2019年发表

Nucleic Acids as Gene Anticancer Drug Delivery Therapy

Nucleic Acids Gene Anticancer Drug Delivery Therapy

作者: Loutfy H. Madkour

发表期刊: Copyright © 2019 Elsevier Inc. All rights reserved.

论文简介:

Nucleic Acids as Gene Anticancer Drug Delivery Therapy highlights the most recent developments in cancer treatment using nucleic acids, nanoparticles and polymer nanoparticles for genomic nanocarriers as drug delivery, including promising opportunities for targeted and combination therapy. The development of a wide spectrum of nanoscale technologies is beginning to change the scientific landscape in terms of disease diagnosis, treatment, and prevention. This book presents the use of nanotechnology for medical applications, focusing on its use for anticancer drug delivery. Various intelligent drug delivery systems such as inorganic nanoparticles and polymer-based drug delivery are discussed. The use of smart drug delivery systems seems to be a promising approach for developing intelligent therapeutic systems for cancer immunotherapies and is discussed in detail along with nucleic acid-targeted drug delivery combination therapy for cancer. Nucleic Acids as Gene Anticancer Drug Delivery Therapy will be a useful reference for pharmaceutical scientists, pharmacologiests, and those involved in nanotechnology and cancer research.

2019年发表

Function of Reactive Oxygen Species (ROS) Inside the Living Organisms and Sources of Oxidants

Reactive Oxygen Species e Living Organisms Sources Oxidants

作者: Loutfy H Madkour

发表期刊: Pharma Sci Analytical Res J 2019, 2(2): 180023.

论文简介:

Reactive oxygen species (ROS) is a generic name given to a variety of molecules and free radicals derived from molecular oxygen. The reduction of oxygen produces relatively stable intermediates. One electron-reduction produces superoxide anion, which is the precursor of most ROS. As most commonly used, ROS in this chapter refer to superoxide, hydrogen peroxide and their derivatives such as the hydroxyl radical. Reactive oxygen species (ROS) were initially recognized as toxic by-products of aerobic metabolism. In recent years, it has become apparent that ROS plays an important signaling role in plants, controlling processes such as growth, development and especially response to biotic and abiotic environmental stimuli. ROS include free radicals such as superoxide anion (O2 ●—), hydroxyl radical (●OH), as well as nonradical molecules like hydrogen peroxide (H2O2), singlet oxygen (1O2), and so forth. Stepwise reduction of molecular oxygen (O2) by high-energy exposure or electron-transfer reactions leads to production of the highly reactive ROS. Reactive oxygen species (ROS) are produced by living organisms as a result of normal cellular metabolism and environmental factors, such as air pollutants or cigarette smoke. ROS are highly reactive molecules and can damage cell structures such as carbohydrates, nucleic acids, lipids, and proteins and alter their functions. Keywords: Reactive oxygen species (ROS); Highly reactive molecules; O2 ●— ; 1O2; ●OH; H2O2; Living organisms

2019年发表

Nucleic Acids as Gene Anticancer Drug Delivery Therapy 1st Edition, Kindle Edition by Loutfy H. Madkour (Author)

Nucleic Acids Gene Anticancer Drug Delivery Therapy

作者: Loutfy H. Madkour

发表期刊: Publisher ‏ : ‎ Academic Press; 1st edition (27 Aug. 2019)

论文简介:

Nucleic Acids as Gene Anticancer Drug Delivery Therapy highlights the most recent developments in cancer treatment using nucleic acids, nanoparticles and polymer nanoparticles for genomic nanocarriers as drug delivery, including promising opportunities for targeted and combination therapy. The development of a wide spectrum of nanoscale technologies is beginning to change the scientific landscape in terms of disease diagnosis, treatment, and prevention. This book presents the use of nanotechnology for medical applications, focusing on its use for anticancer drug delivery. Various intelligent drug delivery systems such as inorganic nanoparticles and polymer-based drug delivery are discussed. The use of smart drug delivery systems seems to be a promising approach for developing intelligent therapeutic systems for cancer immunotherapies and is discussed in detail along with nucleic acid-targeted drug delivery combination therapy for cancer. Nucleic Acids as Gene Anticancer Drug Delivery Therapy will be a useful reference for pharmaceutical scientists, pharmacologiests, and those involved in nanotechnology and cancer research. Discusses intelligent drug delivery systems such as inorganic nanoparticles and polymer-based drug delivery Contains a comprehensive comparison of various delivery systems, listing their advantages and limitations Presents combination therapy as a new hope for enhancing current gene-based treatment efficacy

2019年发表

Nanoelectronic Materials: Fundamentals and Applications: 116 (Advanced Structured Materials, 116) Hardcover – 16 July 2019

Nanoelectronic Materials Fundamentals Applications

作者: Loutfy H. Madkour

发表期刊: Springer; 1st ed. 2019 edition (16 July 2019) ISBN-10 3030216209 ISBN-13 978-3030216207

论文简介:

This book presents synthesis techniques for the preparation of low-dimensional nanomaterials including 0D (quantum dots), 1D (nanowires, nanotubes) and 2D (thin films, few layers), as well as their potential applications in nanoelectronic systems. It focuses on the size effects involved in the transition from bulk materials to nanomaterials; the electronic properties of nanoscale devices; and different classes of nanomaterials from microelectronics to nanoelectronics, to molecular electronics. Furthermore, it demonstrates the structural stability, physical, chemical, magnetic, optical, electrical, thermal, electronic and mechanical properties of the nanomaterials. Subsequent chapters address their characterization, fabrication techniques from lab-scale to mass production, and functionality. In turn, the book considers the environmental impact of nanotechnology and novel applications in the mechanical industries, energy harvesting, clean energy, manufacturing materials, electronics, transistors, health and medical therapy. In closing, it addresses the combination of biological systems with nanoelectronics and highlights examples of nanoelectronic–cell interfaces and other advanced medical applications. The book answers the following questions: • What is different at the nanoscale? • What is new about nanoscience? • What are nanomaterials (NMs)? • What are the fundamental issues in nanomaterials? • Where are nanomaterials found? • What nanomaterials exist in nature? • What is the importance of NMs in our lives? • Why so much interest in nanomaterials? • What is at nanoscale in nanomaterials? • What is graphene? • Are pure low-dimensional systems interesting and worth pursuing? • Are nanotechnology products currently available? • What are sensors? • How can Artificial Intelligence (AI) and nanotechnology work together? • What are the recent advances in nanoelectronic materials?

2019年发表

Phenolic Constituents, Antimicrobial, Antioxidant, and Anticancer Activities of Ethyl Acetate and n-Butanol Extracts of Senna italica

作者: -

发表期刊: Acta Chromatographica

2019年发表

Polymer nanoparticle drug-nucleic acid combinations

作者: -

发表期刊: Nucleic Acids as Gene Anticancer Drug Delivery Therapy

2019年发表

Solvent-accessible surfaces of proteins and nucleic acids

作者: -

发表期刊: Nucleic Acids as Gene Anticancer Drug Delivery Therapy

2019年发表

Structures of quadruplex nucleic acids and their drug complexes

作者: -

发表期刊: Nucleic Acids as Gene Anticancer Drug Delivery Therapy

2019年发表

Targeting mechanisms of polymeric micelles for delivery of siRNA in cancer therapy

作者: -

发表期刊: Nucleic Acids as Gene Anticancer Drug Delivery Therapy

2019年发表

Therapeutic applications of siRNA gene delivery systems

作者: -

发表期刊: Nucleic Acids as Gene Anticancer Drug Delivery Therapy