Prion Protein-Specific Antibodies that Detect Multiple TSE Agents with High Sensitivity

The PrPC C1 fragment derived from the ovine A136R154R171 PRNP allele is highly abundant in sheep brain and inhibits fibrillisation of full-length PrPC protein in vitro

(2013) Lauren Campbell et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Small Ruminant Nor98 Prions Share Biochemical Features with Human Gerstmann-Sträussler-Scheinker Disease and Variably Protease-Sensitive Prionopathy

(2013) Laura Pirisinu et al.   PLoS One

Binding of bovine T194A PrPCby PrPSc-specific antibodies

(2013) Claudia A Madampage et al.   Prion

Novel Epitopes Identified by Anti-PrP Monoclonal Antibodies Produced Following Immunization of Prnp0/0 Balb/cJ Mice with Purified Scrapie Prions

(2012) Larry H. Stanker et al.   HYBRIDOMA

Significant differences in incubation times in sheep infected with bovine spongiform encephalopathy result from variation at codon 141 in the PRNP gene

(2012) B. C. Tan et al.   JOURNAL OF GENERAL VIROLOGY

All major prion types recognised by a multiplex immunofluorometric assay for disease screening and confirmation in sheep

(2012) Yue Tang et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Immunotherapy in prion disease

(2012) Yvonne Roettger et al.   Nature Reviews Neurology

Using small molecule reagents to selectively modify epitopes based on their conformation

(2012) Christopher J. Silva   Prion

PrP Antibodies Do Not Trigger Mouse Hippocampal Neuron Apoptosis

(2012) P.-C. Klohn et al.   SCIENCE

Proteinase K-Resistant Material in ARR/VRQ Sheep Brain Affected with Classical Scrapie Is Composed Mainly of VRQ Prion Protein

(2011) J. G. Jacobs et al.   JOURNAL OF VIROLOGY

All Clinically-Relevant Blood Components Transmit Prion Disease following a Single Blood Transfusion: A Sheep Model of vCJD

(2011) Sandra McCutcheon et al.   PLoS One

Inverse Correlation of Thermal Lability and Conversion Efficiency for Five Prion Protein Polymorphic Variants

(2010) Louise Kirby et al.   BIOCHEMISTRY

A novel form of human disease with a protease-sensitive prion protein and heterozygosity methionine/valine at codon 129: Case report

(2010) Ana B Rodríguez-Martínez et al.   BMC Neurology

Immunomodulation for prion and prion-related diseases

(2010) Thomas Wisniewski et al.   Expert Review of Vaccines

Differentiation of ruminant transmissible spongiform encephalopathy isolate types, including bovine spongiform encephalopathy and CH1641 scrapie

(2010) J. G. Jacobs et al.   JOURNAL OF GENERAL VIROLOGY

A single step multiplex immunofluorometric assay for differential diagnosis of BSE and scrapie

(2010) Yue Tang et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Large-scale immunohistochemical examination for lymphoreticular prion protein in tonsil specimens collected in Britain

(2010) Mar Fernandez de Marco et al.   JOURNAL OF PATHOLOGY

Underestimation of the expression of cellular prion protein on human red blood cells

(2010) Martin Panigaj et al.   TRANSFUSION

A novel anti-prion protein monoclonal antibody and its single-chain fragment variable derivative with ability to inhibit abnormal prion protein accumulation in cultured cells

(2009) Yoshihisa Shimizu et al.   MICROBIOLOGY AND IMMUNOLOGY

Immunological mimicry of PrPC-PrPSc interactions: antibody-induced PrP misfolding

(2009) L. Li et al.   PROTEIN ENGINEERING DESIGN & SELECTION

Increase in CD230 (cellular prion protein) fluorescence on blood lymphocytes in bovine spongiform encephalopathy-infected nonhuman primates

(2009) Edgar Holznagel et al.   TRANSFUSION

Generation of monoclonal antibody that distinguishes PrPSc from PrPC and neutralizes prion infectivity

(2009) Motohiro Horiuchi et al.   VIROLOGY

The POM Monoclonals: A Comprehensive Set of Antibodies to Non-Overlapping Prion Protein Epitopes

(2008) Magdalini Polymenidou et al.   PLoS One

A C-Terminal Protease-Resistant Prion Fragment Distinguishes Ovine “CH1641-Like” Scrapie from Bovine Classical and L-Type BSE in Ovine Transgenic Mice

(2008) Thierry Baron et al.   PLoS Pathogens