p21 promotes sustained liver regeneration and hepatocarcinogenesis in chronic cholestatic liver injury

The degree of liver injury determines the role of p21 in liver regeneration and hepatocarcinogenesis in mice

(2013) Laura Elisa Buitrago-Molina et al.   HEPATOLOGY

HSCs play a distinct role in different phases of oval cell-mediated liver regeneration

(2012) Lin Chen et al.   CELL BIOCHEMISTRY AND FUNCTION

Disruption of Trp53 in Livers of Mice Induces Formation of Carcinomas With Bilineal Differentiation

(2012) Sarah–Fee Katz et al.   GASTROENTEROLOGY

Liver Failure After Extended Hepatectomy in Mice Is Mediated by a p21-Dependent Barrier to Liver Regeneration

(2012) Kuno Lehmann et al.   GASTROENTEROLOGY

Comparison of hepatocellular carcinoma in American and Asian patients by tissue array analysis

(2012) Tae-Jin Song et al.   JOURNAL OF SURGICAL ONCOLOGY

Prospective isolation of a bipotential clonogenic liver progenitor cell in adult mice

(2011) C. Dorrell et al.   GENES & DEVELOPMENT

Fate tracing of mature hepatocytes in mouse liver homeostasis and regeneration

(2011) Yann Malato et al.   JOURNAL OF CLINICAL INVESTIGATION

Hepatocyte IKKβ/NF-κB Inhibits Tumor Promotion and Progression by Preventing Oxidative Stress-Driven STAT3 Activation

(2010) Guobin He et al.   CANCER CELL

Signal Transducer and Activator of Transcription 3 Protects From Liver Injury and Fibrosis in a Mouse Model of Sclerosing Cholangitis

(2010) Markus Mair et al.   GASTROENTEROLOGY

Accelerated carcinogenesis following liver regeneration is associated with chronic inflammation-induced double-strand DNA breaks

(2010) H. Barash et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Enrichment and Clonal Culture of Progenitor Cells During Mouse Postnatal Liver Development in Mice

(2009) Akihide Kamiya et al.   GASTROENTEROLOGY

Loss of p21 Permits Carcinogenesis from Chronically Damaged Liver and Kidney Epithelial Cells despite Unchecked Apoptosis

(2008) Holger Willenbring et al.   CANCER CELL

Proliferation of human HCC cells and chemically induced mouse liver cancers requires JNK1-dependent p21 downregulation

(2008) Lijian Hui et al.   JOURNAL OF CLINICAL INVESTIGATION