Pharmacological reduction of mucosal but not neuronal serotonin opposes inflammation in mouse intestine

Editorial: Abnormal Immune Regulation and Low-Grade Inflammation in IBS: Does One Size Fit All?

(2012) Max Schmulson et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Irritable Bowel Syndrome: Methods, Mechanisms, and Pathophysiology. Genetic epidemiology and pharmacogenetics in irritable bowel syndrome

(2012) Michael Camilleri et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Global Prevalence of and Risk Factors for Irritable Bowel Syndrome: A Meta-analysis

(2012) Rebecca M. Lovell et al.   Clinical Gastroenterology and Hepatology

Neuronal Serotonin Regulates Growth of the Intestinal Mucosa in Mice

(2012) Erica R. Gross et al.   GASTROENTEROLOGY

A Global Perspective on Irritable Bowel Syndrome

(2012) Eamonn M. M. Quigley et al.   JOURNAL OF CLINICAL GASTROENTEROLOGY

Intestinal barrier function in health and gastrointestinal disease

(2012) M. Camilleri et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Severity in Irritable Bowel Syndrome: A Rome Foundation Working Team Report

(2011) Douglas A Drossman et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

The Tryptophan Hydroxylase Inhibitor LX1031 Shows Clinical Benefit in Patients With Nonconstipating Irritable Bowel Syndrome

(2011) Philip M. Brown et al.   GASTROENTEROLOGY

Enteric Neuronal Density Contributes to the Severity of Intestinal Inflammation

(2011) Kara Gross Margolis et al.   GASTROENTEROLOGY

Increasing Incidence and Prevalence of the Inflammatory Bowel Diseases With Time, Based on Systematic Review

(2011) Natalie A. Molodecky et al.   GASTROENTEROLOGY

Quality of Life in Patients With Irritable Bowel Syndrome

(2011) Hubert Mönnikes   JOURNAL OF CLINICAL GASTROENTEROLOGY

Essential Roles of Enteric Neuronal Serotonin in Gastrointestinal Motility and the Development/Survival of Enteric Dopaminergic Neurons

(2011) Z. Li et al.   JOURNAL OF NEUROSCIENCE

Pharmacological inhibition of gut-derived serotonin synthesis is a potential bone anabolic treatment for osteoporosis

(2010) Vijay K Yadav et al.   NATURE MEDICINE

Enhancement of intestinal inflammation in mice lacking interleukin 10 by deletion of the serotonin reuptake transporter

(2010) S. Haub et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Deletion of the serotonin transporter in rats disturbs serotonin homeostasis without impairing liver regeneration

(2009) Ramadhan B. Matondo et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Substituted 3-(4-(1,3,5-triazin-2-yl)-phenyl)-2-aminopropanoic acids as novel tryptophan hydroxylase inhibitors

(2009) Haihong Jin et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Spatio-temporal expression of tryptophan hydroxylase isoforms in murine and human brain: Convergent data from Tph2 knockout mice

(2009) Lise Gutknecht et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Serotonin Has a Key Role in Pathogenesis of Experimental Colitis

(2009) Jean–Eric Ghia et al.   GASTROENTEROLOGY

Release of 5-Hydroxytryptamine From the Mucosa Is Not Required for the Generation or Propagation of Colonic Migrating Motor Complexes

(2009) Damien J. Keating et al.   GASTROENTEROLOGY

IL1β- and LPS-induced serotonin secretion is increased in EC cells derived from Crohn’s disease

(2009) m. kidd et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Role of serotonin in intestinal inflammation: knockout of serotonin reuptake transporter exacerbates 2,4,6-trinitrobenzene sulfonic acid colitis in mice

(2008) Stephan C. Bischoff et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Deficiency of brain 5-HT synthesis but serotonergic neuron formation in Tph2 knockout mice

(2008) Lise Gutknecht et al.   JOURNAL OF NEURAL TRANSMISSION

Discovery and Characterization of Novel Tryptophan Hydroxylase Inhibitors That Selectively Inhibit Serotonin Synthesis in the Gastrointestinal Tract

(2008) Q. Liu et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Strain-specific genetics, anatomy and function of enteric neural serotonergic pathways in inbred mice

(2008) Kathleen B. Neal et al.   JOURNAL OF PHYSIOLOGY-LONDON

Genetic Disruption of Both Tryptophan Hydroxylase Genes Dramatically Reduces Serotonin and Affects Behavior in Models Sensitive to Antidepressants

(2008) Katerina V. Savelieva et al.   PLoS One

Symbiotic gut microbes modulate human metabolic phenotypes

(2008) M. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA