Role of glycans and glycosyltransferases in the regulation of Notch signaling

Endocytic Internalization Routes Required for Delta/Notch Signaling

(2010) Sarah L. Windler et al.   CURRENT BIOLOGY

Overexpression of Human CAP10-Like Protein 46 KD in T-Acute Lymphoblastic Leukemia and Acute Myelogenous Leukemia

(2010) Youxin Wang et al.   Genetic Testing and Molecular Biomarkers

Notch ligand activity is modulated by glycosphingolipid membrane composition inDrosophila melanogaster

(2010) Sophie Hamel et al.   JOURNAL OF CELL BIOLOGY

Notch1 Signaling in FIZZ1 Induction of Myofibroblast Differentiation

(2009) Tianju Liu et al.   AMERICAN JOURNAL OF PATHOLOGY

Notch signalling in the paraxial mesoderm is most sensitive to reduced Pofut1 levels during early mouse development

(2009) Karin Schuster-Gossler et al.   BMC DEVELOPMENTAL BIOLOGY

Origin and evolution of the Notch signalling pathway: an overview from eukaryotic genomes

(2009) Eve Gazave et al.   BMC EVOLUTIONARY BIOLOGY

Gain-of-function mutations and copy number increases of Notch2 in diffuse large B-cell lymphoma

(2009) Suk-young Lee et al.   CANCER SCIENCE

The Notch Ligands Dll4 and Jagged1 Have Opposing Effects on Angiogenesis

(2009) Rui Benedito et al.   CELL

The Canonical Notch Signaling Pathway: Unfolding the Activation Mechanism

(2009) Raphael Kopan et al.   CELL

Notch Signaling: The Core Pathway and Its Posttranslational Regulation

(2009) Mark E. Fortini   DEVELOPMENTAL CELL

Manic fringe is not required for embryonic development, and fringe family members do not exhibit redundant functions in the axial skeleton, limb, or hindbrain

(2009) Jennifer L. Moran et al.   DEVELOPMENTAL DYNAMICS

Mammalian Notch is modified by d-Xyl-α1-3-d-Xyl-α1-3-d-Glc-β1-O-Ser: Implementation of a method to study O-glucosylation

(2009) Garrett E Whitworth et al.   GLYCOBIOLOGY

Lunatic and Manic Fringe Cooperatively Enhance Marginal Zone B Cell Precursor Competition for Delta-like 1 in Splenic Endothelial Niches

(2009) Joanne B. Tan et al.   IMMUNITY

Metalloprotease ADAM10 Is Required for Notch1 Site 2 Cleavage

(2009) Geert van Tetering et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification of Glycosyltransferase 8 Family Members as Xylosyltransferases Acting onO-Glucosylated Notch Epidermal Growth Factor Repeats

(2009) Maya K. Sethi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Two Pathways for Importing GDP-fucose into the Endoplasmic Reticulum Lumen Function Redundantly in theO-Fucosylation of Notch inDrosophila

(2009) Hiroyuki O. Ishikawa et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Notch updated

(2009) An-Chi Tien et al.   JOURNAL OF CELL BIOLOGY

Selective Use of ADAM10 and ADAM17 in Activation of Notch1 Signaling

(2009) E. C. Bozkulak et al.   MOLECULAR AND CELLULAR BIOLOGY

De novo copy number variants identify new genes and loci in isolated sporadic tetralogy of Fallot

(2009) Steven C Greenway et al.   NATURE GENETICS

Effects of S1 Cleavage on the Structure, Surface Export, and Signaling Activity of Human Notch1 and Notch2

(2009) Wendy R. Gordon et al.   PLoS One

In Vivo Analysis of the Notch Receptor S1 Cleavage

(2009) Robert J. Lake et al.   PLoS One

Embryonic arrest at midgestation and disruption of Notch signaling produced by the absence of both epsin 1 and epsin 2 in mice

(2009) H. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Notch-dependent control of myelopoiesis is regulated by fucosylation

(2008) L. Zhou et al.   BLOOD

Structure of the Notch1-negative regulatory region: implications for normal activation and pathogenic signaling in T-ALL

(2008) W. R. Gordon et al.   BLOOD

Contributions of chaperone and glycosyltransferase activities of O-fucosyltransferase 1 to Notch signaling

(2008) Tetsuya Okajima et al.   BMC BIOLOGY

Competition between Delta and the Abruptex domain of Notch

(2008) Zifei Pei et al.   BMC DEVELOPMENTAL BIOLOGY

Emerging role of Notch in stem cells and cancer

(2008) Zhiwei Wang et al.   CANCER LETTERS

A Notch Sweeter

(2008) Kenneth D. Irvine   CELL

Rumi Is a CAP10 Domain Glycosyltransferase that Modifies Notch and Is Required for Notch Signaling

(2008) Melih Acar et al.   CELL

Bile duct proliferation in Jag1/fringe heterozygous mice identifies candidate modifiers of the alagille syndrome hepatic phenotype

(2008) Matthew J. Ryan et al.   HEPATOLOGY

Mutation of HAIRY-AND-ENHANCER-OF-SPLIT-7 in humans causes spondylocostal dysostosis

(2008) D. B. Sparrow et al.   HUMAN MOLECULAR GENETICS

NOTCH1 mutations in individuals with left ventricular outflow tract malformations reduce ligand-induced signaling

(2008) K. L. McBride et al.   HUMAN MOLECULAR GENETICS

Role of unusual O-glycans in intercellular signaling

(2008) Kelvin B. Luther et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Biological Functions of Glycosyltransferase Genes Involved in O-fucose Glycan Synthesis

(2008) Tetsuya Okajima et al.   JOURNAL OF BIOCHEMISTRY

Roles of Pofut1 andO-Fucose in Mammalian Notch Signaling

(2008) Mark Stahl et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Functional UDP-xylose Transport across the Endoplasmic Reticulum/Golgi Membrane in a Chinese Hamster Ovary Cell Mutant Defective in UDP-xylose Synthase

(2008) Hans Bakker et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

O-LinkedN-Acetylglucosamine Is Present on the Extracellular Domain of Notch Receptors

(2008) Aiko Matsuura et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The molecular logic of Notch signaling - a structural and biochemical perspective

(2008) W. R. Gordon et al.   JOURNAL OF CELL SCIENCE

Pofut1 is required for the proper localization of the Notch receptor during mouse development

(2008) Yoshiaki Okamura et al.   MECHANISMS OF DEVELOPMENT

The O-fucose glycan in the ligand-binding domain of Notch1 regulates embryogenesis and T cell development

(2008) C. Ge et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA