Glycans and galectins in prostate cancer biology, angiogenesis and metastasis

Synthetic Galectin-3 Inhibitor Increases Metastatic Cancer Cell Sensitivity to Taxol-Induced Apoptosis In Vitro and In Vivo

(2015) Vladislav V. Glinsky et al.   NEOPLASIA

Inhibition of Prostate Cancer Bone Metastasis by Synthetic TF Antigen Mimic/Galectin-3 Inhibitor Lactulose-l-Leucine

(2015) Olga V. Glinskii et al.   NEOPLASIA

Glycosylation-Dependent Lectin-Receptor Interactions Preserve Angiogenesis in Anti-VEGF Refractory Tumors

(2014) Diego O. Croci et al.   CELL

Emerging Principles for the Therapeutic Exploitation of Glycosylation

(2014) Martin Dalziel et al.   SCIENCE

Human fucosyltransferase 6 enables prostate cancer metastasis to bone

(2013) J Li et al.   BRITISH JOURNAL OF CANCER

Aberrant PSA glycosylation—a sweet predictor of prostate cancer

(2013) Sarah Gilgunn et al.   Nature Reviews Urology

VEGFR1 and VEGFR2 Involvement in Extracellular Galectin-1- and Galectin-3-Induced Angiogenesis

(2013) Nicky D'Haene et al.   PLoS One

Cod glycopeptide with picomolar affinity to galectin-3 suppresses T-cell apoptosis and prostate cancer metastasis

(2013) P. Guha et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Overexpression of O-GlcNAc by prostate cancer cells is significantly associated with poor prognosis of patients

(2013) T Kamigaito et al.   PROSTATE CANCER AND PROSTATIC DISEASES

The significance of galectin-3 as a new basal cell marker in prostate cancer

(2013) Y Wang et al.   Cell Death & Disease

Delineating the "galectin signature" of the tumor microenvironment

(2013) Daniel Compagno et al.   OncoImmunology

A Unique Galectin Signature in Human Prostate Cancer Progression Suggests Galectin-1 as a Key Target for Treatment of Advanced Disease

(2012) D. J. Laderach et al.   CANCER RESEARCH

Human Prostate Cancer in a Clinically Relevant Xenograft Mouse Model: Identification of β(1,6)-Branched Oligosaccharides as a Marker of Tumor Progression

(2012) Tobias Lange et al.   CLINICAL CANCER RESEARCH

Regulatory Circuits Mediated by Lectin-Glycan Interactions in Autoimmunity and Cancer

(2012) Gabriel A. Rabinovich et al.   IMMUNITY

Tyrosine-phosphorylated Galectin-3 Protein Is Resistant to Prostate-specific Antigen (PSA) Cleavage

(2012) Vitaly Balan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Critical Role ofO-Linked β-N-Acetylglucosamine Transferase in Prostate Cancer Invasion, Angiogenesis, and Metastasis

(2012) Thomas P. Lynch et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Disrupting galectin-1 interactions with N-glycans suppresses hypoxia-driven angiogenesis and tumorigenesis in Kaposi’s sarcoma

(2012) Diego O. Croci et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Galectin-3 expression in prostate cancer and benign prostate tissues: correlation with biochemical recurrence

(2012) Judith S. Knapp et al.   WORLD JOURNAL OF UROLOGY

Defining putative glycan cancer biomarkers by MS

(2012) Yehia Mechref et al.   Bioanalysis

When Galectins Recognize Glycans: From Biochemistry to Physiology and Back Again

(2011) Santiago Di Lella et al.   BIOCHEMISTRY

Global cancer statistics

(2011) Ahmedin Jemal et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Tumor Cells Secrete Galectin-1 to Enhance Endothelial Cell Activity

(2010) V. L. Thijssen et al.   CANCER RESEARCH

Knockdown of fucosyltransferase III disrupts the adhesion of circulating cancer cells to E-selectin without affecting hematopoietic cell adhesion

(2010) Xiaoyan Yin et al.   CARBOHYDRATE RESEARCH

Modulation of endothelial cell migration and angiogenesis: a novel function for the “tandem-repeat” lectin galectin-8

(2010) Víctor M. Cárdenas Delgado et al.   FASEB JOURNAL

Core fucosylation and  2-3 sialylation in serum N-glycome is significantly increased in prostate cancer comparing to benign prostate hyperplasia

(2010) R. Saldova et al.   GLYCOBIOLOGY

Cleavage of galectin-3 by matrix metalloproteases induces angiogenesis in breast cancer

(2010) Pratima Nangia-Makker et al.   INTERNATIONAL JOURNAL OF CANCER

Interaction between circulating galectin-3 and cancer-associated MUC1 enhances tumour cell homotypic aggregation and prevents anoikis

(2010) Qicheng Zhao et al.   Molecular Cancer

A systematic approach to protein glycosylation analysis: a path through the maze

(2010) Karina Mariño et al.   Nature Chemical Biology

Galectin-3 is a substrate for prostate specific antigen (PSA) in human seminal plasma

(2010) Sarika Saraswati et al.   PROSTATE

Regulation of Prostate Cancer Progression by Galectin-3

(2009) Yi Wang et al.   AMERICAN JOURNAL OF PATHOLOGY

Galectin-8 interacts with podoplanin and modulates lymphatic endothelial cell functions

(2009) Leah N. Cueni et al.   EXPERIMENTAL CELL RESEARCH

 1,2-Fucosylated and  -N-acetylgalactosaminylated prostate-specific antigen as an efficient marker of prostatic cancer

(2009) K. Fukushima et al.   GLYCOBIOLOGY

Core3O-Glycan Synthase Suppresses Tumor Formation and Metastasis of Prostate Carcinoma PC3 and LNCaP Cells through Down-regulation of α2β1 Integrin Complex

(2009) Seung Ho Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Analysis of glycosyltransferase expression in metastatic prostate cancer cells capable of rolling activity on microvascular endothelial (E)-selectin

(2008) S. R Barthel et al.   GLYCOBIOLOGY

Sialylation of  1 Integrins Blocks Cell Adhesion to Galectin-3 and Protects Cells against Galectin-3-induced Apoptosis

(2008) Y. Zhuo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Protein-glycan interactions in the control of innate and adaptive immune responses

(2008) Yvette van Kooyk et al.   NATURE IMMUNOLOGY

Frontiers in glycomics: Bioinformatics and biomarkers in disease An NIH White Paper prepared from discussions by the focus groups at a workshop on the NIH campus, Bethesda MD (September 11–13, 2006)

(2007) Nicolle H. Packer et al.   PROTEOMICS