Estrogen Receptor α Mediates Proliferation of Osteoblastic Cells Stimulated by Estrogen and Mechanical Strain, but Their Acute Down-regulation of the Wnt AntagonistSostIs Mediated by Estrogen Receptor β

Mechanotransduction in bone tissue: The A214V and G171V mutations in Lrp5 enhance load-induced osteogenesis in a surface-selective manner

(2012) Paul J. Niziolek et al.   BONE

Estrogen receptor beta binds Sp1 and recruits a corepressor complex to the estrogen receptor alpha gene promoter

(2012) V. Bartella et al.   BREAST CANCER RESEARCH AND TREATMENT

Estrogen Receptors α and β Have Different Gender-Dependent Effects on the Adaptive Responses to Load Bearing in Cancellous and Cortical Bone

(2012) L. K. Saxon et al.   ENDOCRINOLOGY

Biomechanical stimulation of osteoblast gene expression requires phosphorylation of the RUNX2 transcription factor

(2012) Yan Li et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Estrogen receptor-α is required for the osteogenic response to mechanical loading in a ligand-independent manner involving its activation function 1 but not 2

(2012) Sara H Windahl et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Estrogen receptor-α signaling in osteoblast progenitors stimulates cortical bone accrual

(2012) Maria Almeida et al.   JOURNAL OF CLINICAL INVESTIGATION

Differential Effects of Short Term Feeding of a Soy Protein Isolate Diet and Estrogen Treatment on Bone in the Pre-Pubertal Rat

(2012) Jian Zhang et al.   PLoS One

Estrogen receptor β stimulates Egr-1 transcription via MEK1/Erk/Elk-1 cascade in C6 glioma cells

(2011) Ji-Ha Kim et al.   BMB Reports

Sclerostin expression is induced by BMPs in human Saos-2 osteosarcoma cells but not via direct effects on the sclerostin gene promoter or ECR5 element

(2011) Longchuan Yu et al.   BONE

Analysis of multiple bone responses to graded strains above functional levels, and to disuse, in mice in vivo show that the human Lrp5 G171V High Bone Mass mutation increases the osteogenic response to loading but that lack of Lrp5 activity reduces it

(2011) Leanne K. Saxon et al.   BONE

Sost downregulation and local Wnt signaling are required for the osteogenic response to mechanical loading

(2011) Xiaolin Tu et al.   BONE

Tamoxifen increases nuclear respiratory factor 1 transcription by activating estrogen receptor β and AP-1 recruitment to adjacent promoter binding sites

(2011) Margarita M. Ivanova et al.   FASEB JOURNAL

Sostdown-regulation by mechanical strain in human osteoblastic cells involves PGE2 signaling via EP4

(2011) Gabriel L. Galea et al.   FEBS LETTERS

β-Catenin independent cross-control between the estradiol and Wnt pathways in osteoblasts

(2011) Thomas L. McCarthy et al.   GENE

Cell line IDG-SW3 replicates osteoblast-to-late-osteocyte differentiation in vitro and accelerates bone formation in vivo

(2011) Stacey M Woo et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Sex specific response of cultured human bone cells to ERα and ERβ specific agonists by modulation of cell proliferation and creatine kinase specific activity

(2011) Dalia Somjen et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Soy isoflavones for osteoporosis: An evidence-based approach

(2011) Kyoko Taku et al.   MATURITAS

Differential responsiveness to 17β-estradiol of mesenchymal stem cells from postmenopausal women between osteoporosis and osteoarthritis

(2011) W.-J. Jin et al.   OSTEOPOROSIS INTERNATIONAL

Decreased serum sclerostin levels in patients with primary hyperparathyroidism: a cross-sectional and a longitudinal study

(2011) M.-S. M. Ardawi et al.   OSTEOPOROSIS INTERNATIONAL

Mechanical loading-related changes in osteocyte sclerostin expression in mice are more closely associated with the subsequent osteogenic response than the peak strains engendered

(2011) A. Moustafa et al.   OSTEOPOROSIS INTERNATIONAL

Remodeling of Actin Cytoskeleton in Mouse Periosteal Cells under Mechanical Loading Induces Periosteal Cell Proliferation during Bone Formation

(2011) Daisuke Sakai et al.   PLoS One

Roles of transactivating functions 1 and 2 of estrogen receptor-  in bone

(2011) A. E. Borjesson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanical Loading-Related Bone Gain Is Enhanced by Tamoxifen but Unaffected by Fulvestrant in Female Mice

(2010) Toshihiro Sugiyama et al.   ENDOCRINOLOGY

Estrogen Signaling via Estrogen Receptor β

(2010) Chunyan Zhao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Distinct Modes of Inhibition by Sclerostin on Bone Morphogenetic Protein and Wnt Signaling Pathways

