TGR5 reduces macrophage migration through mTOR-induced C/EBPβ differential translation
出版年份 2014 全文链接
标题
TGR5 reduces macrophage migration through mTOR-induced C/EBPβ differential translation
作者
关键词
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出版物
JOURNAL OF CLINICAL INVESTIGATION
Volume 124, Issue 12, Pages 5424-5436
出版商
American Society for Clinical Investigation
发表日期
2014-11-03
DOI
10.1172/jci76289
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Local Proliferation of Macrophages Contributes to Obesity-Associated Adipose Tissue Inflammation
- (2014) Shinya U. Amano et al. Cell Metabolism
- Inflammatory Cytokine Production by Human Neutrophils Involves C/EBP Transcription Factors
- (2014) A. Cloutier et al. JOURNAL OF IMMUNOLOGY
- Loss of CCR5 results in glucose intolerance in diet-induced obese mice
- (2013) Arion Kennedy et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Ciliary subcellular localization of TGR5 determines the cholangiocyte functional response to bile acid signaling
- (2013) Anatoliy I. Masyuk et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- The Origins and Drivers of Insulin Resistance
- (2013) Andrew M.F. Johnson et al. CELL
- The receptor TGR5 protects the liver from bile acid overload during liver regeneration in mice
- (2013) Noémie Péan et al. HEPATOLOGY
- TGR5 signalling inhibits the production of pro-inflammatory cytokines byin vitrodifferentiated inflammatory and intestinal macrophages in Crohn's disease
- (2013) Kazuaki Yoneno et al. IMMUNOLOGY
- The TGR5 receptor mediates bile acid–induced itch and analgesia
- (2013) Farzad Alemi et al. JOURNAL OF CLINICAL INVESTIGATION
- The Complement Anaphylatoxin C5a Receptor Contributes to Obese Adipose Tissue Inflammation and Insulin Resistance
- (2013) J. Phieler et al. JOURNAL OF IMMUNOLOGY
- Bile acids PKA-dependently induce a switch of the IL-10/IL-12 ratio and reduce proinflammatory capability of human macrophages
- (2013) Katrin Haselow et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Macrophage biology in development, homeostasis and disease
- (2013) Thomas A. Wynn et al. NATURE
- The bile acid receptor, TGR5, regulates basal and cholinergic-induced secretory responses in rat colon
- (2013) J. B. J. Ward et al. NEUROGASTROENTEROLOGY AND MOTILITY
- Gene silencing in adipose tissue macrophages regulates whole-body metabolism in obese mice
- (2013) M. Aouadi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Pleiotropic Actions of Insulin Resistance and Inflammation in Metabolic Homeostasis
- (2013) J. I. Odegaard et al. SCIENCE
- The role of innate immune cells in obese adipose tissue inflammation and development of insulin resistance
- (2013) Triantafyllos Chavakis et al. THROMBOSIS AND HAEMOSTASIS
- Colesevelam suppresses hepatic glycogenolysis by TGR5-mediated induction of GLP-1 action in DIO mice
- (2012) Matthew J. Potthoff et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- Activation of transmembrane bile acid receptor TGR5 stimulates insulin secretion in pancreatic β cells
- (2012) Divya P. Kumar et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Inflammation and Lipid Signaling in the Etiology of Insulin Resistance
- (2012) Christopher K. Glass et al. Cell Metabolism
- C5L2 and C5aR interaction in adipocytes and macrophages: Insights into adipoimmunology
- (2012) Pegah Poursharifi et al. CELLULAR SIGNALLING
- Neuropeptide Y1 Receptor in Immune Cells Regulates Inflammation and Insulin Resistance Associated With Diet-Induced Obesity
- (2012) L. Macia et al. DIABETES
- Monocyte chemoattractant protein-1 (MCP-1) deficiency enhances alternatively activated M2 macrophages and ameliorates insulin resistance and fatty liver in lipoatrophic diabetic A-ZIP transgenic mice
- (2012) Y. Nio et al. DIABETOLOGIA
- C5aR and C3aR antagonists each inhibit diet-induced obesity, metabolic dysfunction, and adipocyte and macrophage signaling
- (2012) Junxian Lim et al. FASEB JOURNAL
- The Receptor TGR5 Mediates the Prokinetic Actions of Intestinal Bile Acids and Is Required for Normal Defecation in Mice
- (2012) Farzad Alemi et al. GASTROENTEROLOGY
- Transcriptional Repression ofATF4Gene by CCAAT/Enhancer-binding Protein β (C/EBPβ) Differentially Regulates Integrated Stress Response
- (2012) Souvik Dey et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- CCAAT/Enhancer-binding Protein β (C/EBPβ) Expression Regulates Dietary-induced Inflammation in Macrophages and Adipose Tissue in Mice
- (2012) Shaikh M. Rahman et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- G protein–coupled receptor 21 deletion improves insulin sensitivity in diet-induced obese mice
