标题
Targeting the lysosome in cancer
作者
关键词
-
出版物
Annals of the New York Academy of Sciences
Volume 1371, Issue 1, Pages 45-54
出版商
Wiley
发表日期
2015-11-25
DOI
10.1111/nyas.12953
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Synthesis and Evaluation of Cleistanthin A Derivatives as Potent Vacuolar H+-ATPase Inhibitors
- (2015) Yu Zhao et al. Chemical Biology & Drug Design
- Heme oxygenase-1 enhances autophagy in podocytes as a protective mechanism against high glucose-induced apoptosis
- (2015) Chenglong Dong et al. EXPERIMENTAL CELL RESEARCH
- Synthesis of Improved Lysomotropic Autophagy Inhibitors
- (2015) Tong Wang et al. JOURNAL OF MEDICINAL CHEMISTRY
- Selective autophagy: Lysophagy
- (2015) Junya Hasegawa et al. METHODS
- Receptor-mediated selective autophagy degrades the endoplasmic reticulum and the nucleus
- (2015) Keisuke Mochida et al. NATURE
- Transcriptional control of autophagy–lysosome function drives pancreatic cancer metabolism
- (2015) Rushika M. Perera et al. NATURE
- Lysosomal calcium signalling regulates autophagy through calcineurin and TFEB
- (2015) Diego L. Medina et al. NATURE CELL BIOLOGY
- Emerging strategies to effectively target autophagy in cancer
- (2015) V W Rebecca et al. ONCOGENE
- Discovery of Autophagy Inhibitors with Antiproliferative Activity in Lung and Pancreatic Cancer Cells
- (2015) Lars Ulrik Nordstrøm et al. ACS Medicinal Chemistry Letters
- V-ATPase: a master effector of E2F1-mediated lysosomal trafficking, mTORC1 activation and autophagy
- (2015) Nathalie Meo-Evoli et al. Oncotarget
- Abstract 4545: Anticancer effects and mechanism of VR23, a novel chloroquine derivative
- (2015) Hai-Yen Thi Vu et al. CANCER RESEARCH
- Targeting Cathepsin E in Pancreatic Cancer by a Small Molecule Allows In Vivo Detection
- (2015) Edmund J. Keliher et al. NEOPLASIA
- LC3-associated phagocytosis
- (2014) Susana Romao et al. Autophagy
- The current stage of cathepsin B inhibitors as potential anticancer agents
- (2014) Janko Kos et al. Future Medicinal Chemistry
- Bafilomycin A1 targets both autophagy and apoptosis pathways in pediatric B-cell acute lymphoblastic leukemia
- (2014) N. Yuan et al. HAEMATOLOGICA
- Lysosomal membrane permeabilization in cell death: Concepts and challenges
- (2014) Urška Repnik et al. MITOCHONDRION
- Efficacy of a Cathepsin K Inhibitor in a Preclinical Model for Prevention and Treatment of Breast Cancer Bone Metastasis
- (2014) L. T. Duong et al. MOLECULAR CANCER THERAPEUTICS
- Imaging the intracellular distribution of tyrosine kinase inhibitors in living cells with quantitative hyperspectral stimulated Raman scattering
- (2014) Dan Fu et al. Nature Chemistry
- The Complex Ultrastructure of the Endolysosomal System
- (2014) J. Klumperman et al. Cold Spring Harbor Perspectives in Biology
- Transformation-Associated Changes in Sphingolipid Metabolism Sensitize Cells to Lysosomal Cell Death Induced by Inhibitors of Acid Sphingomyelinase
- (2013) Nikolaj H.T. Petersen et al. CANCER CELL
- Chaperone-mediated autophagy: roles in disease and aging
- (2013) Ana Maria Cuervo et al. CELL RESEARCH
- The role of necroptosis, an alternative form of cell death, in cancer therapy
- (2013) Xinfang Yu et al. Expert Review of Anticancer Therapy
- Cathepsin S from both tumor and tumor-associated cells promote cancer growth and neovascularization
- (2013) Donna M. Small et al. INTERNATIONAL JOURNAL OF CANCER
- V-ATPase inhibition by archazolid leads to lysosomal dysfunction resulting in impaired cathepsin B activationin vivo
- (2013) Rebekka Kubisch et al. INTERNATIONAL JOURNAL OF CANCER
- Dipeptide mimic oligomer transporter mediates intracellular delivery of Cathepsin D inhibitors: A potential target for cancer therapy
- (2013) Marie Maynadier et al. JOURNAL OF CONTROLLED RELEASE
- Effects of novel human cathepsin S inhibitors on cell migration in human cancer cells
