Micropatterned coculture of primary human hepatocytes and supportive cells for the study of hepatotropic pathogens
出版年份 2015 全文链接
标题
Micropatterned coculture of primary human hepatocytes and supportive cells for the study of hepatotropic pathogens
作者
关键词
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出版物
Nature Protocols
Volume 10, Issue 12, Pages 2027-2053
出版商
Springer Nature
发表日期
2015-11-20
DOI
10.1038/nprot.2015.128
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Enhancing the functional maturity of induced pluripotent stem cell-derived human hepatocytes by controlled presentation of cell-cell interactionsin vitro
- (2015) Dustin R. Berger et al. HEPATOLOGY
- Hormone and Drug-Mediated Modulation of Glucose Metabolism in a Microscale Model of the Human Liver
- (2015) Matthew D. Davidson et al. TISSUE ENGINEERING PART C-METHODS
- A Micropatterned Hepatocyte Coculture Model for Assessment of Liver Toxicity Using High-Content Imaging Analysis
- (2014) O. Joseph Trask et al. ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES
- Pluripotent stem cell-derived hepatocyte-like cells
- (2014) R.E. Schwartz et al. BIOTECHNOLOGY ADVANCES
- Of men in mice: the success and promise of humanized mouse models for human malaria parasite infections
- (2014) Alexis Kaushansky et al. CELLULAR MICROBIOLOGY
- Microfluidic organs-on-chips
- (2014) Sangeeta N Bhatia et al. NATURE BIOTECHNOLOGY
- Persistence and activation of malaria hypnozoites in long-term primary hepatocyte cultures
- (2014) Laurent Dembélé et al. NATURE MEDICINE
- Modeling host interactions with hepatitis B virus using primary and induced pluripotent stem cell-derived hepatocellular systems
- (2014) A. Shlomai et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME
- (2013) Patricio Godoy et al. ARCHIVES OF TOXICOLOGY
- A Microscale Human Liver Platform that Supports the Hepatic Stages of Plasmodium falciparum and vivax
- (2013) Sandra March et al. Cell Host & Microbe
- Hypoxia promotes liver-stage malaria infection in primary human hepatocytes in vitro
- (2013) S. Ng et al. Disease Models & Mechanisms
- Long-Term Stability of Primary Rat Hepatocytes in Micropatterned Cocultures
- (2013) Okechukwu Ukairo et al. JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY
- On the History of Hepatitis C Virus Cell Culture Systems
- (2013) Volker Lohmann et al. JOURNAL OF MEDICINAL CHEMISTRY
- Identification of small molecules for human hepatocyte expansion and iPS differentiation
- (2013) Jing Shan et al. Nature Chemical Biology
- Comparison of Human Hepatoma HepaRG Cells with Human and Rat Hepatocytes in Uptake Transport Assays in Order to Predict a Risk of Drug Induced Hepatotoxicity
- (2013) Monika Szabo et al. PLoS One
- Polarized expression of drug transporters in differentiated human hepatoma HepaRG cells
- (2013) Marc Le Vee et al. TOXICOLOGY IN VITRO
- Characterization of primary human hepatocytes, HepG2 cells, and HepaRG cells at the mRNA level and CYP activity in response to inducers and their predictivity for the detection of human hepatotoxins
- (2012) H. H. J. Gerets et al. CELL BIOLOGY AND TOXICOLOGY
- Organotypic liver culture models: Meeting current challenges in toxicity testing
- (2012) Edward L. LeCluyse et al. CRITICAL REVIEWS IN TOXICOLOGY
- The HepaRG cell line: a uniquein vitrotool for understanding drug metabolism and toxicology in human
- (2012) Tommy B Andersson et al. Expert Opinion on Drug Metabolism & Toxicology
- Efficient replication of primary or culture hepatitis C virus isolates in human liver slices: A relevantex vivomodel of liver infection
- (2012) Sylvie Lagaye et al. HEPATOLOGY
- Chronic hepatitis C virus (HCV) disease burden and cost in the United States
- (2012) Homie Razavi et al. HEPATOLOGY
- Complete Plasmodium falciparum liver-stage development in liver-chimeric mice
- (2012) Ashley M. Vaughan et al. JOURNAL OF CLINICAL INVESTIGATION
- Use of Micropatterned Cocultures to Detect Compounds That Cause Drug-Induced Liver Injury in Humans
- (2012) Salman R. Khetani et al. TOXICOLOGICAL SCIENCES
- Hydrogel embedding of precision-cut liver slices in a microfluidic device improves drug metabolic activity
- (2011) Paul M. van Midwoud et al. BIOTECHNOLOGY AND BIOENGINEERING
- Superinfection in malaria: Plasmodium shows its iron will
