Glycoprotein Hormones and Their Receptors Emerged at the Origin of Metazoans

The Evolution of the GPCR Signaling System in Eukaryotes: Modularity, Conservation, and the Transition to Metazoan Multicellularity

(2014) Alex de Mendoza et al.   Genome Biology and Evolution

The Analysis of Eight Transcriptomes from All Poriferan Classes Reveals Surprising Genetic Complexity in Sponges

(2014) Ana Riesgo et al.   MOLECULAR BIOLOGY AND EVOLUTION

Multi-functional norrin is a ligand for the LGR4 receptor

(2013) C. Deng et al.   JOURNAL OF CELL SCIENCE

MAFFT Multiple Sequence Alignment Software Version 7: Improvements in Performance and Usability

(2013) K. Katoh et al.   MOLECULAR BIOLOGY AND EVOLUTION

The Genome of the Ctenophore Mnemiopsis leidyi and Its Implications for Cell Type Evolution

(2013) J. F. Ryan et al.   SCIENCE

PhyloBayes MPI: Phylogenetic Reconstruction with Infinite Mixtures of Profiles in a Parallel Environment

(2013) Nicolas Lartillot et al.   SYSTEMATIC BIOLOGY

The Capsaspora genome reveals a complex unicellular prehistory of animals

(2013) Hiroshi Suga et al.   Nature Communications

CCN proteins: A centralized communication network

(2013) Bernard Perbal   Journal of Cell Communication and Signaling

Distinct Expression Patterns of Glycoprotein Hormone Subunits in the LophotrochozoanAplysia: Implications for the Evolution of Neuroendocrine Systems in Animals

(2012) Andreas Heyland et al.   ENDOCRINOLOGY

Identification, expression of a glycoprotein hormone receptor homolog in the amphioxus Branchiostoma belcheri with implications for origin of vertebrate GpHRs

(2012) Juan Dong et al.   GENERAL AND COMPARATIVE ENDOCRINOLOGY

Extensive conservation of ancient microsynteny across metazoans due to cis-regulatory constraints

(2012) M. Irimia et al.   GENOME RESEARCH

Insights into bilaterian evolution from three spiralian genomes

(2012) Oleg Simakov et al.   NATURE

The Origin of GPCRs: Identification of Mammalian like Rhodopsin, Adhesion, Glutamate and Frizzled GPCRs in Fungi

(2012) Arunkumar Krishnan et al.   PLoS One

Maternal xNorrin, a Canonical Wnt Signaling Agonist and TGF-β Antagonist, Controls Early Neuroectoderm Specification in Xenopus

(2012) Suhong Xu et al.   PLOS BIOLOGY

Emergence and evolution of the glycoprotein hormone and neurotrophin gene families in vertebrates

(2011) Sandra Santos et al.   BMC EVOLUTIONARY BIOLOGY

An evolutionary comparison of leucine-rich repeat containing G protein-coupled receptors reveals a novel LGR subtype

(2011) Matthias B. Van Hiel et al.   PEPTIDES

Evolution of the TGF-β Signaling Pathway and Its Potential Role in the Ctenophore, Mnemiopsis leidyi

(2011) Kevin Pang et al.   PLoS One

Synthesis and secretion of gonadotropins including structure-function correlates

(2011) George R. Bousfield et al.   REVIEWS IN ENDOCRINE & METABOLIC DISORDERS

Bone morphogenetic protein and growth differentiation factor cytokine families and their protein antagonists

(2010) Christopher C. Rider et al.   BIOCHEMICAL JOURNAL

MSAProbs: multiple sequence alignment based on pair hidden Markov models and partition function posterior probabilities

(2010) Y. Liu et al.   BIOINFORMATICS

BMGE (Block Mapping and Gathering with Entropy): a new software for selection of phylogenetic informative regions from multiple sequence alignments

(2010) Alexis Criscuolo et al.   BMC EVOLUTIONARY BIOLOGY

Evolution of GnRH: Diving deeper

(2010) Graeme J. Roch et al.   GENERAL AND COMPARATIVE ENDOCRINOLOGY

Neuroendocrine cells in Drosophila melanogaster producing GPA2/GPB5, a hormone with homology to LH, FSH and TSH

(2010) Azza Sellami et al.   GENERAL AND COMPARATIVE ENDOCRINOLOGY

The Amphimedon queenslandica genome and the evolution of animal complexity

(2010) Mansi Srivastava et al.   NATURE

Distinct Expression Patterns of Glycoprotein Hormone-α2 and -β5 in a Basal Chordate Suggest Independent Developmental Functions

(2009) Sandra Dos Santos et al.   ENDOCRINOLOGY

Expression of the gene for ancestral glycoprotein hormone β subunit in the nerve cord of amphioxus

(2009) Yukiko Tando et al.   GENERAL AND COMPARATIVE ENDOCRINOLOGY

Thyrostimulin, but Not Thyroid-stimulating Hormone (TSH), Acts as a Paracrine Regulator to Activate the TSH Receptor in Mammalian Ovary

(2009) Su-Chin Sun et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A relaxin-like peptide purified from radial nerves induces oocyte maturation and ovulation in the starfish, Asterina pectinifera

(2009) M. Mita et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Homolog of the Vertebrate Thyrostimulin Glycoprotein Hormone α Subunit (GPA2) is Expressed in Amphioxus Neurons

(2009) Yukiko Tando et al.   ZOOLOGICAL SCIENCE

The amphioxus genome illuminates vertebrate origins and cephalochordate biology

(2008) L. Z. Holland et al.   GENOME RESEARCH

A sea lamprey glycoprotein hormone receptor similar with gnathostome thyrotropin hormone receptor

(2008) Mihael Freamat et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

The amphioxus genome and the evolution of the chordate karyotype

(2008) Nicholas H. Putnam et al.   NATURE

The genome of the choanoflagellate Monosiga brevicollis and the origin of metazoans

(2008) Nicole King et al.   NATURE

A genome-wide inventory of neurohormone GPCRs in the red flour beetle Tribolium castaneum

(2007) Frank Hauser et al.   FRONTIERS IN NEUROENDOCRINOLOGY

Comparative genomics of leucine-rich repeats containing G protein-coupled receptors and their ligands

(2007) Tom Van Loy et al.   GENERAL AND COMPARATIVE ENDOCRINOLOGY