Prolonged expression of an anti-HIV-1 gp120 minibody to the female rhesus macaque lower genital tract by AAV gene transfer

Protein-Based HIV-1 Microbicides

(2014) Barna Dey et al.   CURRENT HIV RESEARCH

Vectored immunoprophylaxis protects humanized mice from mucosal HIV transmission

(2014) Alejandro B Balazs et al.   NATURE MEDICINE

Homeostatic properties of Lactobacillus jensenii engineered as a live vaginal anti-HIV microbicide

(2013) Hidemi S Yamamoto et al.   BMC MICROBIOLOGY

HIV-1 Infection of Female Genital Tract Tissue for Use in Prevention Studies

(2013) Charlene S. Dezzutti et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

Defining the Interaction of HIV-1 with the Mucosal Barriers of the Female Reproductive Tract

(2013) A. M. Carias et al.   JOURNAL OF VIROLOGY

Durable Knockdown and Protection From HIV Transmission in Humanized Mice Treated With Gel-formulated CD4 Aptamer-siRNA Chimeras

(2013) Lee Adam Wheeler et al.   MOLECULAR THERAPY

Bispecific antibodies directed to CD4 domain 2 and HIV envelope exhibit exceptional breadth and picomolar potency against HIV-1

(2013) C. S. Pace et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Adeno-associated virus (AAV) vectors in gene therapy: immune challenges and strategies to circumvent them

(2013) Sangeetha Hareendran et al.   REVIEWS IN MEDICAL VIROLOGY

Overcoming Preexisting Humoral Immunity to AAV Using Capsid Decoys

(2013) F. Mingozzi et al.   Science Translational Medicine

Intranasal Antibody Gene Transfer in Mice and Ferrets Elicits Broad Protection Against Pandemic Influenza

(2013) M. P. Limberis et al.   Science Translational Medicine

Pre-existing Anti–Adeno-Associated Virus Antibodies as a Challenge in AAV Gene Therapy

(2013) Vedell Louis Jeune et al.   Human Gene Therapy Methods

Inhibitory effect of HIV-specific neutralizing IgA on mucosal transmission of HIV in humanized mice

(2012) E. M. Hur et al.   BLOOD

Distinct transduction difference between adeno-associated virus type 1 and type 6 vectors in human polarized airway epithelia

(2012) Z Yan et al.   GENE THERAPY

Zinc-finger nuclease-mediated gene correction using single AAV vector transduction and enhancement by Food and Drug Administration-approved drugs

(2012) B L Ellis et al.   GENE THERAPY

Directed evolution of novel adeno-associated viruses for therapeutic gene delivery

(2012) M A Bartel et al.   GENE THERAPY

Presence of DNA of adeno-associated virus in subfertile couples, but no association with fertility factors

(2012) J. R. Schlehofer et al.   HUMAN REPRODUCTION

Human cervicovaginal mucus contains an activity that hinders HIV-1 movement

(2012) S A Shukair et al.   Mucosal Immunology

HIV therapy by a combination of broadly neutralizing antibodies in humanized mice

(2012) Florian Klein et al.   NATURE

Topical gel formulation of broadly neutralizing anti-HIV-1 monoclonal antibody VRC01 confers protection against HIV-1 vaginal challenge in a humanized mouse model

(2012) Milena Veselinovic et al.   VIROLOGY

The promise of pre-exposure prophylaxis with antiretroviral drugs to prevent HIV transmission

(2012) Catherine A. Hankins et al.   Current Opinion in HIV and AIDS

MiniCD4 Microbicide Prevents HIV Infection of Human Mucosal Explants and Vaginal Transmission of SHIV162P3 in Cynomolgus Macaques

(2012) Nathalie Dereuddre-Bosquet et al.   PLoS Pathogens

In Vivo Longitudinal Imaging of Experimental Human Papillomavirus Infection in Mice with a Multicolor Fluorescence Mini-Endoscopy System

(2011) M. Mitsunaga et al.   Cancer Prevention Research

Targeting the Vaginal Mucosa with Human Papillomavirus Pseudovirion Vaccines Delivering Simian Immunodeficiency Virus DNA

(2011) S. N. Gordon et al.   JOURNAL OF IMMUNOLOGY

A 10 Patient Case Report on the Impact of Plasmapheresis Upon Neutralizing Factors Against Adeno-associated Virus (AAV) Types 1, 2, 6, and 8

(2011) Virginie Monteilhet et al.   MOLECULAR THERAPY

An Evolved Adeno-associated Viral Variant Enhances Gene Delivery and Gene Targeting in Neural Stem Cells

(2011) Jae-Hyung Jang et al.   MOLECULAR THERAPY

Directed Evolution of Adeno-associated Virus for Enhanced Gene Delivery and Gene Targeting in Human Pluripotent Stem Cells

