Do polyphenols enter the brain and does it matter? Some theoretical and practical considerations

Bioavailability of Gallic Acid and Catechins from Grape Seed Polyphenol Extract is Improved by Repeated Dosing in Rats: Implications for Treatment in Alzheimer's Disease

(2017) Mario G. Ferruzzi et al.   JOURNAL OF ALZHEIMERS DISEASE

Vitamin E Paradox in Alzheimer's Disease: It Does Not Prevent Loss of Cognition and May Even Be Detrimental

(2017) Ana Lloret et al.   JOURNAL OF ALZHEIMERS DISEASE

Ascorbic acid partly antagonizes resveratrol mediated heme oxygenase-1 but not paraoxonase-1 induction in cultured hepatocytes - role of the redox-regulated transcription factor Nrf2

(2013) Anika E Wagner et al.   BMC Complementary and Alternative Medicine

Artefacts in cell culture: α-Ketoglutarate can scavenge hydrogen peroxide generated by ascorbate and epigallocatechin gallate in cell culture media

(2011) Lee Hua Long et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Hormetins, antioxidants and prooxidants: defining quercetin-, caffeic acid- and rosmarinic acid-mediated life extension in C. elegans

(2011) Kerstin Pietsch et al.   BIOGERONTOLOGY

Flavonoid modulation of GABAA receptors

(2011) Jane R. Hanrahan et al.   BRITISH JOURNAL OF PHARMACOLOGY

Polyphenols and Human Health: A Prospectus

(2011) Francesco Visioli et al.   CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION

The Biological Relevance of Direct Antioxidant Effects of Polyphenols for Cardiovascular Health in Humans Is Not Established

(2011) Peter C. H. Hollman et al.   JOURNAL OF NUTRITION

Flavonoids and the CNS

(2011) Anna Jäger et al.   MOLECULES

Normal gut microbiota modulates brain development and behavior

(2011) R. D. Heijtz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Instability of, and generation of hydrogen peroxide by, phenolic compounds in cell culture media

(2010) Lee Hua Long et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Flavonoid binding to human serum albumin

(2010) Alessandro Bolli et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The Ginkgo biloba extract EGb 761® and its main constituent flavonoids and ginkgolides increase extracellular dopamine levels in the rat prefrontal cortex

(2010) T Yoshitake et al.   BRITISH JOURNAL OF PHARMACOLOGY

The regular consumption of a polyphenol-rich apple does not influence endothelial function: a randomised double-blind trial in hypercholesterolemic adults

(2010) S Auclair et al.   EUROPEAN JOURNAL OF CLINICAL NUTRITION

The pharmacological properties of antidepressants

(2010) Giorgio Racagni et al.   INTERNATIONAL CLINICAL PSYCHOPHARMACOLOGY

Docosahexaenoic Acid Supplementation and Cognitive Decline in Alzheimer Disease

(2010) Joseph F. Quinn et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

The Flavanol (−)-Epicatechin Prevents Stroke Damage through the Nrf2/HO1 Pathway

(2010) Zahoor A Shah et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Pharmacokinetics and Tissue Distribution of 14C-Labeled Grape Polyphenols in the Periphery and the Central Nervous System Following Oral Administration

(2010) Elsa M. Janle et al.   JOURNAL OF MEDICINAL FOOD

Dietary inhibitors of monoamine oxidase A

(2010) Sarah E. Dixon Clarke et al.   JOURNAL OF NEURAL TRANSMISSION

Grape Polyphenols Do Not Affect Vascular Function in Healthy Men

(2010) Linda A. J. van Mierlo et al.   JOURNAL OF NUTRITION

Improvement of Endothelial Function With Dietary Flavanols Is Associated With Mobilization of Circulating Angiogenic Cells in Patients With Coronary Artery Disease

(2010) Christian Heiss et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Noninvasive quantification of human brain antioxidant concentrations after an intravenous bolus of vitamin C

(2010) Melissa Terpstra et al.   NMR IN BIOMEDICINE

Metabolic fate of polyphenols in the human superorganism

(2010) J. van Duynhoven et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Artefacts in cell culture: Pyruvate as a scavenger of hydrogen peroxide generated by ascorbate or epigallocatechin gallate in cell culture media

(2009) Lee Hua Long et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Mood and gut feelings

(2009) Paul Forsythe et al.   BRAIN BEHAVIOR AND IMMUNITY

Limited antioxidant effect after consumption of a single dose of tomato sauce by young males, despite a rise in plasma lycopene

(2009) Chung-Yung Jetty Lee et al.   FREE RADICAL RESEARCH

Flavonoids and cognitive function: a review of human randomized controlled trial studies and recommendations for future studies

(2009) Anna L. Macready et al.   Genes and Nutrition

Flavonoids and brain health: multiple effects underpinned by common mechanisms

(2009) Jeremy P. E. Spencer   Genes and Nutrition

Improved Measurement of Drug Exposure in the Brain Using Drug-Specific Correction for Residual Blood

(2009) Markus Fridén et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Black tea consumption dose-dependently improves flow-mediated dilation in healthy males

(2009) Davide Grassi et al.   JOURNAL OF HYPERTENSION

Principles and clinical implications of the brain–gut–enteric microbiota axis

(2009) Sang H. Rhee et al.   Nature Reviews Gastroenterology & Hepatology

Ginkgo biloba extract (EGb761®) influences monoaminergic neurotransmission via inhibition of NE uptake, but not MAO activity after chronic treatment

(2009) Christian J. Fehske et al.   PHARMACOLOGICAL RESEARCH

Effect of dietary quercetin on brain quercetin levels and the expression of antioxidant and Alzheimer's disease relevant genes in mice

(2009) Patricia Huebbe et al.   PHARMACOLOGICAL RESEARCH

Cellular uptake, stability, visualization by ‘Naturstoff reagent A’, and multidrug resistance protein 1 gene-regulatory activity of cyanidin in human keratinocytes

(2009) I.M.A. Ernst et al.   PHARMACOLOGICAL RESEARCH

Characterization of interactions between polyphenolic compounds and human serum proteins by capillary electrophoresis

(2008) Andréa Diniz et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Lack of effect of acute oral ingestion of vitamin C on oxidative stress, arterial stiffness or blood pressure in healthy subjects

(2008) Ronan P. Kelly et al.   FREE RADICAL RESEARCH

Intake of Flavonoid-Rich Wine, Tea, and Chocolate by Elderly Men and Women Is Associated with Better Cognitive Test Performance

(2008) Eha Nurk et al.   JOURNAL OF NUTRITION

An examination of the effects of the antioxidant Pycnogenol® on cognitive performance, serum lipid profile, endocrinological and oxidative stress biomarkers in an elderly population

(2008) J. Ryan et al.   JOURNAL OF PSYCHOPHARMACOLOGY

Chaotic behavior of the coronary circulation

(2008) Jerome Trzeciakowski et al.   MEDICAL & BIOLOGICAL ENGINEERING & COMPUTING

Vascular action of polyphenols

(2008) Dilip Ghosh et al.   MOLECULAR NUTRITION & FOOD RESEARCH

In vitro and ex vivo anti-inflammatory activity of quercetin in healthy volunteers

(2008) Agnes W. Boots et al.   NUTRITION

Liquid chromatography tandem mass spectrometry identification of proanthocyanidins in rat plasma after oral administration of grape seed extract

(2008) Jeevan K. Prasain et al.   PHYTOMEDICINE