标题
The lysosome: from waste bag to potential therapeutic target
作者
关键词
-
出版物
Journal of Molecular Cell Biology
Volume 5, Issue 4, Pages 214-226
出版商
Oxford University Press (OUP)
发表日期
2013-08-05
DOI
10.1093/jmcb/mjt022
参考文献
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注意：仅列出部分参考文献，下载原文获取全部文献信息。- Breast cancer invasion is mediated by β-N-acetylglucosaminidase (β-NAG) and associated with a dysregulation in the secretory pathway of cancer cells
- (2016) K. T. Ramessur et al. BRITISH JOURNAL OF BIOMEDICAL SCIENCE
- Neurodegenerative lysosomal disorders: A continuum from development to late age
- (2014) Ralph A. Nixon et al. Autophagy
- The end of autophagic cell death?
- (2012) Shensi Shen et al. Autophagy
- The histone deacetylase inhibitor trichostatin A reduces lysosomal pH and enhances cisplatin-induced apoptosis
- (2012) I. Eriksson et al. EXPERIMENTAL CELL RESEARCH
- Treatment options for lysosomal storage disorders: developing insights
- (2012) Carin M van Gelder et al. EXPERT OPINION ON PHARMACOTHERAPY
- Proteolysis of cystatin C by cathepsin D in the breast cancer microenvironment
- (2012) Valérie Laurent-Matha et al. FASEB JOURNAL
- Impaired proteolysis underlies autophagic dysfunction in Niemann–Pick type C disease
- (2012) Matthew J. Elrick et al. HUMAN MOLECULAR GENETICS
- Inhibitors of vacuolar ATPase proton pumps inhibit human prostate cancer cell invasion and prostate-specific antigen expression and secretion
- (2012) Vera Michel et al. INTERNATIONAL JOURNAL OF CANCER
- Lysosomal calcium homeostasis defects, not proton pump defects, cause endo-lysosomal dysfunction in PSEN-deficient cells
- (2012) Katrijn Coen et al. JOURNAL OF CELL BIOLOGY
- Lysosomal storage disorders: The cellular impact of lysosomal dysfunction
- (2012) Frances M. Platt et al. JOURNAL OF CELL BIOLOGY
- M6P/IGF2R modulates the invasiveness of liver cells via its capacity to bind mannose 6-phosphate residues
- (2012) Verena Puxbaum et al. JOURNAL OF HEPATOLOGY
- Cancer-associated lysosomal changes: friends or foes?
- (2012) T Kallunki et al. ONCOGENE
- Inhibition of Glioma Cell Lysosome Exocytosis Inhibits Glioma Invasion
- (2012) Yu Liu et al. PLoS One
- Sensitivity to Lysosome-Dependent Cell Death Is Directly Regulated by Lysosomal Cholesterol Content
- (2012) Hanna Appelqvist et al. PLoS One
- Positive Lysosomal Modulation As a Unique Strategy to Treat Age-Related Protein Accumulation Diseases
- (2012) Ben A. Bahr et al. REJUVENATION RESEARCH
- The Transcription Factor TFEB Links mTORC1 Signaling to Transcriptional Control of Lysosome Homeostasis
- (2012) A. Roczniak-Ferguson et al. Science Signaling
- Membrane Trafficking in Osteoblasts and Osteoclasts: New Avenues for Understanding and Treating Skeletal Diseases
- (2012) Haibo Zhao TRAFFIC
- Mycobacteria and the Intraphagosomal Environment: Take It With a Pinch of Salt(s)!
