2019年发表

DNA complexes as an efficient gene anticancer drug delivery therapy

作者: -

发表期刊: Nucleic Acids as Gene Anticancer Drug Delivery Therapy

2019年发表

Distribution patterns of natural radionuclides and rare earth elements in marine sediments from the Red Sea, Egypt

作者: Atef El-Taher, Wael M. Badawy, Ashraf E.M. Khater, Hashem A. Madkour

发表期刊: Applied Radiation and Isotopes

2019年发表

Drug delivery systems as advanced nanotechnology

作者: -

发表期刊: Nucleic Acids as Gene Anticancer Drug Delivery Therapy

2019年发表

FDA and the medical device clinical drug trials

作者: -

发表期刊: Nucleic Acids as Gene Anticancer Drug Delivery Therapy

2019年发表

Immunotherapy with mRNA vaccination and immunomodulation nanomedicine for cancer therapy

作者: -

发表期刊: Nucleic Acids as Gene Anticancer Drug Delivery Therapy

2019年发表

Multiple delivery of drug-nucleic acid combinations for cancer treatment

作者: -

发表期刊: Nucleic Acids as Gene Anticancer Drug Delivery Therapy

2019年发表

Nanoparticle and polymeric nanoparticle-based targeted drug delivery systems

作者: -

发表期刊: Nucleic Acids as Gene Anticancer Drug Delivery Therapy

2019年发表

Nucleic acid medicines as green novel anticancer drugs

作者: -

发表期刊: Nucleic Acids as Gene Anticancer Drug Delivery Therapy

2018年发表

Applications of gold nanoparticles in medicine and therapy

gold nanoparticles medicine therapy Applications

作者: Loutfy H Madkour

发表期刊: Pharmacy & Pharmacology International Journal

论文简介:

The stability and dispersity of AuNMs in solution play a key role for the many applications. Most inorganic nanomaterials are not well dispersed in physiological buffers and require function-alization by thiols or surfactants to offer the stabilization forces. Furthermore, suficient blood circulation time is critical for both imaging and in vivo drug delivery. Localized surface Plasmon resonance (LSPR) is one of the most signiicant features of AuNMs. The AuNMs as reporters have been broadly applied into lateral low immunechromatographicalassay (LFICA) and enzyme-linked immunosorbent assay (ELISA), which is a well-established technology for analysis of the target analytes in food safety, clinical diagnosis, environmental monitoring, and medical science and so on. Au based nanomaterials (AuNMs) are known to possess many attractive features such as unique electrical, optical and catalytic properties as well as excellent biocompatibility. In this review, we summarize the current advancement on application of AuNMs in analytical sciences based on their local surface plasmon resonance, luorescence and electrochemistry properties. AuNMs based imaging and therapy in biomolecules is explained. As one of the most reliable imaging modes, computed tomography (CT), X-ray and SERS imaging has been widely used owing to its high spatial and density resolution. We end the review by a discussion of the conjugation between gold nanoparticles with other kinds of nanoparticles such as other metals and carbon nano structures. Finally, future development in this research area is also prospected.

2018年发表

Biogenic– Biosynthesis Metallic Nanoparticles (MNPs) for Pharmacological, Biomedical and Environmental Nanobiotechnological Applications

Biogenic– Biosynthesis Metallic Nanoparticles Pharmacological Nanobiotechnological Applications

作者: Loutfy H. Madkour

发表期刊: Chronicles of Pharmaceutical Science

论文简介:

Abstract In future, the biogenic– biosynthesis MNPs have wide perspective synthesis in healthcare, sustainable and renewable energy and other commercial products. MNPs produced by nanotechnology have received global attention due to their extensive applications in the biomedical and physiochemical fields. Biomolecules present in live plants, plant extracts and microorganisms such as: bacteria, fungi, seaweeds, actinomycetes, algae and microalgae can be used to reduce metal ions to MNPs in a single-step and green synthesis process. Biological green synthesis of MNPs has been always beneficial, more economical, energy efficient and eco-friendly approach, which is free of toxic contaminates as required in therapeutic applications. The biosynthesis reduction of metal ion to base metal is quite rapid, readily conducted at room temperature, pressure and easily scaled up. The reducing agents involved include the various water-soluble plant metabolites (e.g. alkaloids, phenolic compounds, terpenoids, flavonoids, saponins, steroids, tannins and other nutritional compounds) and co-enzymes. The polysaccharides, proteins and lipids present in the algal membranes act as capping agents and thus limit the use of non-biodegradable commercial surfactants, which are difficult to remove after the synthesis of MNPs. Metallic nanoparticles viz. cobalt, copper, silver, gold, platinum, zirconium, palladium, iron, cadmium and metal oxides such as titanium oxide, zinc oxide, magnetite, etc. have been the particular focus of green biosynthesis. Here we review the methods of making MNPs using plants extracts and microorganisms. Methods of particle characterization, biomedical and environmental applications of MNPs are reviewed. In the near future, the application of clean, non-toxic, and ecofriendly nanostructured material will be possible in industry and biomedicine. Volume 2 • Issue 1 • 2018 Page 384 to 444 Keywords: Biogenic–Biosynthesis; MNPs; Plant extracts; Microorganisms; Pharmacological; Biomedical; Commercial applications