A Genomic Survey of HECT Ubiquitin Ligases in Eukaryotes Reveals Independent Expansions of the HECT System in Several Lineages

The Nedd4-like ubiquitin E3 ligases target angiomotin/p130 to ubiquitin-dependent degradation

(2012) Chenji Wang et al.   BIOCHEMICAL JOURNAL

EDD induces cell cycle arrest by increasing p53 levels

(2012) Veronique A.J. Smits   CELL CYCLE

Genomic Survey of Premetazoans Shows Deep Conservation of Cytoplasmic Tyrosine Kinases and Multiple Radiations of Receptor Tyrosine Kinases

(2012) H. Suga et al.   Science Signaling

Premetazoan Origin of the Hippo Signaling Pathway

(2012) Arnau Sebé-Pedrós et al.   Cell Reports

Hectd1 regulates intracellular trafficking of Hsp90 to control its secretion and cell motility of the cranial mesenchyme

(2011) Anjali Sarkar et al.   DEVELOPMENTAL BIOLOGY

Structure of the HECT:ubiquitin complex and its role in ubiquitin chain elongation

(2011) Elena Maspero et al.   EMBO REPORTS

Regulation of Inducible Nitric-oxide Synthase by the SPRY Domain- and SOCS Box-containing Proteins

(2011) Tadashi Nishiya et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Physical and Functional Interaction of the HECT Ubiquitin-protein Ligases E6AP and HERC2

(2011) Simone Kühnle et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

UBE3C genetic variations as potent markers of nasal polyps in Korean asthma patients

(2011) Charisse Flerida A Pasaje et al.   JOURNAL OF HUMAN GENETICS

Regulation of the Human Papillomavirus Type 18 E6/E6AP Ubiquitin Ligase Complex by the HECT Domain-Containing Protein EDD

(2011) V. Tomaic et al.   JOURNAL OF VIROLOGY

Rooting the Eukaryotic Tree with Mitochondrial and Bacterial Proteins

(2011) R. Derelle et al.   MOLECULAR BIOLOGY AND EVOLUTION

Phylogenetic Relationships within the Opisthokonta Based on Phylogenomic Analyses of Conserved Single-Copy Protein Domains

(2011) G. Torruella et al.   MOLECULAR BIOLOGY AND EVOLUTION

The Pfam protein families database

(2011) M. Punta et al.   NUCLEIC ACIDS RESEARCH

The E3 Ubiquitin Ligase Activity of Trip12 Is Essential for Mouse Embryogenesis

(2011) Masashi Kajiro et al.   PLoS One

Itch E3 ubiquitin ligase regulates large tumor suppressor 1 stability

(2011) K. C. Ho et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The ubiquitin ligase HACE1 regulates Golgi membrane dynamics during the cell cycle

(2011) Danming Tang et al.   Nature Communications

Animal HECT ubiquitin ligases: evolution and functional implications

(2010) Ignacio Marín   BMC EVOLUTIONARY BIOLOGY

HERC2 Is an E3 Ligase That Targets BRCA1 for Degradation

(2010) W. Wu et al.   CANCER RESEARCH

HECT E3 Ubiquitin Ligase Nedd4-1 Ubiquitinates ACK and Regulates Epidermal Growth Factor (EGF)-Induced Degradation of EGF Receptor and ACK

(2010) Q. Lin et al.   MOLECULAR AND CELLULAR BIOLOGY

A HECT E3 ubiquitin ligase negatively regulates Arabidopsis leaf senescence through degradation of the transcription factor WRKY53

(2010) Ying Miao et al.   PLANT JOURNAL

Extending the C2 domain family: C2s in PKCs δ, ϵ,η,θ, phospholipases, GAPs, and perforin

(2010) C.P. Pointing et al.   PROTEIN SCIENCE

Armadillo-repeat protein functions: questions for little creatures

(2010) Rita Tewari et al.   TRENDS IN CELL BIOLOGY

PhyloBayes 3: a Bayesian software package for phylogenetic reconstruction and molecular dating

(2009) Nicolas Lartillot et al.   BIOINFORMATICS

Origin and evolution of ubiquitin-conjugating enzymes from Guillardia theta nucleomorph to hominoid

(2009) Muying Ying et al.   GENE

What Was the Set of Ubiquitin and Ubiquitin-Like Conjugating Enzymes in the Eukaryote Common Ancestor?

(2009) Caroline Michelle et al.   JOURNAL OF MOLECULAR EVOLUTION

Physiological functions of the HECT family of ubiquitin ligases

(2009) Daniela Rotin et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Ubiquitin ligase Rsp5p is involved in the gene expression changes during nutrient limitation inSaccharomyces cerevisiae

(2009) F. Cardona et al.   YEAST

HECTD2 Is Associated with Susceptibility to Mouse and Human Prion Disease

(2009) Sarah E. Lloyd et al.   PLoS Genetics

Targeting Proteins for Destruction by the Ubiquitin System: Implications for Human Pathobiology

(2008) Alan L. Schwartz et al.   Annual Review of Pharmacology and Toxicology

The E3 ubiquitin ligase HECTD3 regulates ubiquitination and degradation of Tara

(2008) Jian Yu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Versatile role of the yeast ubiquitin ligase Rsp5p in intracellular trafficking: Figure 1

(2008) Naima Belgareh-Touzé et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

The RCC1 superfamily: From genes, to function, to disease

(2008) Ouadah Hadjebi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Mechanism of Ubiquitin-Chain Formation by the Human Anaphase-Promoting Complex

(2008) Lingyan Jin et al.   CELL

Interaction Between Syntaxin 8 and HECTd3, a HECT Domain Ligase

(2008) Lisheng Zhang et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

G2E3 Is a Dual Function Ubiquitin Ligase Required for Early Embryonic Development

(2008) William S. Brooks et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Anatomy of the E2 ligase fold: Implications for enzymology and evolution of ubiquitin/Ub-like protein conjugation

(2008) A. Maxwell Burroughs et al.   JOURNAL OF STRUCTURAL BIOLOGY

The genome of the choanoflagellate Monosiga brevicollis and the origin of metazoans

(2008) Nicole King et al.   NATURE

A novel HECT-type E3 ubiquitin protein ligase NEDL1 enhances the p53-mediated apoptotic cell death in its catalytic activity-independent manner

(2008) Y Li et al.   ONCOGENE

Natural history of the E1-like superfamily: Implication for adenylation, sulfur transfer, and ubiquitin conjugation

(2008) A. Maxwell Burroughs et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS