Genetic factors conferring an increased susceptibility to develop Crohn's disease also influence disease phenotype: results from the IBDchip European Project

Has There Been a Change in the Natural History of Crohn's Disease? Surgical Rates and Medical Management in a Population-Based Inception Cohort from Western Hungary Between 1977–2009

(2012) Peter Laszlo Lakatos et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

The Prognostic Power of the NOD2 Genotype for Complicated Crohn's Disease: A Meta-Analysis

(2011) Jeremy Adler et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

High-throughput clone library analysis of the mucosa-associated microbiota reveals dysbiosis and differences between inflamed and non-inflamed regions of the intestine in inflammatory bowel disease

(2011) Alan W Walker et al.   BMC MICROBIOLOGY

Dysbiosis of the faecal microbiota in patients with Crohn's disease and their unaffected relatives

(2011) M. Joossens et al.   GUT

The JAK2 variant rs10758669 in Crohn’s disease: altering the intestinal barrier as one mechanism of action

(2011) Matthias Prager et al.   INTERNATIONAL JOURNAL OF COLORECTAL DISEASE

Natural history of Crohn's disease in a population-based cohort from Cardiff (1986-2003): a study of changes in medical treatment and surgical resection rates

(2010) A. V. Ramadas et al.   GUT

The presence of fistulas and NOD2 homozygosity strongly predict intestinal stenosis in Crohn’s disease independent of the IL23R genotype

(2010) Matthias Jürgens et al.   JOURNAL OF GASTROENTEROLOGY

Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci

(2010) Andre Franke et al.   NATURE GENETICS

Molecular Reclassification of Crohn's Disease by Cluster Analysis of Genetic Variants

(2010) Isabelle Cleynen et al.   PLoS One

Nod1 and Nod2 direct autophagy by recruiting ATG16L1 to the plasma membrane at the site of bacterial entry

(2009) Leonardo H Travassos et al.   NATURE IMMUNOLOGY

NOD2 stimulation induces autophagy in dendritic cells influencing bacterial handling and antigen presentation

(2009) Rachel Cooney et al.   NATURE MEDICINE

XBP1 Links ER Stress to Intestinal Inflammation and Confers Genetic Risk for Human Inflammatory Bowel Disease

(2008) Arthur Kaser et al.   CELL

Molecular prediction of disease risk and severity in a large Dutch Crohn's disease cohort

(2008) R K Weersma et al.   GUT

Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease

(2008) Jeffrey C Barrett et al.   NATURE GENETICS

Predictors of severe Crohn's disease

(2008) Catherine Loly et al.   SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY