Astrocyte immune responses in epilepsy

Enhanced Epidermal Growth Factor, Hepatocyte Growth Factor, and Vascular Endothelial Growth Factor Expression in Tuberous Sclerosis Complex

(2011) Whitney E. Parker et al.   AMERICAN JOURNAL OF PATHOLOGY

Activation of toll-like receptor, RAGE and HMGB1 signalling in malformations of cortical development

(2011) E. Zurolo et al.   BRAIN

IL-1 receptor/Toll-like receptor signaling in infection, inflammation, stress and neurodegeneration couples hyperexcitability and seizures

(2011) Annamaria Vezzani et al.   BRAIN BEHAVIOR AND IMMUNITY

Expression of monocyte chemoattractant protein-1 in brain tissue of patients with intractable epilepsy

(2011) Y. Wu et al.   CLINICAL NEUROPATHOLOGY

Upregulation of adenosine kinase in astrocytes in experimental and human temporal lobe epilepsy

(2011) Eleonora Aronica et al.   EPILEPSIA

Molecular cascades that mediate the influence of inflammation on epilepsy

(2011) Alon Friedman et al.   EPILEPSIA

Inflammation in epilepsy: Clinical observations

(2011) Eleonora Aronica et al.   EPILEPSIA

Epilepsy and brain inflammation

(2011) Annamaria Vezzani et al.   EXPERIMENTAL NEUROLOGY

A trio of microRNAs that control Toll-like receptor signalling

(2011) S. R. Quinn et al.   INTERNATIONAL IMMUNOLOGY

Interleukin-1 type 1 receptor/Toll-like receptor signalling in epilepsy: the importance of IL-1beta and high-mobility group box 1

(2011) M. Maroso et al.   JOURNAL OF INTERNAL MEDICINE

Epileptiform Activity Induces Vascular Remodeling and Zonula Occludens 1 Downregulation in Organotypic Hippocampal Cultures: Role of VEGF Signaling Pathways

(2011) M. Morin-Brureau et al.   JOURNAL OF NEUROSCIENCE

Crosstalk in NF-κB signaling pathways

(2011) Andrea Oeckinghaus et al.   NATURE IMMUNOLOGY

MHCI negatively regulates synapse density during the establishment of cortical connections

(2011) Marian W Glynn et al.   NATURE NEUROSCIENCE

IL-1β is induced in reactive astrocytes in the somatosensory cortex of rats with genetic absence epilepsy at the onset of spike-and-wave discharges, and contributes to their occurrence

(2011) Demet Akin et al.   NEUROBIOLOGY OF DISEASE

Inflammation and prevention of epileptogenesis

(2011) Teresa Ravizza et al.   NEUROSCIENCE LETTERS

Neuroglial interactions mediated by purinergic signalling in the pathophysiology of CNS disorders

(2011) Carlos Matute et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Adenosine receptors and brain diseases: Neuroprotection and neurodegeneration

(2010) Catarina V. Gomes et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

A conceptual revolution in the relationships between the brain and immunity

(2010) Michal Schwartz et al.   BRAIN BEHAVIOR AND IMMUNITY

Tuberous sclerosis: A primary pathology of astrocytes?

(2010) Alexander A. Sosunov et al.   EPILEPSIA

Glia as a source of cytokines: Implications for neuronal excitability and survival

(2010) Annamaria Vezzani et al.   EPILEPSIA

The clinicopathologic spectrum of focal cortical dysplasias: A consensus classification proposed by an ad hoc Task Force of the ILAE Diagnostic Methods Commission1

(2010) Ingmar Blümcke et al.   EPILEPSIA

Expression pattern of miR-146a, an inflammation-associated microRNA, in experimental and human temporal lobe epilepsy

(2010) E. Aronica et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Inflammation in neurodegenerative diseases

(2010) Sandra Amor et al.   IMMUNOLOGY

Differential Regulation of Interleukin-1 Receptor-associated Kinase-1 (IRAK-1) and IRAK-2 by MicroRNA-146a and NF-κB in Stressed Human Astroglial Cells and in Alzheimer Disease

(2010) Jian Guo Cui et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

New Perspectives in MicroRNA Regulation of Innate Immunity

(2010) Michael P. Gantier   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Toll-like receptor 4 and high-mobility group box-1 are involved in ictogenesis and can be targeted to reduce seizures

(2010) Mattia Maroso et al.   NATURE MEDICINE

The role of inflammation in epilepsy

(2010) Annamaria Vezzani et al.   Nature Reviews Neurology

Tissue plasminogen activator and urokinase plasminogen activator in human epileptogenic pathologies

(2010) A.M. Iyer et al.   NEUROSCIENCE

Crosstalk pathways between Toll-like receptors and the complement system

(2010) George Hajishengallis et al.   TRENDS IN IMMUNOLOGY

Astrocytes: biology and pathology

(2009) Michael V. Sofroniew et al.   ACTA NEUROPATHOLOGICA

The tuberous sclerosis complex

(2009) Ksenia A. Orlova et al.   Annals of the New York Academy of Sciences

The cortical innate immune response increases local neuronal excitability leading to seizures

(2009) K. M. Rodgers et al.   BRAIN

Gene Expression Analysis of Tuberous Sclerosis Complex Cortical Tubers Reveals Increased Expression of Adhesion and Inflammatory Factors

(2009) Karin Boer et al.   BRAIN PATHOLOGY

Astrocyte dysfunction in epilepsy

(2009) Gerald Seifert et al.   BRAIN RESEARCH REVIEWS

Effects of SC58236, a selective COX-2 inhibitor, on epileptogenesis and spontaneous seizures in a rat model for temporal lobe epilepsy

(2009) L. Holtman et al.   EPILEPSY RESEARCH

Blood–brain barrier breakdown-inducing astrocytic transformation: Novel targets for the prevention of epilepsy

(2009) Alon Friedman et al.   EPILEPSY RESEARCH

Contributions of peripheral inflammation to seizure susceptibility: Cytokines and brain excitability

(2009) Kiarash Riazi et al.   EPILEPSY RESEARCH

Inflammation and Anti-Inflammatory Strategies for Alzheimer’s Disease – A Mini-Review

(2009) Benjamin Brian Alexander McNaull et al.   GERONTOLOGY

The interleukin-1 receptor/Toll-like receptor superfamily: 10 years of progress

(2009) Luke A. J. O'Neill   IMMUNOLOGICAL REVIEWS

Complement Factor H, a Marker of Self Protects against Experimental Autoimmune Encephalomyelitis

(2009) M. R. Griffiths et al.   JOURNAL OF IMMUNOLOGY

The spectrum of phenotypes caused by variants in the CFH gene

(2009) Camiel J.F. Boon et al.   MOLECULAR IMMUNOLOGY

Viral-like brain inflammation during development causes increased seizure susceptibility in adult rats

(2009) M.A. Galic et al.   NEUROBIOLOGY OF DISEASE

COX-2 inhibition controls P-glycoprotein expression and promotes brain delivery of phenytoin in chronic epileptic rats

(2009) Erwin A. van Vliet et al.   NEUROPHARMACOLOGY

Increase of intracellular Ca2+ by P2X and P2Y receptor-subtypes in cultured cortical astroglia of the rat

(2009) W. Fischer et al.   NEUROSCIENCE

IMMUNOLOGY: Dangers In and Out

(2009) M. E. Bianchi et al.   SCIENCE

Cellular distribution of vascular endothelial growth factor A (VEGFA) and B (VEGFB) and VEGF receptors 1 and 2 in focal cortical dysplasia type IIB

(2008) Karin Boer et al.   ACTA NEUROPATHOLOGICA

Adding fuel to fire: microRNAs as a new class of mediators of inflammation

(2008) F J Sheedy et al.   ANNALS OF THE RHEUMATIC DISEASES

The role of cytokines in the pathophysiology of epilepsy

(2008) Annamaria Vezzani et al.   BRAIN BEHAVIOR AND IMMUNITY

Neonatal inflammation produces selective behavioural deficits and alters N-methyl-d-aspartate receptor subunit mRNA in the adult rat brain

(2008) E.-M. Harré et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Interleukin Converting Enzyme inhibition impairs kindling epileptogenesis in rats by blocking astrocytic IL-1β production

(2008) Teresa Ravizza et al.   NEUROBIOLOGY OF DISEASE

Metabotropic Glutamate Receptors in Glial Cells

(2008) Simona D’Antoni et al.   NEUROCHEMICAL RESEARCH

Astrocytes in the Epileptic Brain

(2008) Jonathon Wetherington et al.   NEURON

Metabotropic glutamate receptors as targets for multipotential treatment of neurological disorders

(2008) Kimberly R. Byrnes et al.   Neurotherapeutics

MicroRNAs and immunity: Novel players in the regulation of normal immune function and inflammation

(2008) Enikö Sonkoly et al.   SEMINARS IN CANCER BIOLOGY

Mechanisms of Epileptogenesis in Tuberous Sclerosis Complex and Related Malformations of Cortical Development with Abnormal Glioneuronal Proliferation

(2007) Michael Wong   EPILEPSIA

Seizure-Induced Up-Regulation of P-Glycoprotein at the Blood-Brain Barrier through Glutamate and Cyclooxygenase-2 Signaling

(2007) B. Bauer et al.   MOLECULAR PHARMACOLOGY

Innate and adaptive immunity during epileptogenesis and spontaneous seizures: Evidence from experimental models and human temporal lobe epilepsy

(2007) Teresa Ravizza et al.   NEUROBIOLOGY OF DISEASE

Gene expression profile analysis of epilepsy-associated gangliogliomas

(2007) E. Aronica et al.   NEUROSCIENCE