- (2012) Thierry Soldati et al. TRAFFIC
- Chaperone-mediated autophagy: a unique way to enter the lysosome world
- (2012) Susmita Kaushik et al. TRENDS IN CELL BIOLOGY
- Amino acids and mTORC1: from lysosomes to disease
- (2012) Alejo Efeyan et al. TRENDS IN MOLECULAR MEDICINE
- Attenuation of the Lysosomal Death Pathway by Lysosomal Cholesterol Accumulation
- (2011) Hanna Appelqvist et al. AMERICAN JOURNAL OF PATHOLOGY
- Lysosomal Acidification Mechanisms
- (2011) Joseph A. Mindell Annual Review of Physiology
- Molecular mechanisms of endolysosomal Ca2+signalling in health and disease
- (2011) Anthony J. Morgan et al. BIOCHEMICAL JOURNAL
- Autophagy, mitochondria and oxidative stress: cross-talk and redox signalling
- (2011) Jisun Lee et al. BIOCHEMICAL JOURNAL
- The endosome–lysosome pathway and information generation in the immune system
- (2011) Colin Watts BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS
- Autophagy: Renovation of Cells and Tissues
- (2011) Noboru Mizushima et al. CELL
- Lysosomal Ca2+ homeostasis: Role in pathogenesis of lysosomal storage diseases
- (2011) Emyr Lloyd-Evans et al. CELL CALCIUM
- Microautophagy: lesser-known self-eating
- (2011) Wen-wen Li et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Transcriptional Activation of Lysosomal Exocytosis Promotes Cellular Clearance
- (2011) Diego L. Medina et al. DEVELOPMENTAL CELL
- Endosome maturation
- (2011) Jatta Huotari et al. EMBO JOURNAL
- Characterization of the CLEAR network reveals an integrated control of cellular clearance pathways
- (2011) Michela Palmieri et al. HUMAN MOLECULAR GENETICS
- Cysteine Protease Cathepsins in Atherosclerosis-Based Vascular Disease and Its Complications
- (2011) Xian Wu Cheng et al. HYPERTENSION
- Quantitative role of LAL, NPC2, and NPC1 in lysosomal cholesterol processing defined by genetic and pharmacological manipulations
- (2011) Charina M. Ramirez et al. JOURNAL OF LIPID RESEARCH
- Autophagy deregulation in neurodegenerative diseases - recent advances and future perspectives
- (2011) Zelda H. Cheung et al. JOURNAL OF NEUROCHEMISTRY
- Lysosomal positioning coordinates cellular nutrient responses
- (2011) Viktor I. Korolchuk et al. NATURE CELL BIOLOGY
- Stat3 controls lysosomal-mediated cell death in vivo
- (2011) Peter A. Kreuzaler et al. NATURE CELL BIOLOGY
- Control of autophagy as a therapy for neurodegenerative disease
- (2011) Harry Harris et al. Nature Reviews Neurology
- Autophagy failure in Alzheimer's disease—locating the primary defect
- (2011) Ralph A. Nixon et al. NEUROBIOLOGY OF DISEASE
- Protective Effects of Positive Lysosomal Modulation in Alzheimer's Disease Transgenic Mouse Models
- (2011) David Butler et al. PLoS One
- TFEB Links Autophagy to Lysosomal Biogenesis
- (2011) C. Settembre et al. SCIENCE
- Clarifying lysosomal storage diseases
- (2011) Mark L. Schultz et al. TRENDS IN NEUROSCIENCES
- MAGUKs, scaffolding proteins at cell junctions, are substrates of different proteases during apoptosis
- (2011) S Ivanova et al. Cell Death & Disease
- Regulation of apoptosis-associated lysosomal membrane permeabilization
- (2010) Ann-Charlotte Johansson et al. APOPTOSIS
- Lysosomal membrane proteins: life between acid and neutral conditions: Figure 1
- (2010) Paul Saftig et al. BIOCHEMICAL SOCIETY TRANSACTIONS
- Reversal of autophagy dysfunction in the TgCRND8 mouse model of Alzheimer's disease ameliorates amyloid pathologies and memory deficits
- (2010) Dun-Sheng Yang et al. BRAIN
- Combating apoptosis and multidrug resistant cancers by targeting lysosomes
- (2010) Line Groth-Pedersen et al. CANCER LETTERS
- Lysosomal Proteolysis and Autophagy Require Presenilin 1 and Are Disrupted by Alzheimer-Related PS1 Mutations
- (2010) Ju-Hyun Lee et al. CELL
- Nonesterified cholesterol content of lysosomes modulates susceptibility to oxidant-induced permeabilization
- (2010) John J. Reiners et al. FREE RADICAL BIOLOGY AND MEDICINE
- Molecular Interplay between Mammalian Target of Rapamycin (mTOR), Amyloid-β, and Tau
- (2010) Antonella Caccamo et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Exocytosis of acid sphingomyelinase by wounded cells promotes endocytosis and plasma membrane repair
- (2010) Christina Tam et al. JOURNAL OF CELL BIOLOGY
- Pathophysiology of neuropathic lysosomal storage disorders
- (2010) Cinzia Maria Bellettato et al. JOURNAL OF INHERITED METABOLIC DISEASE
