Effects of MTHFR Genetic Polymorphisms on Toxicity and Clinical Response of Irinotecan-Based Chemotherapy in Patients with Colorectal Cancer
Published 2014 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Effects of MTHFR Genetic Polymorphisms on Toxicity and Clinical Response of Irinotecan-Based Chemotherapy in Patients with Colorectal Cancer
Authors
Keywords
-
Journal
Genetic Testing and Molecular Biomarkers
Volume 18, Issue 5, Pages 313-322
Publisher
Mary Ann Liebert Inc
Online
2014-03-10
DOI
10.1089/gtmb.2013.0494
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Therapeutic Targeting of CPT-11 Induced Diarrhea: A Case for Prophylaxis
- (2013) Umang Swami et al. CURRENT DRUG TARGETS
- MTHFR polymorphisms and capecitabine-induced toxicity in patients with metastatic colorectal cancer
- (2013) Lieke H. van Huis-Tanja et al. Pharmacogenetics and Genomics
- Intestinal glucuronidation protects against chemotherapy-induced toxicity by irinotecan (CPT-11)
- (2013) S. Chen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Antifolates in cancer therapy: Structure, activity and mechanisms of drug resistance
- (2012) Nitzan Gonen et al. DRUG RESISTANCE UPDATES
- Association study on MTHFR polymorphisms and meningioma in northern China
- (2012) Ruiyan Li et al. GENE
- Association of Methylentetraydrofolate Reductase (MTHFR) 677 C > T gene polymorphism and homocysteine levels in psoriasis vulgaris patients from Malaysia: a case-control study
- (2012) Siaw C Liew et al. Nutrition Journal
- Pharmacogenetic markers of toxicity for chemotherapy in colorectal cancer patients
- (2012) Lucía Cortejoso et al. PHARMACOGENOMICS
- DNA Repair Gene and MTHFR Gene Polymorphisms as Prognostic Markers in Locally Advanced Adenocarcinoma of the Esophagus or Stomach Treated with Cisplatin and 5-Fluorouracil-Based Neoadjuvant Chemotherapy
- (2011) Katja Ott et al. ANNALS OF SURGICAL ONCOLOGY
- Methylenetetrahydrofolate reductase genetic polymorphisms and toxicity to 5-FU-based chemoradiation in rectal cancer
- (2011) F Thomas et al. BRITISH JOURNAL OF CANCER
- Clinical implications of UGT1A1*28 genotype testing in colorectal cancer patients
- (2011) Katerina Shulman et al. CANCER
- Risk of colorectal cancer associated with the methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism in the Kashmiri population
- (2011) A.S. Sameer et al. GENETICS AND MOLECULAR RESEARCH
- Polymorphisms in folate-related genes: impact on risk of adult acute lymphoblastic leukemia rather than pediatric in Han Chinese
- (2011) Lin Yang et al. LEUKEMIA & LYMPHOMA
- Impact of SHMT1 polymorphism on the clinical outcome of patients with metastatic colorectal cancer treated with first-line FOLFIRI+bevacizumab
- (2011) Barna Budai et al. Pharmacogenetics and Genomics
- Methylenetetrahydrofolate Reductase Polymorphism (677 C>T) Predicts Long Time to Progression in Metastatic Colon Cancer Treated with 5-Fluorouracil and Folinic Acid
- (2010) Omar Castillo-Fernández et al. ARCHIVES OF MEDICAL RESEARCH
- Methylenetetrahydrofolate reductase C677T polymorphism in patients with gastric and colorectal cancer in a Korean population
- (2010) Lian-Hua Cui et al. BMC CANCER
- Oxaliplatin, irinotecan and capecitabine as first-line therapy in metastatic colorectal cancer (mCRC): a dose-finding study and pharmacogenomic analysis
- (2010) R Zarate et al. BRITISH JOURNAL OF CANCER
- Anticancer oral therapy: Emerging related issues
- (2010) Giuseppe Luigi Banna et al. CANCER TREATMENT REVIEWS
- Critical evaluation of the Newcastle-Ottawa scale for the assessment of the quality of nonrandomized studies in meta-analyses
- (2010) Andreas Stang EUROPEAN JOURNAL OF EPIDEMIOLOGY
- Life-threatening methylenetetrahydrofolate reductase (MTHFR) deficiency with extremely early onset: Characterization of two novel mutations in compound heterozygous patients
- (2010) Thierry Forges et al. MOLECULAR GENETICS AND METABOLISM
- Prediction of irinotecan and 5-fluorouracil toxicity and response in patients with advanced colorectal cancer
- (2010) B Glimelius et al. PHARMACOGENOMICS JOURNAL
- Alleviating Cancer Drug Toxicity by Inhibiting a Bacterial Enzyme
- (2010) B. D. Wallace et al. SCIENCE
- Genetic polymorphism of inosine-triphosphate-pyrophosphatase influences mercaptopurine metabolism and toxicity during treatment of acute lymphoblastic leukemia individualized for thiopurine-S-methyl-transferase status
- (2009) Gabriele Stocco et al. Expert Opinion On Drug Safety
- The dual EGFR/HER-2 tyrosine kinase inhibitor lapatinib sensitizes colon and gastric cancer cells to the irinotecan active metabolite SN-38
- (2009) Melissa J. LaBonte et al. INTERNATIONAL JOURNAL OF CANCER
- Association of Molecular Markers With Toxicity Outcomes in a Randomized Trial of Chemotherapy for Advanced Colorectal Cancer: The FOCUS Trial
- (2009) Michael S. Braun et al. JOURNAL OF CLINICAL ONCOLOGY
- Methylenetetrahydrofolate Reductase (MTHFR): A Novel Target for Cancer Therapy
- (2008) J. Stankova et al. CURRENT PHARMACEUTICAL DESIGN
- New response evaluation criteria in solid tumours: Revised RECIST guideline (version 1.1)
- (2008) E.A. Eisenhauer et al. EUROPEAN JOURNAL OF CANCER
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started