Comprehensive analysis of miRNA expression in T-cell subsets of rheumatoid arthritis patients reveals defined signatures of naive and memory Tregs

Phosphorylation of FOXP3 controls regulatory T cell function and is inhibited by TNF-α in rheumatoid arthritis

(2013) Hong Nie et al.   NATURE MEDICINE

Dual Role of miR-21 in CD4+ T-Cells: Activation-Induced miR-21 Supports Survival of Memory T-Cells and Regulates CCR7 Expression in Naive T-Cells

(2013) Katarzyna Smigielska-Czepiel et al.   PLoS One

Upregulation of miR-24 is associated with a decreased DNA damage response upon etoposide treatment in highly differentiated CD8+ T cells sensitizing them to apoptotic cell death

(2012) Stefan Brunner et al.   AGING CELL

miR-155 is differentially expressed in Treg subsets, which may explain expression level differences of miR-155 in HIV-1 infected patients

(2012) N. Seddiki et al.   BLOOD

miR-146acontrols the resolution of T cell responses in mice

(2012) Lili Yang et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Neuropilin-1 distinguishes natural and inducible regulatory T cells among regulatory T cell subsets in vivo

(2012) Mahesh Yadav et al.   JOURNAL OF EXPERIMENTAL MEDICINE

miR-451 Regulates Dendritic Cell Cytokine Responses to Influenza Infection

(2012) C. M. Rosenberger et al.   JOURNAL OF IMMUNOLOGY

T cells out of control—impaired immune regulation in the inflamed joint

(2012) Ellen J. Wehrens et al.   Nature Reviews Rheumatology

Identification of novel microRNA signatures linked to human lupus disease activity and pathogenesis: miR-21 regulates aberrant T cell responses through regulation of PDCD4 expression

(2011) E. Stagakis et al.   ANNALS OF THE RHEUMATIC DISEASES

Human FoxP3+ regulatory T cells in systemic autoimmune diseases

(2011) Makoto Miyara et al.   AUTOIMMUNITY REVIEWS

miR-146ais a significant brake on autoimmunity, myeloproliferation, and cancer in mice

(2011) Mark P. Boldin et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Distinct microRNA signatures in human lymphocyte subsets and enforcement of the naive state in CD4+ T cells by the microRNA miR-125b

(2011) Riccardo L Rossi et al.   NATURE IMMUNOLOGY

NF- B dysregulation in microRNA-146a-deficient mice drives the development of myeloid malignancies

(2011) J. L. Zhao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Function of miR-146a in Controlling Treg Cell-Mediated Regulation of Th1 Responses

(2010) Li-Fan Lu et al.   CELL

Correlation of a multi-cytokine panel with clinical disease activity in patients with rheumatoid arthritis

(2010) Nataliya Milman et al.   CLINICAL BIOCHEMISTRY

TNF Activates a NF- B-Regulated Cellular Program in Human CD45RA- Regulatory T Cells that Modulates Their Suppressive Function

(2010) M. Nagar et al.   JOURNAL OF IMMUNOLOGY

MicroRNA-21 and MicroRNA-148a Contribute to DNA Hypomethylation in Lupus CD4+ T Cells by Directly and Indirectly Targeting DNA Methyltransferase 1

(2010) W. Pan et al.   JOURNAL OF IMMUNOLOGY

The yin and yang of regulatory T cells and inflammation in RA

(2010) Clare A. Notley et al.   Nature Reviews Rheumatology

Altered microRNA expression profile with miR-146a upregulation in CD4+ T cells from patients with rheumatoid arthritis

(2010) Jingyi Li et al.   ARTHRITIS RESEARCH & THERAPY

An emerging player in the adaptive immune response: microRNA-146a is a modulator of IL-2 expression and activation-induced cell death in T lymphocytes

(2009) G. Curtale et al.   BLOOD

MicroRNAs: Target Recognition and Regulatory Functions

(2009) David P. Bartel   CELL

microRNA-342, microRNA-191 and microRNA-510 are differentially expressed in T regulatory cells of type 1 diabetic patients

(2009) Renata Hezova et al.   CELLULAR IMMUNOLOGY

Human natural Treg microRNA signature: Role of microRNA‐31 and microRNA‐21 in FOXP3 expression

(2009) Redouane Rouas et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

miR-223 is overexpressed in T-lymphocytes of patients affected by rheumatoid arthritis

(2009) Valerio Fulci et al.   HUMAN IMMUNOLOGY

Foxp3-Dependent MicroRNA155 Confers Competitive Fitness to Regulatory T Cells by Targeting SOCS1 Protein

(2009) Li-Fan Lu et al.   IMMUNITY

Functional Delineation and Differentiation Dynamics of Human CD4+ T Cells Expressing the FoxP3 Transcription Factor

(2009) Makoto Miyara et al.   IMMUNITY

MicroRNA miR-326 regulates TH-17 differentiation and is associated with the pathogenesis of multiple sclerosis

(2009) Changsheng Du et al.   NATURE IMMUNOLOGY

MicroRNA-330 acts as tumor suppressor and induces apoptosis of prostate cancer cells through E2F1-mediated suppression of Akt phosphorylation

(2009) K-H Lee et al.   ONCOGENE

Altered T-cell subtypes in spondyloarthritis, rheumatoid arthritis and polymyalgia rheumatica

(2009) Christian Dejaco et al.   RHEUMATOLOGY INTERNATIONAL

Developments in the scientific understanding of rheumatoid arthritis

(2009) Jörg J Goronzy et al.   ARTHRITIS RESEARCH & THERAPY

FOXP3 expression in blood, synovial fluid and synovial tissue during inflammatory arthritis and intra-articular corticosteroid treatment

(2008) S Raghavan et al.   ANNALS OF THE RHEUMATIC DISEASES

Altered expression of MicroRNA in synovial fibroblasts and synovial tissue in rheumatoid arthritis

(2008) Joanna Stanczyk et al.   ARTHRITIS AND RHEUMATISM

Dicer-dependent microRNA pathway safeguards regulatory T cell function

(2008) Adrian Liston et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Selective miRNA disruption in T reg cells leads to uncontrolled autoimmunity

(2008) Xuyu Zhou et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Regulation of progenitor cell proliferation and granulocyte function by microRNA-223

(2008) Jonathan B. Johnnidis et al.   NATURE

Defects in CTLA-4 are associated with abnormal regulatory T cell function in rheumatoid arthritis

(2008) F. Flores-Borja et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MicroRNA miR-21 overexpression in human breast cancer is associated with advanced clinical stage, lymph node metastasis and patient poor prognosis

(2008) L.-X. Yan et al.   RNA

Biomarkers in osteoarthritis

(2008) Frances MK Williams et al.   ARTHRITIS RESEARCH & THERAPY