(2011) Prashanth Asuri et al.   MOLECULAR THERAPY

Antibody-based protection against HIV infection by vectored immunoprophylaxis

(2011) Alejandro B. Balazs et al.   NATURE

Broad neutralization coverage of HIV by multiple highly potent antibodies

(2011) Laura M. Walker et al.   NATURE

Anti-gp120 Minibody Gene Transfer to Female Genital Epithelial Cells Protects against HIV-1 Virus Challenge In Vitro

(2011) Ussama M. Abdel-Motal et al.   PLoS One

Transduction of Human Adipose-Derived Mesenchymal Stem Cells by Recombinant Adeno-Associated Virus Vectors

(2011) Michelle Locke et al.   TISSUE ENGINEERING PART C-METHODS

HIV Infection in the Female Genital Tract: Discrete Influence of the Local Mucosal Microenvironment

(2010) Charu Kaushic et al.   AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY

Early Events in Sexual Transmission of HIV and SIV and Opportunities for Interventions

(2010) Ashley T. Haase   Annual Review of Medicine

Identification of Novel Human Immunodeficiency Virus Type 1-Inhibitory Peptides Based on the Antimicrobial Peptide Database

(2010) G. Wang et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Apples and oranges? Interpreting success in HIV prevention trials

(2010) Lori L. Heise et al.   CONTRACEPTION

High-Efficiency Transduction of Fibroblasts and Mesenchymal Stem Cells by Tyrosine-Mutant AAV2 Vectors for Their Potential Use in Cellular Therapy

(2010) Mengxin Li et al.   HUMAN GENE THERAPY

Enhanced Long-Term Transduction and Multilineage Engraftment of Human Hematopoietic Stem Cells Transduced with Tyrosine-Modified Recombinant Adeno-Associated Virus Serotype 2

(2010) M. Ariel Kauss et al.   HUMAN GENE THERAPY

Prevalence of Serum IgG and Neutralizing Factors Against Adeno-Associated Virus (AAV) Types 1, 2, 5, 6, 8, and 9 in the Healthy Population: Implications for Gene Therapy Using AAV Vectors

(2010) Sylvie Boutin et al.   HUMAN GENE THERAPY

PRO2000 vaginal gel for prevention of HIV-1 infection (Microbicides Development Programme 301): a phase 3, randomised, double-blind, parallel-group trial

(2010) Sheena McCormack et al.   LANCET

Anti-HIV Activity in Cervical-Vaginal Secretions from HIV-Positive and -Negative Women Correlate with Innate Antimicrobial Levels and IgG Antibodies

(2010) Mimi Ghosh et al.   PLoS One

Effectiveness and Safety of Tenofovir Gel, an Antiretroviral Microbicide, for the Prevention of HIV Infection in Women

(2010) Q. Abdool Karim et al.   SCIENCE

Pseudotyped recombinant adeno-associated viral vectors mediate efficient gene transfer into primary human CD34+ peripheral blood progenitor cells

(2009) Marlon R. Veldwijk et al.   CYTOTHERAPY

The TLR9-MyD88 pathway is critical for adaptive immune responses to adeno-associated virus gene therapy vectors in mice

(2009) Jiangao Zhu et al.   JOURNAL OF CLINICAL INVESTIGATION

Worldwide Epidemiology of Neutralizing Antibodies to Adeno‐Associated Viruses

(2009) Roberto Calcedo et al.   JOURNAL OF INFECTIOUS DISEASES

Vector-mediated gene transfer engenders long-lived neutralizing activity and protection against SIV infection in monkeys

(2009) Philip R Johnson et al.   NATURE MEDICINE

Effective, low-titer antibody protection against low-dose repeated mucosal SHIV challenge in macaques

(2009) Ann J Hessell et al.   NATURE MEDICINE

Sustained transgene expression despite T lymphocyte responses in a clinical trial of rAAV1-AAT gene therapy

(2009) M. L. Brantly et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

HIV infection of the genital mucosa in women

(2009) Florian Hladik et al.   Current HIV/AIDS Reports

Intramuscular Administration of AAV1-Lipoprotein Lipase S447X Lowers Triglycerides in Lipoprotein Lipase–Deficient Patients

(2008) Erik S. Stroes et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Efficacy of Carraguard for prevention of HIV infection in women in South Africa: a randomised, double-blind, placebo-controlled trial

(2008) Stephanie Skoler-Karpoff et al.   LANCET

Recombinant Adeno-associated Virus Transduction and Integration

(2008) Brian R Schultz et al.   MOLECULAR THERAPY

Lack of Effectiveness of Cellulose Sulfate Gel for the Prevention of Vaginal HIV Transmission

(2008) Lut Van Damme et al.   NEW ENGLAND JOURNAL OF MEDICINE

SAVVY Vaginal Gel (C31G) for Prevention of HIV Infection: A Randomized Controlled Trial in Nigeria

(2008) Paul J. Feldblum et al.   PLoS One

Effectiveness of Cellulose Sulfate Vaginal Gel for the Prevention of HIV Infection: Results of a Phase III Trial in Nigeria

(2008) Vera Halpern et al.   PLoS One