Suppression of TDO-mediated tryptophan catabolism in glioblastoma cells by a steroid-responsive FKBP52-dependent pathway

The kynurenine pathway as a therapeutic target in cognitive and neurodegenerative disorders

(2013) Trevor W Stone et al.   BRITISH JOURNAL OF PHARMACOLOGY

Expression of Tryptophan 2,3-Dioxygenase and Production of Kynurenine Pathway Metabolites in Triple Transgenic Mice and Human Alzheimer's Disease Brain

(2013) Wei Wu et al.   PLoS One

Tryptophan Catabolism in Cancer: Beyond IDO and Tryptophan Depletion

(2012) M. Platten et al.   CANCER RESEARCH

Indoleamine 2,3-dioxygenase: From catalyst to signaling function

(2012) Francesca Fallarino et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

An integrative model links multiple inputs and signaling pathways to the onset of DNA synthesis in hepatocytes

(2012) Jérémy Huard et al.   FEBS Journal

High-throughput SNP-based authentication of human cell lines

(2012) Felipe Castro et al.   INTERNATIONAL JOURNAL OF CANCER

Promotion of Glioblastoma Cell Motility by Enhancer of Zeste Homolog 2 (EZH2) Is Mediated by AXL Receptor Kinase

(2012) Martina Ott et al.   PLoS One

Reversal of tumoral immune resistance by inhibition of tryptophan 2,3-dioxygenase

(2012) L. Pilotte et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Delaying aging and the aging-associated decline in protein homeostasis by inhibition of tryptophan degradation

(2012) A. T. van der Goot et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IDO Is a Nodal Pathogenic Driver of Lung Cancer and Metastasis Development

(2012) Courtney Smith et al.   Cancer Discovery

The Kynurenine Pathway Modulates Neurodegeneration in a Drosophila Model of Huntington's Disease

(2011) Susanna Campesan et al.   CURRENT BIOLOGY

Steroid up-regulation of FKBP51 and its role in hormone signaling

(2011) Tiina Jääskeläinen et al.   CURRENT OPINION IN PHARMACOLOGY

FKBP51—a selective modulator of glucocorticoid and androgen sensitivity

(2011) Lance A Stechschulte et al.   CURRENT OPINION IN PHARMACOLOGY

Regulation of steroid hormone receptor function by the 52-kDa FK506-binding protein (FKBP52)

(2011) Jeffrey C Sivils et al.   CURRENT OPINION IN PHARMACOLOGY

Extension of life span of Drosophila melanogaster by the inhibitors of tryptophan-kynurenine metabolism

(2011) Gregory F. Oxenkrug et al.   FLY

The brain tumor microenvironment

(2011) Nikki A. Charles et al.   GLIA

The liver-specific microRNA miR-122 controls systemic iron homeostasis in mice

(2011) Mirco Castoldi et al.   JOURNAL OF CLINICAL INVESTIGATION

An endogenous tumour-promoting ligand of the human aryl hydrocarbon receptor

(2011) Christiane A. Opitz et al.   NATURE

Why tumours eat tryptophan

(2011) George C. Prendergast   NATURE

Indoleamine 2,3-dioxygenase is a signaling protein in long-term tolerance by dendritic cells

(2011) Maria T Pallotta et al.   NATURE IMMUNOLOGY

Imatinib potentiates antitumor T cell responses in gastrointestinal stromal tumor through the inhibition of Ido

(2011) Vinod P Balachandran et al.   NATURE MEDICINE

Susceptibility to Diet-Induced Hepatic Steatosis and Glucocorticoid Resistance in FK506-Binding Protein 52-Deficient Mice

(2010) Manya Warrier et al.   ENDOCRINOLOGY

A novel far-red bimolecular fluorescence complementation system that allows for efficient visualization of protein interactions under physiological conditions

(2009) Jun Chu et al.   BIOSENSORS & BIOELECTRONICS

The extended life span of Drosophila melanogaster eye-color (white and vermilion) mutants with impaired formation of kynurenine

(2009) Gregory F. Oxenkrug   JOURNAL OF NEURAL TRANSMISSION

Lewisx and  2,3-Sialyl Glycans and Their Receptors TAG-1, Contactin, and L1 Mediate CD24-Dependent Neurite Outgrowth

(2009) A. Lieberoth et al.   JOURNAL OF NEUROSCIENCE

High-throughput detection and multiplex identification of cell contaminations

(2009) M. Schmitt et al.   NUCLEIC ACIDS RESEARCH

Tryptophan 2,3-dioxygenase is a key modulator of physiological neurogenesis and anxiety-related behavior in mice

(2009) Masaaki Kanai et al.   Molecular Brain

Malignant Gliomas in Adults

(2008) Patrick Y. Wen et al.   NEW ENGLAND JOURNAL OF MEDICINE