleu et al.   NATURE MEDICINE

Activation of β-catenin/TCF targets following loss of the tumor suppressor SNF5

(2013) E L Mora-Blanco et al.   ONCOGENE

Wnt/β-catenin signaling is hyperactivated in systemic sclerosis and induces Smad-dependent fibrotic responses in mesenchymal cells

(2012) Jun Wei et al.   ARTHRITIS AND RHEUMATISM

Complement C1q Activates Canonical Wnt Signaling and Promotes Aging-Related Phenotypes

(2012) Atsuhiko T. Naito et al.   CELL

Wnt/β-Catenin Signaling and Disease

(2012) Hans Clevers et al.   CELL

Function of Wnt/ -catenin in counteracting Tcf3 repression through the Tcf3- -catenin interaction

(2012) C.-I. Wu et al.   DEVELOPMENT

Lineage tracing and genetic ablation of ADAM12+ perivascular cells identify a major source of profibrotic cells during acute tissue injury

(2012) Sophie Dulauroy et al.   NATURE MEDICINE

Targeting the TGFβ signalling pathway in disease

(2012) Rosemary J. Akhurst et al.   NATURE REVIEWS DRUG DISCOVERY

Activation of canonical Wnt signalling is required for TGF-β-mediated fibrosis

(2012) Alfiya Akhmetshina et al.   Nature Communications

Heat Shock Protein 47: A Novel Biomarker of Phenotypically Altered Collagen-Producing Cells

(2011) Takashi Taguchi et al.   ACTA HISTOCHEMICA ET CYTOCHEMICA

Inhibiting TGF-β Activity Improves Respiratory Function in mdx Mice

(2011) Carol A. Nelson et al.   AMERICAN JOURNAL OF PATHOLOGY

Satellite cells, connective tissue fibroblasts and their interactions are crucial for muscle regeneration

(2011) M. M. Murphy et al.   DEVELOPMENT

Pax7-expressing satellite cells are indispensable for adult skeletal muscle regeneration

(2011) R. Sambasivan et al.   DEVELOPMENT

An absolute requirement for Pax7-positive satellite cells in acute injury-induced skeletal muscle regeneration

(2011) C. Lepper et al.   DEVELOPMENT

Fibrosis and adipogenesis originate from a common mesenchymal progenitor in skeletal muscle

(2011) A. Uezumi et al.   JOURNAL OF CELL SCIENCE

TGF-β regulates β-catenin signaling and osteoblast differentiation in human mesenchymal stem cells

(2011) Shuanhu Zhou   JOURNAL OF CELLULAR BIOCHEMISTRY

 -Catenin Causes Renal Dysplasia via Upregulation of Tgf 2 and Dkk1

(2011) D. Bridgewater et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Sca-1-Expressing Nonmyogenic Cells Contribute to Fibrosis in Aged Skeletal Muscle

(2011) M. Hidestrand et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Wnt3a Induces Myofibroblast Differentiation by Upregulating TGF-β Signaling Through SMAD2 in a β-Catenin-Dependent Manner

(2011) Jon M. Carthy et al.   PLoS One

Genetic Background Affects Properties of Satellite Cells and mdx Phenotypes

(2010) So-ichiro Fukada et al.   AMERICAN JOURNAL OF PATHOLOGY

A muscle resident cell population promotes fibrosis in hindlimb skeletal muscles of mdx mice through the Wnt canonical pathway

(2010) Frédéric Trensz et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Short Telomeres and Stem Cell Exhaustion Model Duchenne Muscular Dystrophy in mdx/mTR Mice

(2010) Alessandra Sacco et al.   CELL

Direct effects of the pathogenic mutation on satellite cell function in muscular dystrophy

(2010) Jennifer E. Morgan et al.   EXPERIMENTAL CELL RESEARCH

Muscle injury activates resident fibro/adipogenic progenitors that facilitate myogenesis

(2010) Aaron W. B. Joe et al.   NATURE CELL BIOLOGY

Lentiviral Vectors to Probe and Manipulate the Wnt Signaling Pathway

(2010) Christophe Fuerer et al.   PLoS One

Identifying a High Fraction of the Human Genome to be under Selective Constraint Using GERP++

(2010) Eugene V. Davydov et al.   PLoS Computational Biology

Relative roles of TGF-β1 and Wnt in the systemic regulation and aging of satellite cell responses

(2009) Morgan E. Carlson et al.   AGING CELL

Endothelial-Myofibroblast Transition Contributes to the Early Development of Diabetic Renal Interstitial Fibrosis in Streptozotocin-Induced Diabetic Mice

(2009) Jinhua Li et al.   AMERICAN JOURNAL OF PATHOLOGY

Biomarker system for studying muscle, stem cells, and cancer in vivo

(2009) Koichi Nishijo et al.   FASEB JOURNAL

Focal Adhesion Kinase Signaling Regulates the Expression of Caveolin 3 and β1 Integrin, Genes Essential for Normal Myoblast Fusion

(2009) Navaline L. Quach et al.   MOLECULAR BIOLOGY OF THE CELL

Pericytes and Perivascular Fibroblasts Are the Primary Source of Collagen-Producing Cells in Obstructive Fibrosis of the Kidney

(2008) Shuei-Liong Lin et al.   AMERICAN JOURNAL OF PATHOLOGY

Mechanisms of Muscle Degeneration, Regeneration, and Repair in the Muscular Dystrophies

(2008) Gregory Q. Wallace et al.   Annual Review of Physiology

Axin and GSK3- control Smad3 protein stability and modulate TGF- signaling

(2008) X. Guo et al.   GENES & DEVELOPMENT

Fibrinogen drives dystrophic muscle fibrosis via a TGF /alternative macrophage activation pathway

(2008) B. Vidal et al.   GENES & DEVELOPMENT

A highly conserved molecular switch binds MSY-3 to regulate myogenin repression in postnatal muscle

(2008) L. Berghella et al.   GENES & DEVELOPMENT

Fibroblasts in Kidney Fibrosis Emerge via Endothelial-to-Mesenchymal Transition

(2008) E. M. Zeisberg et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

PlGF–MMP-9–expressing cells restore microcirculation and efficacy of cell therapy in aged dystrophic muscle

(2008) Cesare Gargioli et al.   NATURE MEDICINE