Bispecific antibodies directed to CD4 domain 2 and HIV envelope exhibit exceptional breadth and picomolar potency against HIV-1
Published 2013 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Bispecific antibodies directed to CD4 domain 2 and HIV envelope exhibit exceptional breadth and picomolar potency against HIV-1
Authors
Keywords
-
Journal
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Volume 110, Issue 33, Pages 13540-13545
Publisher
Proceedings of the National Academy of Sciences
Online
2013-07-23
DOI
10.1073/pnas.1304985110
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Unraveling the divergent results of pre-exposure prophylaxis trials for HIV prevention
- (2012) Ariane van der Straten et al. AIDS
- Broad and potent neutralization of HIV-1 by a gp41-specific human antibody
- (2012) Jinghe Huang et al. NATURE
- HIV therapy by a combination of broadly neutralizing antibodies in humanized mice
- (2012) Florian Klein et al. NATURE
- Subunit organization of the membrane-bound HIV-1 envelope glycoprotein trimer
- (2012) Youdong Mao et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Attitudes and Acceptance of Oral and Parenteral HIV Preexposure Prophylaxis among Potential User Groups: A Multinational Study
- (2012) Andreas B. Eisingerich et al. PLoS One
- The efficacy of an anti-CD4 monoclonal antibody for HIV-1 treatment
- (2011) W. Jeffrey Fessel et al. ANTIVIRAL RESEARCH
- Tenofovir-based pre-exposure prophylaxis for HIV prevention
- (2011) Connie Celum et al. CURRENT OPINION IN INFECTIOUS DISEASES
- Analysis of a Clonal Lineage of HIV-1 Envelope V2/V3 Conformational Epitope-Specific Broadly Neutralizing Antibodies and Their Inferred Unmutated Common Ancestors
- (2011) M. Bonsignori et al. JOURNAL OF VIROLOGY
- Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9
- (2011) Jason S. McLellan et al. NATURE
- Broad neutralization coverage of HIV by multiple highly potent antibodies
- (2011) Laura M. Walker et al. NATURE
- Prevention of HIV-1 Infection with Early Antiretroviral Therapy
- (2011) Myron S. Cohen et al. NEW ENGLAND JOURNAL OF MEDICINE
- Focused Evolution of HIV-1 Neutralizing Antibodies Revealed by Structures and Deep Sequencing
- (2011) X. Wu et al. SCIENCE
- Increasing the Potency and Breadth of an HIV Antibody by Using Structure-Based Rational Design
- (2011) R. Diskin et al. SCIENCE
- Sequence and Structural Convergence of Broad and Potent HIV Antibodies That Mimic CD4 Binding
- (2011) J. F. Scheid et al. SCIENCE
- A Potent and Broad Neutralizing Antibody Recognizes and Penetrates the HIV Glycan Shield
- (2011) R. Pejchal et al. SCIENCE
- Phase 2a Study of the CCR5 Monoclonal Antibody PRO 140 Administered Intravenously to HIV-Infected Adults
- (2010) J. M. Jacobson et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Epitope Mapping of Ibalizumab, a Humanized Anti-CD4 Monoclonal Antibody with Anti-HIV-1 Activity in Infected Patients
- (2010) R. Song et al. JOURNAL OF VIROLOGY
- Variable Loop Glycan Dependency of the Broad and Potent HIV-1-Neutralizing Antibodies PG9 and PG16
- (2010) Katie J. Doores et al. JOURNAL OF VIROLOGY
- Preexposure Chemoprophylaxis for HIV Prevention in Men Who Have Sex with Men
- (2010) Robert M. Grant et al. NEW ENGLAND JOURNAL OF MEDICINE
- A Boost for HIV Vaccine Design
- (2010) D. R. Burton et al. SCIENCE
- Structural Basis for Broad and Potent Neutralization of HIV-1 by Antibody VRC01
- (2010) T. Zhou et al. SCIENCE
- Effectiveness and Safety of Tenofovir Gel, an Antiretroviral Microbicide, for the Prevention of HIV Infection in Women
- (2010) Q. Abdool Karim et al. SCIENCE
- Rational Design of Envelope Identifies Broadly Neutralizing Human Monoclonal Antibodies to HIV-1
- (2010) X. Wu et al. SCIENCE
- Crystal Structure of HIV-1 Primary Receptor CD4 in Complex with a Potent Antiviral Antibody
- (2010) Michael M. Freeman et al. STRUCTURE
- Replication competent molecular clones of HIV-1 expressing Renilla luciferase facilitate the analysis of antibody inhibition in PBMC
- (2010) Tara G. Edmonds et al. VIROLOGY
- Tiered Categorization of a Diverse Panel of HIV-1 Env Pseudoviruses for Assessment of Neutralizing Antibodies
- (2009) M. S. Seaman et al. JOURNAL OF VIROLOGY
- Broadly Neutralizing Monoclonal Antibodies 2F5 and 4E10 Directed against the Human Immunodeficiency Virus Type 1 gp41 Membrane-Proximal External Region Protect against Mucosal Challenge by Simian-Human Immunodeficiency Virus SHIVBa-L
- (2009) A. J. Hessell et al. JOURNAL OF VIROLOGY
- Broad diversity of neutralizing antibodies isolated from memory B cells in HIV-infected individuals
- (2009) Johannes F. Scheid et al. NATURE
- Effective, low-titer antibody protection against low-dose repeated mucosal SHIV challenge in macaques
- (2009) Ann J Hessell et al. NATURE MEDICINE
- Broad and Potent Neutralizing Antibodies from an African Donor Reveal a New HIV-1 Vaccine Target
- (2009) L. M. Walker et al. SCIENCE
- Safety, Pharmacokinetics, and Antiretroviral Activity of Multiple Doses of Ibalizumab (formerly TNX-355), an Anti-CD4 Monoclonal Antibody, in Human Immunodeficiency Virus Type 1-Infected Adults
- (2008) J. M. Jacobson et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Molecular architecture of native HIV-1 gp120 trimers
- (2008) Jun Liu et al. NATURE
- Tumor Regression in Cancer Patients by Very Low Doses of a T Cell-Engaging Antibody
- (2008) R. Bargou et al. SCIENCE
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now