C5aR and C3aR antagonists each inhibit diet-induced obesity, metabolic dysfunction, and adipocyte and macrophage signaling

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Weight loss and lipolysis promote a dynamic immune response in murine adipose tissue

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Complement: a key system for immune surveillance and homeostasis

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Inflammatory lipid mediators in adipocyte function and obesity

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Profiling Gene Expression Induced by Protease-Activated Receptor 2 (PAR2) Activation in Human Kidney Cells

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Metabolic Syndrome and Altered Gut Microbiota in Mice Lacking Toll-Like Receptor 5

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Complement component 3 polymorphisms interact with polyunsaturated fatty acids to modulate risk of metabolic syndrome

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The C3a Anaphylatoxin Receptor Is a Key Mediator of Insulin Resistance and Functions by Modulating Adipose Tissue Macrophage Infiltration and Activation

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Validation of candidate causal genes for obesity that affect shared metabolic pathways and networks

(2009) Xia Yang et al.   NATURE GENETICS

AdPLA ablation increases lipolysis and prevents obesity induced by high-fat feeding or leptin deficiency

(2009) Kathy Jaworski et al.   NATURE MEDICINE

Genetic deficiency and pharmacological stabilization of mast cells reduce diet-induced obesity and diabetes in mice

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CD8+ effector T cells contribute to macrophage recruitment and adipose tissue inflammation in obesity

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