(2010) Carola Krause et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Direct transformation from quiescence to bone formation in the adult periosteum following a single brief period of bone loading

(2010) Matthew J. Pead et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Estrogen receptor α36 mediates a bone-sparing effect of 17β-estrodiol in postmenopausal women

(2010) Hui Xie et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Gene expression patterns in bone following mechanical loading

(2010) Sara M Mantila Roosa et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Single-dose, placebo-controlled, randomized study of AMG 785, a sclerostin monoclonal antibody

(2010) Desmond Padhi et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Regulation of circulating sclerostin levels by sex steroids in women and in men

(2010) Ulrike IL Mödder et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Relation of age, gender, and bone mass to circulating sclerostin levels in women and men

(2010) Ulrike I Mödder et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Reprogramming the pluripotent cell cycle: Restoration of an abbreviated G1 phase in human induced pluripotent stem (iPS) cells

(2010) Prachi N. Ghule et al.   JOURNAL OF CELLULAR PHYSIOLOGY

ER-α36, a Novel Variant of ER-α, Mediates Estrogen-Stimulated Proliferation of Endometrial Carcinoma Cells via the PKCδ/ERK Pathway

(2010) Jing-Shan Tong et al.   PLoS One

The Effects of 17-β Estradiol on Enhancing Proliferation of Human Bone Marrow Mesenchymal Stromal Cells In Vitro

(2010) Liu Hong et al.   STEM CELLS AND DEVELOPMENT

Loading-related regulation of gene expression in bone in the contexts of estrogen deficiency, lack of estrogen receptor α and disuse

(2009) Gul Zaman et al.   BONE

Osteocyte apoptosis and control of bone resorption following ovariectomy in mice

(2009) K.B. Emerton et al.   BONE

Transcriptional activation of insulin-like growth factor binding protein 6 by 17β-estradiol in SaOS-2 cells

(2009) Yu-yan Zhao et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

Mechanical Loading Regulates NFATc1 and β-Catenin Signaling through a GSK3β Control Node

(2009) Buer Sen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mechano-transduction in Osteoblastic Cells Involves Strain-regulated Estrogen Receptor α-mediated Control of Insulin-like Growth Factor (IGF) I Receptor Sensitivity to Ambient IGF, Leading to Phosphatidylinositol 3-Kinase/AKT-dependent Wnt/LRP5 Receptor-independent Activation of β-Catenin Signaling

(2009) Andrew Sunters et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Androgen receptor disruption increases the osteogenic response to mechanical loading in male mice

(2009) Filip Callewaert et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Human embryonic stem cells are pre-mitotically committed to self-renewal and acquire a lengthened G1 phase upon lineage programming

(2009) Klaus A. Becker et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Steroid regulation of proliferation and osteogenic differentiation of bone marrow stromal cells: A gender difference

(2009) Liu Hong et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Estrogen regulation of apoptosis in osteoblasts

(2009) Peter G. Bradford et al.   PHYSIOLOGY & BEHAVIOR

Mechanical loading enhances the anabolic effects of intermittent parathyroid hormone (1–34) on trabecular and cortical bone in mice

(2008) Toshihiro Sugiyama et al.   BONE

Estrogen protects bone by inducing Fas ligand in osteoblasts to regulate osteoclast survival

(2008) Susan A Krum et al.   EMBO JOURNAL

Modulation of Runx2 Activity by Estrogen Receptor-α: Implications for Osteoporosis and Breast Cancer

(2008) Omar Khalid et al.   ENDOCRINOLOGY

Differentiation and Proliferation of Periosteal Osteoblast Progenitors Are Differentially Regulated by Estrogens and Intermittent Parathyroid Hormone Administration

(2008) Mami Ogita et al.   ENDOCRINOLOGY

Mechanical Strain Inhibits Adipogenesis in Mesenchymal Stem Cells by Stimulating a Durable β-Catenin Signal

(2008) Buer Sen et al.   ENDOCRINOLOGY

β-Catenin Levels Influence Rapid Mechanical Responses in Osteoblasts

(2008) Natasha Case et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Osteocyte Apoptosis Controls Activation of Intracortical Resorption in Response to Bone Fatigue

(2008) Luis Cardoso et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Tamoxifen Use and Osteoporotic Fracture Risk: A Population-Based Analysis

(2008) Andrew L. Cooke et al.   JOURNAL OF CLINICAL ONCOLOGY

Estrogen and the selective estrogen receptor modulator (SERM) protection against cell death in estrogen receptor alpha and beta expressing U2OS cells

(2008) Anu Kallio et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Estrogen Receptor β Isoform-Specific Induction of Transforming Growth Factor β-Inducible Early Gene-1 in Human Osteoblast Cells: An Essential Role for the Activation Function 1 Domain

(2008) John R. Hawse et al.   MOLECULAR ENDOCRINOLOGY