- (2011) Sílvia Portugal et al. EMBO REPORTS
- Towards an In Vitro Model of Plasmodium Hypnozoites Suitable for Drug Discovery
- (2011) Laurent Dembele et al. PLoS One
- Live Attenuated Malaria Vaccine Designed to Protect Through Hepatic CD8+ T Cell Immunity
- (2011) J. E. Epstein et al. SCIENCE
- A Research Agenda to Underpin Malaria Eradication
- (2011) Pedro L. Alonso et al. PLOS MEDICINE
- Assessment of a Micropatterned Hepatocyte Coculture System to Generate Major Human Excretory and Circulating Drug Metabolites
- (2010) W. W. Wang et al. DRUG METABOLISM AND DISPOSITION
- Primary hepatocyte culture supports hepatitis C virus replication: A model for infection-associated hepatocarcinogenesis
- (2010) Krishna Banaudha et al. HEPATOLOGY
- Development of a metabolically active, non-replicating sporozoite vaccine to preventPlasmodium falciparummalaria
- (2010) Stephen L. Hoffman et al. Human vaccines & immunotherapeutics
- Apoptosis of Hepatitis B Virus-Infected Hepatocytes Prevents Release of Infectious Virus
- (2010) S. Arzberger et al. JOURNAL OF VIROLOGY
- Real-time imaging of hepatitis C virus infection using a fluorescent cell-based reporter system
- (2010) Christopher T Jones et al. NATURE BIOTECHNOLOGY
- Soft lithography for micro- and nanoscale patterning
- (2010) Dong Qin et al. Nature Protocols
- An Implantable Vascularized Protein Gel Construct That Supports Human Fetal Hepatoblast Survival and Infection by Hepatitis C Virus in Mice
- (2010) Martha J. Harding et al. PLoS One
- Establishment of an In Vitro Assay for Assessing the Effects of Drugs on the Liver Stages of Plasmodium vivax Malaria
- (2010) Rana Chattopadhyay et al. PLoS One
- Persistent hepatitis C virus infection in microscale primary human hepatocyte cultures
- (2010) A. Ploss et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Targeting the hypnozoite reservoir of Plasmodium vivax: the hidden obstacle to malaria elimination
- (2010) Timothy N.C. Wells et al. TRENDS IN PARASITOLOGY
- HepaRG human hepatic cell line utility as a surrogate for primary human hepatocytes in drug metabolism assessment in vitro
- (2010) Marc Lübberstedt et al. JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS
- Host cell transcriptional profiling during malaria liver stage infection reveals a coordinated and sequential set of biological events
- (2009) Sónia S Albuquerque et al. BMC GENOMICS
- Which Human Metabolites Have We MIST? Retrospective Analysis, Practical Aspects, and Perspectives For Metabolite Identification and Quantification in Pharmaceutical Development
- (2009) Laurent Leclercq et al. CHEMICAL RESEARCH IN TOXICOLOGY
- Microenvironmental regulation of the sinusoidal endothelial cell phenotype in vitro
- (2009) Sandra March et al. HEPATOLOGY
- Highly efficient generation of human hepatocyte-like cells from induced pluripotent stem cells
- (2009) Karim Si-Tayeb et al. HEPATOLOGY
- The global burden of hepatitis C
- (2009) Daniel Lavanchy LIVER INTERNATIONAL
- New medicines to improve control and contribute to the eradication of malaria
- (2009) Timothy N. C. Wells et al. NATURE REVIEWS DRUG DISCOVERY
- Modulation of hepatocyte phenotype in vitro via chemomechanical tuning of polyelectrolyte multilayers
- (2008) Alice A. Chen et al. BIOMATERIALS
- Scavenger Receptor BI Boosts Hepatocyte Permissiveness to Plasmodium Infection
- (2008) Samir Yalaoui et al. Cell Host & Microbe
- Evolving concepts in liver tissue modeling and implications forin vitrotoxicology
- (2008) André Guillouzo et al. Expert Opinion on Drug Metabolism & Toxicology
- T-cadherin modulates hepatocyte functions in vitro
- (2008) Salman R. Khetani et al. FASEB JOURNAL
- Cell culture-produced hepatitis C virus does not infect peripheral blood mononuclear cells
- (2008) Svetlana Marukian et al. HEPATOLOGY
- Direct Infection and Replication of Naturally Occurring Hepatitis C Virus Genotypes 1, 2, 3 and 4 in Normal Human Hepatocyte Cultures
- (2008) Martina Buck PLoS One
- Gene Disruption of Plasmodium falciparum p52 Results in Attenuation of Malaria Liver Stage Development in Cultured Primary Human Hepatocytes
- (2008) Ben C. L. van Schaijk et al. PLoS One
- Cellular Imaging Predictions of Clinical Drug-Induced Liver Injury
- (2008) Jinghai J. Xu et al. TOXICOLOGICAL SCIENCES
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