标题
Cleavage of amyloid precursor protein by an archaeal presenilin homologue PSH
作者
关键词
-
出版物
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Volume 112, Issue 11, Pages 3344-3349
出版商
Proceedings of the National Academy of Sciences
发表日期
2015-03-03
DOI
10.1073/pnas.1502150112
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- AlphaLISA-based high-throughput screening assay to measure levels of soluble amyloid precursor protein α
- (2014) Hongjie Wang et al. ANALYTICAL BIOCHEMISTRY
- Alzheimer Presenilin-1 Mutations Dramatically Reduce Trimming of Long Amyloid β-Peptides (Aβ) by γ-Secretase to Increase 42-to-40-Residue Aβ
- (2014) Marty A. Fernandez et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Three-dimensional structure of human γ-secretase
- (2014) Peilong Lu et al. NATURE
- Crystal structure of the γ-secretase component nicastrin
- (2014) Tian Xie et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Molecular mechanism of the intramembrane cleavage of the β-carboxyl terminal fragment of amyloid precursor protein by γ-secretase
- (2014) Maho Morishima-Kawashima Frontiers in Physiology
- Development and Mechanism of γ-Secretase Modulators for Alzheimer’s Disease
- (2013) Christina J. Crump et al. BIOCHEMISTRY
- γ-Secretase inhibitors and modulators
- (2013) Todd E. Golde et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- Toward the structure of presenilin/γ-secretase and presenilin homologs
- (2013) Michael S. Wolfe BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- γ-Secretase Modulator (GSM) Photoaffinity Probes Reveal Distinct Allosteric Binding Sites on Presenilin
- (2013) Nikolay Pozdnyakov et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Signature Amyloid β Profiles Are Produced by Different γ-Secretase Complexes
- (2013) Hermien Acx et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Nicastrin Overexpression in Transgenic Mice Induces Aberrant Behavior and APP Processing
- (2013) Jun Seo Goo et al. MOLECULAR NEUROBIOLOGY
- Presenilins and -Secretase: Structure, Function, and Role in Alzheimer Disease
- (2013) B. De Strooper et al. Cold Spring Harbor Perspectives in Medicine
- The mechanism of γ-Secretase dysfunction in familial Alzheimer disease
- (2012) Lucía Chávez-Gutiérrez et al. EMBO JOURNAL
- Familial Alzheimer Disease Presenilin-1 Mutations Alter the Active Site Conformation of γ-secretase
- (2012) De-Ming Chau et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- First and Second Generation γ-Secretase Modulators (GSMs) Modulate Amyloid-β (Aβ) Peptide Production through Different Mechanisms
- (2012) Tomas Borgegard et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Structure of a presenilin family intramembrane aspartate protease
- (2012) Xiaochun Li et al. NATURE
- Piperidine Acetic Acid Based γ-Secretase Modulators Directly Bind to Presenilin-1
- (2011) Christina J. Crump et al. ACS Chemical Neuroscience
- Attenuated Aβ42Responses to Low Potency γ-Secretase Modulators Can Be Overcome for Many Pathogenic Presenilin Mutants by Second-generation Compounds
- (2011) Benedikt Kretner et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Twenty years of Alzheimer’s disease-causing mutations
- (2011) Alison Goate et al. JOURNAL OF NEUROCHEMISTRY
- Potent amyloidogenicity and pathogenicity of Aβ43
- (2011) Takashi Saito et al. NATURE NEUROSCIENCE
- Identification of an Archaeal Presenilin-Like Intramembrane Protease
- (2010) Celia Torres-Arancivia et al. PLoS One
- AlphaLISA Immunoassay Platform— The “No-Wash” High-Throughput Alternative to ELISA
- (2009) Martina Bielefeld-Sevigny ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES
- Glu-333 of Nicastrin Directly Participates in γ-Secretase Activity
- (2009) Daniel R. Dries et al. JOURNAL OF BIOLOGICAL CHEMISTRY
Create your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started