It takes two to tango: IκBs, the multifunctional partners of NF-κB

Regulation of NF-κB by ubiquitination and degradation of the IκBs

(2012) Naama Kanarek et al.   IMMUNOLOGICAL REVIEWS

NF-κB regulation: lessons from structures

(2012) Gourisankar Ghosh et al.   IMMUNOLOGICAL REVIEWS

NF-κB: where did it come from and why?

(2012) Thomas D. Gilmore et al.   IMMUNOLOGICAL REVIEWS

Pathogenetic importance and therapeutic implications of NF-κB in lymphoid malignancies

(2012) Kian-Huat Lim et al.   IMMUNOLOGICAL REVIEWS

Lessons from mathematically modeling the NF-κB pathway

(2012) Soumen Basak et al.   IMMUNOLOGICAL REVIEWS

Regulation of NF-κB by deubiquitinases

(2012) Edward W. Harhaj et al.   IMMUNOLOGICAL REVIEWS

The noncanonical NF-κB pathway

(2012) Shao-Cong Sun   IMMUNOLOGICAL REVIEWS

NF-κB and the link between inflammation and cancer

(2012) Joseph A. DiDonato et al.   IMMUNOLOGICAL REVIEWS

I B  augments IL-12- and IL-18-mediated IFN-  production in human NK cells

(2011) Y. Kannan et al.   BLOOD

IκBζ expression is regulated by miR-124a

(2011) Charlotte Lindenblatt et al.   CELL CYCLE

Endogenous Muscle Atrophy F-Box Mediates Pressure Overload–Induced Cardiac Hypertrophy Through Regulation of Nuclear Factor-κB

(2011) Soichiro Usui et al.   CIRCULATION RESEARCH

Nuclear Export of the NF-κB Inhibitor IκBα Is Required for Proper B Cell and Secondary Lymphoid Tissue Formation

(2011) Shelly M. Wuerzberger-Davis et al.   IMMUNITY

The I B Family Member Bcl-3 Coordinates the Pulmonary Defense against Klebsiella pneumoniae Infection

(2011) F. Pene et al.   JOURNAL OF IMMUNOLOGY

Inflammation meets cancer, with NF-κB as the matchmaker

(2011) Yinon Ben-Neriah et al.   NATURE IMMUNOLOGY

Identification of Genes that Elicit Disuse Muscle Atrophy via the Transcription Factors p50 and Bcl-3

(2011) Chia-Ling Wu et al.   PLoS One

Visualization of the nanospring dynamics of the I B  ankyrin repeat domain in real time

(2011) J. A. Lamboy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Detection of a ternary complex of NF- B and I B  with DNA provides insights into how I B  removes NF- B from transcription sites

(2011) S.-C. Sue et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular Mechanisms of System Control of NF-κB Signaling by IκBα

(2010) Diego U. Ferreiro et al.   BIOCHEMISTRY

Structural studies of NF-κB signaling

(2010) Chao Zheng et al.   CELL RESEARCH

MiR-125b targets BCL3 and suppresses ovarian cancer proliferation

(2010) Yi Guan et al.   INTERNATIONAL JOURNAL OF CANCER

Classical NF-κB Activation Negatively Regulates Noncanonical NF-κB-dependent CXCL12 Expression

(2010) Lisa A. Madge et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Bcl3 prevents acute inflammatory lung injury in mice by restraining emergency granulopoiesis

(2010) Daniel Kreisel et al.   JOURNAL OF CLINICAL INVESTIGATION

IκBβ is an essential co-activator for LPS-induced IL-1β transcription in vivo

(2010) Melanie Scheibel et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Characterization of the Core Elements of the NF- B Signaling Pathway of the Sea Anemone Nematostella vectensis

(2010) F. S. Wolenski et al.   MOLECULAR AND CELLULAR BIOLOGY

The Repressing Function of the Oncoprotein BCL-3 Requires CtBP, while Its Polyubiquitination and Degradation Involve the E3 Ligase TBLR1

(2010) A. Keutgens et al.   MOLECULAR AND CELLULAR BIOLOGY

IκBβ acts to inhibit and activate gene expression during the inflammatory response

(2010) Ping Rao et al.   NATURE

IκBζ regulates TH17 development by cooperating with ROR nuclear receptors

(2010) Kazuo Okamoto et al.   NATURE

Regulation of NF-κB inhibitor IκBα and viral replication by a KSHV microRNA

(2010) Xiufen Lei et al.   NATURE CELL BIOLOGY

A small-molecule inhibitor shows that pirin regulates migration of melanoma cells

(2010) Isao Miyazaki et al.   Nature Chemical Biology

NF-κB addiction and its role in cancer: ‘one size does not fit all’

(2010) M M Chaturvedi et al.   ONCOGENE

IκBζ is essential for natural killer cell activation in response to IL-12 and IL-18

(2010) Tohru Miyake et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

I B , a nuclear I B protein, positively regulates the NF- B-mediated expression of proinflammatory cytokines

(2010) S. Yamauchi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Variation in Transcription Factor Binding Among Humans

(2010) M. Kasowski et al.   SCIENCE

Regulation and Function of NF-κB Transcription Factors in the Immune System

(2009) Sivakumar Vallabhapurapu et al.   Annual Review of Immunology

Early evolution of metazoan transcription factors

(2009) Bernard M Degnan et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Down-regulation of CYLD expression by Snail promotes tumor progression in malignant melanoma

(2009) Ramin Massoumi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Bcl3 Interacts Cooperatively with Peroxisome Proliferator-Activated Receptor Gamma (PPAR ) Coactivator 1  To Coactivate Nuclear Receptors Estrogen-Related Receptor   and PPAR 

(2009) J. Yang et al.   MOLECULAR AND CELLULAR BIOLOGY

The Nfkb1 and Nfkb2 Proteins p105 and p100 Function as the Core of High-Molecular-Weight Heterogeneous Complexes

(2009) Olga V. Savinova et al.   MOLECULAR CELL

A Novel Role for IκBζ in the Regulation of IFNγ Production

(2009) Raquel M. Raices et al.   PLoS One

Kinetic enhancement of NF- B{middle dot}DNA dissociation by I B 

(2009) S. Bergqvist et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ubiquitination and Degradation of the Inhibitors of NF- B

(2009) N. Kanarek et al.   Cold Spring Harbor Perspectives in Biology

NF- B in the Immune Response of Drosophila

(2009) C. Hetru et al.   Cold Spring Harbor Perspectives in Biology

NF- B in the Nervous System

(2009) B. Kaltschmidt et al.   Cold Spring Harbor Perspectives in Biology

A Structural Guide to Proteins of the NF- B Signaling Module

(2009) T. Huxford et al.   Cold Spring Harbor Perspectives in Biology

Shared Principles in NF-κB Signaling

(2008) Matthew S. Hayden et al.   CELL

NF-κB dictates the degradation pathway of IκBα

(2008) Erika Mathes et al.   EMBO JOURNAL

Gene-specific Requirement of a Nuclear Protein, IκB-ζ, for Promoter Association of Inflammatory Transcription Regulators

(2008) Soh Yamazaki et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Transfer of Flexibility between Ankyrin Repeats in IκBα upon Formation of the NF-κB Complex

(2008) Shih-Che Sue et al.   JOURNAL OF MOLECULAR BIOLOGY

Proteolysis of NF-κB1 p105 is essential for T cell antigen receptor–induced proliferation

(2008) Srividya Sriskantharajah et al.   NATURE IMMUNOLOGY