- (2012) Olivia Osborn et al. JOURNAL OF CLINICAL INVESTIGATION
- The cellular and signaling networks linking the immune system and metabolism in disease
- (2012) Olivia Osborn et al. NATURE MEDICINE
- JNK Expression by Macrophages Promotes Obesity-Induced Insulin Resistance and Inflammation
- (2012) M. S. Han et al. SCIENCE
- TGR5 potentiates GLP-1 secretion in response to anionic exchange resins
- (2012) Taoufiq Harach et al. Scientific Reports
- Inflammatory Mechanisms in Obesity
- (2011) Margaret F. Gregor et al. Annual Review of Immunology
- TGR5 Activation Inhibits Atherosclerosis by Reducing Macrophage Inflammation and Lipid Loading
- (2011) Thijs W.H. Pols et al. Cell Metabolism
- The Bile Acid Membrane Receptor TGR5: A Valuable Metabolic Target
- (2011) Thijs W.H. Pols et al. DIGESTIVE DISEASES
- The G-Protein-coupled bile acid receptor, Gpbar1 (TGR5), negatively regulates hepatic inflammatory response through antagonizing nuclear factor kappa light-chain enhancer of activated B cells (NF-κB) in mice
- (2011) Yan-Dong Wang et al. HEPATOLOGY
- Inflammatory links between obesity and metabolic disease
- (2011) Carey N. Lumeng et al. JOURNAL OF CLINICAL INVESTIGATION
- Rapamycin inhibits osteoclast formation in giant cell tumor of bone through the C/EBPβ - MafB axis
- (2011) Jeske J. Smink et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- Type 2 diabetes across generations: from pathophysiology to prevention and management
- (2011) Christopher J Nolan et al. LANCET
- C/EBP , C/EBP Oncoproteins, or C/EBP Preferentially Bind NF- B p50 Compared with p65, Focusing Therapeutic Targeting on the C/EBP:p50 Interaction
- (2011) J. E. Dooher et al. MOLECULAR CANCER RESEARCH
- The G Protein-Coupled Bile Acid Receptor, TGR5, Stimulates Gallbladder Filling
- (2011) Tingting Li et al. MOLECULAR ENDOCRINOLOGY
- The Bile Acid Receptor GPBAR-1 (TGR5) Modulates Integrity of Intestinal Barrier and Immune Response to Experimental Colitis
- (2011) Sabrina Cipriani et al. PLoS One
- Macrophages, Inflammation, and Insulin Resistance
- (2010) Jerrold M. Olefsky et al. Annual Review of Physiology
- HER2 Silences Tumor Suppression in Breast Cancer Cells by Switching Expression of C/EBP Isoforms
- (2010) A. Arnal-Estape et al. CANCER RESEARCH
- GPR120 Is an Omega-3 Fatty Acid Receptor Mediating Potent Anti-inflammatory and Insulin-Sensitizing Effects
- (2010) Da Young Oh et al. CELL
- C/EBP uORF mice--a genetic model for uORF-mediated translational control in mammals
- (2010) K. Wethmar et al. GENES & DEVELOPMENT
- CCAAT/Enhancer-binding Protein β and NF-κB Mediate High Level Expression of Chemokine GenesCCL3andCCL4by Human Chondrocytes in Response to IL-1β
- (2010) Zhiqi Zhang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The bile acid membrane receptor TGR5 as an emerging target in metabolism and inflammation
- (2010) Thijs W.H. Pols et al. JOURNAL OF HEPATOLOGY
- Hydrophobic bile salts inhibit gallbladder smooth muscle function via stimulation of GPBAR1 receptors and activation of KATPchannels
- (2010) Brigitte Lavoie et al. JOURNAL OF PHYSIOLOGY-LONDON
- Expression and function of the bile acid receptor GpBAR1 (TGR5) in the murine enteric nervous system
- (2010) D. P. Poole et al. NEUROGASTROENTEROLOGY AND MOTILITY
- Mutational Characterization of the Bile Acid Receptor TGR5 in Primary Sclerosing Cholangitis
- (2010) Johannes R. Hov et al. PLoS One
- TGR5-Mediated Bile Acid Sensing Controls Glucose Homeostasis
- (2009) Charles Thomas et al. Cell Metabolism
- Transcription factor C/EBPβ isoform ratio regulates osteoclastogenesis through MafB
- (2009) Jeske J Smink et al. EMBO JOURNAL
- The membrane-bound bile acid receptor TGR5 is localized in the epithelium of human gallbladders
- (2009) Verena Keitel et al. HEPATOLOGY
- Discovery of 6α-Ethyl-23(S)-methylcholic Acid (S-EMCA, INT-777) as a Potent and Selective Agonist for the TGR5 Receptor, a Novel Target for Diabesity
- (2009) Roberto Pellicciari et al. JOURNAL OF MEDICINAL CHEMISTRY
- Inhibition of CCR2 Ameliorates Insulin Resistance and Hepatic Steatosis in db/db Mice
- (2008) Yukinori Tamura et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Novel Potent and Selective Bile Acid Derivatives as TGR5 Agonists: Biological Screening, Structure−Activity Relationships, and Molecular Modeling Studies
- (2008) Hiroyuki Sato et al. JOURNAL OF MEDICINAL CHEMISTRY
- Metabolic profiling of the human response to a glucose challenge reveals distinct axes of insulin sensitivity
- (2008) Oded Shaham et al. Molecular Systems Biology
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