Inflammasome activation restrictsLegionella pneumophilareplication in primary microglial cells through flagellin detection

Evaluating the role of Toll-like receptors in diseases of the central nervous system

(2011) Michael Carty et al.   BIOCHEMICAL PHARMACOLOGY

The NLRP3 Inflammasome Contributes to Brain Injury in Pneumococcal Meningitis and Is Activated through ATP-Dependent Lysosomal Cathepsin B Release

(2011) Tobias Hoegen et al.   JOURNAL OF IMMUNOLOGY

Inflammasome activation and IL-1β/IL-18 processing are influenced by distinct pathways in microglia

(2011) Richa Hanamsagar et al.   JOURNAL OF NEUROCHEMISTRY

The NLRC4 inflammasome receptors for bacterial flagellin and type III secretion apparatus

(2011) Yue Zhao et al.   NATURE

Innate immune recognition of bacterial ligands by NAIPs determines inflammasome specificity

(2011) Eric M. Kofoed et al.   NATURE

Non-canonical inflammasome activation targets caspase-11

(2011) Nobuhiko Kayagaki et al.   NATURE

Physiology of Microglia

(2011) Helmut Kettenmann et al.   PHYSIOLOGICAL REVIEWS

Asc Modulates the Function of NLRC4 in Response to Infection of Macrophages by Legionella pneumophila

(2011) C. L. Case et al.   mBio

Role of the Nlrp3 Inflammasome in Microbial Infection

(2011) Paras K. Anand et al.   Frontiers in Microbiology

Asc-Dependent and Independent Mechanisms Contribute to Restriction of Legionella Pneumophila Infection in Murine Macrophages

(2011) Dalia H. A. Abdelaziz et al.   Frontiers in Microbiology

Acute Disseminating Encephalomyelitis Following Legionnaires Disease

(2010) Lonneke M. L. de Lau et al.   ARCHIVES OF NEUROLOGY

The Inflammasomes

(2010) Kate Schroder et al.   CELL

Microglia in the CNS: Immigrants from another world

(2010) Marco Prinz et al.   GLIA

Pore Formation Triggered by Legionella spp. Is an Nlrc4 Inflammasome-Dependent Host Cell Response That Precedes Pyroptosis

(2010) T. N. Silveira et al.   INFECTION AND IMMUNITY

Nlrc4/Ipaf/CLAN/CARD12: More than a flagellin sensor

(2010) Dalia H. Abdelaziz et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Involvement of the AIM2, NLRC4, and NLRP3 Inflammasomes in Caspase-1 Activation by Listeria monocytogenes

(2010) Jianghong Wu et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Microglial Physiology: Unique Stimuli, Specialized Responses

(2009) Richard M. Ransohoff et al.   Annual Review of Immunology

Interleukin-18 regulates motor activity, anxiety and spatial learning without affecting synaptic plasticity

(2009) Takahiro Yaguchi et al.   BEHAVIOURAL BRAIN RESEARCH

Modulation of caspases and their non-apoptotic functions byLegionella pneumophila

(2009) Amal O. Amer   CELLULAR MICROBIOLOGY

Asc and Ipaf Inflammasomes Direct Distinct Pathways for Caspase-1 Activation in Response to Legionella pneumophila

(2009) C. L. Case et al.   INFECTION AND IMMUNITY

Microglia in Infectious Diseases of the Central Nervous System

(2009) Monica M. Mariani et al.   Journal of Neuroimmune Pharmacology

Pyroptosis: host cell death and inflammation

(2009) Tessa Bergsbaken et al.   NATURE REVIEWS MICROBIOLOGY

NOD-like receptors (NLRs): bona fide intracellular microbial sensors

(2008) Michael H Shaw et al.   CURRENT OPINION IN IMMUNOLOGY

NOD2 plays an important role in the inflammatory responses of microglia and astrocytes to bacterial CNS pathogens

(2008) Vinita S. Chauhan et al.   GLIA

In vivo effect of adhesion inhibitor heparin on Legionella pneumophila pathogenesis in a murine pneumonia model

(2008) Florence Ader et al.   INTENSIVE CARE MEDICINE

Amyloid-β oligomers set fire to inflammasomes and induce Alzheimer's pathology

(2008) Antero Salminen et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Japanese Encephalitis Virus infection induces IL-18 and IL-1β in microglia and astrocytes: Correlation with in vitro cytokine responsiveness of glial cells and subsequent neuronal death

(2008) Sulagna Das et al.   JOURNAL OF NEUROIMMUNOLOGY

The NALP3 inflammasome is involved in the innate immune response to amyloid-β

(2008) Annett Halle et al.   NATURE IMMUNOLOGY

From bone marrow to microglia: barriers and avenues

(2008) Nathalie Davoust et al.   TRENDS IN IMMUNOLOGY

Interleukin-18 produced by peripheral blood cells is increased in Alzheimer’s disease and correlates with cognitive impairment

(2007) Paola Bossù et al.   BRAIN BEHAVIOR AND IMMUNITY

Degradation of fibrillar forms of Alzheimer's amyloid β-peptide by macrophages

(2007) Amitabha Majumdar et al.   NEUROBIOLOGY OF AGING