Harwinder Sidhu

United States Research

基金

评论了 Avenir Award Program for Genetics or Epigenetics of Substance Use Disorders (DP1 Clinical Trial Optional)
Excellent R01 opportunity for early-stage investors to research HIV/AIDS and for genetic/epigenetic studies. The deadline to apply is October 19, 2022.

期刊

评论了 PeerJ
PeerJ is an O'Reiley Media Inc./Sage Publications Journal with an impact factor of 2.984 (2020). You can even publish for free provided your institution has a PeerJ Publishing Partnership.

论文

评论了 Application of CRISPR/Cas9 in Alzheimer’s Disease
CRISPR/Cas9 is a powerful gene-editing tool. In this paper, the authors used it to induce Alzheimer's in mice to create an Alzheimer's disease model and to screen for pathogenic gene targets. Traditionally, Alzheimer's models are based on the transgenic expression of human APP.

论文

评论了 CRISPR/Cas9 therapeutics for liver diseases
CRISPR/Cas9 is a great tool that will potentially help millions of people. Its use for treating liver diseases is promising especially for metabolic and acquired liver disorders.

论文

评论了 Plasma Gamma-Glutamyltransferase (GGT) Activity in Inflammatory Bowel Disease
According to this paper, low plasma GGT levels are associated with Inflammatory Bowel Disease (IBD). Several other diseases are related to polymorphism of the GGT gene.

基金

评论了 New Investigator Research Grants
Great opportunity for new investigators to work on pediatrics, maternal health by Purdue and Wisconsin university. Trainees can apply too as co-investigators as long as there is a principal investigator who qualifies.

论文

评论了 Protein Microarray On-Demand: A Novel Protein Microarray System
Protein microarray are very effective in studying protein-protein interactions, protein-small molecule interactions. Their low cost and longer shelf-life makes them even more desirable option for studying protein chemistry.

论文

评论了 COVID-19 Real-time RTPCR: Does Positivity on Follow up RTPCR Always Imply Infectivity?
This article answers an important pandemic question. Positivity on RT-PCR does not necessarily imply infectivity. Infectivity depends on a person's viral load. Viral culture results indicated positivity during peak viral load and tested negative 8 days after infection even though the RT-PCR was still positive.

论文

评论了 Fluorescent labeling of NASBA amplified tmRNA molecules for microarray applications
This research paper discusses a novel approach that combines NASBA with microarray technology to test for specific pathogens in a variety of possible targets. The authors evaluated two different aaUTP salts to find out that the optimal concentration at 2mM resulted in the highest sensitivity.

期刊

评论了 ENZYME AND MICROBIAL TECHNOLOGY
Good quality biotechnology journal focusing on enzymes and microbiology!

论文

评论了 Enzyme Immobilization via Electrospinning
ELectrospinning and nano fibers are catching on for enzyme immobilization!

论文

评论了 MicroRNA panel in serum reveals novel diagnostic biomarkers for prostate cancer
Three panel miRNA panel as non invasive bio marker for diagnosing PC!

论文

评论了 Older age and diclofenac are associated with increased risk of upper gastrointestinal bleeding in gout patients
Close monitoring of gout patients administered with diclofenac is advised especially that of older age.