- The birth prevalence of lysosomal storage disorders in the Czech Republic: comparison with data in different populations
- (2010) Helena Poupětová et al. JOURNAL OF INHERITED METABOLIC DISEASE
- Mitochondrial degradation in acetic acid-induced yeast apoptosis: the role of Pep4 and the ADP/ATP carrier
- (2010) Clara Pereira et al. MOLECULAR MICROBIOLOGY
- Plasma membrane signaling induced by ionizing radiation
- (2010) Isabelle Corre et al. MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH
- Hsp70 stabilizes lysosomes and reverts Niemann–Pick disease-associated lysosomal pathology
- (2010) Thomas Kirkegaard et al. NATURE
- NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals
- (2010) Peter Duewell et al. NATURE
- Niemann-Pick disease type C
- (2010) Marie T Vanier Orphanet Journal of Rare Diseases
- Lysosomal Storage Disease: Revealing Lysosomal Function and Physiology
- (2010) Emma J. Parkinson-Lawrence et al. PHYSIOLOGY
- Cyclodextrin Induces Calcium-Dependent Lysosomal Exocytosis
- (2010) Fannie W. Chen et al. PLoS One
- Autophagosome formation in mammalian cells
- (2010) Chloe Burman et al. Seminars in Immunopathology
- Structure of N-Terminal Domain of NPC1 Reveals Distinct Subdomains for Binding and Transfer of Cholesterol
- (2009) Hyock Joo Kwon et al. CELL
- Intrinsic differences in cisplatin sensitivity of head and neck cancer cell lines: Correlation to lysosomal pH
- (2009) Cathrine Nilsson et al. HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK
- Lysosomes as “Suicide Bags” in Cell Death: Myth or Reality?
- (2009) Boris Turk et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Mobilization of Lysosomal Calcium Regulates the Externalization of Phosphatidylserine during Apoptosis
- (2009) Banafsheh Mirnikjoo et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Inhibitors of the V0 subunit of the vacuolar H+-ATPase prevent segregation of lysosomal- and secretory-pathway proteins
- (2009) J. A. Sobota et al. JOURNAL OF CELL SCIENCE
- Redox-Dependent Translocation of p53 to Mitochondria or Nucleus in Human Melanocytes after UVA- and UVB-Induced Apoptosis
- (2009) Petra K. Wäster et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Disorders of Lysosome-Related Organelle Biogenesis: Clinical and Molecular Genetics
- (2008) Marjan Huizing et al. Annual Review of Genomics and Human Genetics
- Cathepsin L is significantly associated with apoptosis and plaque destabilization in human atherosclerosis
- (2008) Wei Li et al. ATHEROSCLEROSIS
- Proteomics of the lysosome
- (2008) Torben Lübke et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Lysosomal involvement in cell death and cancer
- (2008) Thomas Kirkegaard et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Principles of lysosomal membrane degradation
- (2008) Heike Schulze et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Lysosomal disorders: From storage to cellular damage
- (2008) Andrea Ballabio et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Sensitization to the Lysosomal Cell Death Pathway by Oncogene-Induced Down-regulation of Lysosome-Associated Membrane Proteins 1 and 2
- (2008) N. Fehrenbacher et al. CANCER RESEARCH
- Autophagy in the Pathogenesis of Disease
- (2008) Beth Levine et al. CELL
- The V-type H+-ATPase in vesicular trafficking: targeting, regulation and function
- (2008) Vladimir Marshansky et al. CURRENT OPINION IN CELL BIOLOGY
- Multivesicular bodies: co-ordinated progression to maturity
- (2008) Philip G Woodman et al. CURRENT OPINION IN CELL BIOLOGY
- Cysteine Cathepsins Trigger Caspase-dependent Cell Death through Cleavage of Bid and Antiapoptotic Bcl-2 Homologues
- (2008) Gabriela Droga-Mazovec et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Repair of injured plasma membrane by rapid Ca2+-dependent endocytosis
- (2008) Vincent Idone et al. JOURNAL OF CELL BIOLOGY
- Caspase-8 is activated by cathepsin D initiating neutrophil apoptosis during the resolution of inflammation
- (2008) Sébastien Conus et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Niemann-Pick disease type C1 is a sphingosine storage disease that causes deregulation of lysosomal calcium
- (2008) Emyr Lloyd-Evans et al. NATURE MEDICINE
- Cysteine cathepsin proteases as pharmacological targets in cancer
- (2007) Carmela Palermo et al. TRENDS IN PHARMACOLOGICAL SCIENCES
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