- (2013) Ju-Ying Tsai et al. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
- The Marine Natural Product Manzamine A Targets Vacuolar ATPases and Inhibits Autophagy in Pancreatic Cancer Cells
- (2013) Georgios Kallifatidis et al. Marine Drugs
- Killing from the inside
- (2013) Paul Saftig et al. NATURE
- The lysosome: from waste bag to potential therapeutic target
- (2013) Hanna Appelqvist et al. Journal of Molecular Cell Biology
- The Endolysosomal System in Cell Death and Survival
- (2013) U. Repnik et al. Cold Spring Harbor Perspectives in Biology
- HSP70 inhibition by 2-phenylethynesulfonamide induces lysosomal cathepsin D release and immunogenic cell death in primary effusion lymphoma
- (2013) M Granato et al. Cell Death & Disease
- Lys05
- (2012) Ravi K. Amaravadi et al. Autophagy
- Cathepsin B Inhibition Limits Bone Metastasis in Breast Cancer
- (2012) N. P. Withana et al. CANCER RESEARCH
- Lysosomal pathways to cell death and their therapeutic applications
- (2012) Maruša Hafner Česen et al. EXPERIMENTAL CELL RESEARCH
- Autophagy Suppresses RIP Kinase-Dependent Necrosis Enabling Survival to mTOR Inhibition
- (2012) Kevin Bray et al. PLoS One
- Autophagy inhibitor Lys05 has single-agent antitumor activity and reproduces the phenotype of a genetic autophagy deficiency
- (2012) Q. McAfee et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Lysosomes and lysosomal cathepsins in cell death
- (2011) Urška Repnik et al. BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS
- Hallmarks of Cancer: The Next Generation
- (2011) Douglas Hanahan et al. CELL
- Lysosomal Sequestration of Sunitinib: A Novel Mechanism of Drug Resistance
- (2011) K. J. Gotink et al. CLINICAL CANCER RESEARCH
- Principles and Current Strategies for Targeting Autophagy for Cancer Treatment
- (2011) R. K. Amaravadi et al. CLINICAL CANCER RESEARCH
- Characterization of the CLEAR network reveals an integrated control of cellular clearance pathways
- (2011) Michela Palmieri et al. HUMAN MOLECULAR GENETICS
- HSP70 Inhibition by the Small-Molecule 2-Phenylethynesulfonamide Impairs Protein Clearance Pathways in Tumor Cells
- (2011) J. I.-J. Leu et al. MOLECULAR CANCER RESEARCH
- TFEB Links Autophagy to Lysosomal Biogenesis
- (2011) C. Settembre et al. SCIENCE
- Lysosomal membrane proteins: life between acid and neutral conditions: Figure 1
- (2010) Paul Saftig et al. BIOCHEMICAL SOCIETY TRANSACTIONS
- The Acid Sphingomyelinase/Ceramide Pathway: Biomedical Significance and Mechanisms of Regulation
- (2010) Y.H. Zeidan et al. CURRENT MOLECULAR MEDICINE
- Molecular mechanisms of necroptosis: an ordered cellular explosion
- (2010) Peter Vandenabeele et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- The proteome of lysosomes
- (2010) Bernd A. Schröder et al. PROTEOMICS
- Cathepsin K inhibitors for osteoporosis and potential off-target effects
- (2009) Dieter Brömme et al. EXPERT OPINION ON INVESTIGATIONAL DRUGS
- Cathepsin L, target in cancer treatment?
- (2009) Jacqueline M. Lankelma et al. LIFE SCIENCES
- Major cell death pathways at a glance
- (2009) Linde Duprez et al. MICROBES AND INFECTION
- Lysosome biogenesis and lysosomal membrane proteins: trafficking meets function
- (2009) Paul Saftig et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Lysosomal involvement in cell death and cancer
- (2008) Thomas Kirkegaard et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Lysosomes in iron metabolism, ageing and apoptosis
- (2008) Tino Kurz et al. HISTOCHEMISTRY AND CELL BIOLOGY
- Acid Sphingomyelinase Overexpression Enhances the Antineoplastic Effects of Irradiation In Vitro and In Vivo
- (2008) Eric L Smith et al. MOLECULAR THERAPY
- Lysosomal membrane permeabilization in cell death
- (2008) P Boya et al. ONCOGENE
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