Improved axonal regeneration of transected spinal cord mediated by multichannel collagen conduits functionalized with neurotrophin-3 gene

GDNF Gene Delivery via a 2-(Dimethylamino)ethyl Methacrylate Based Cyclized Knot Polymer for Neuronal Cell Applications

(2013) B. Newland et al.   ACS Chemical Neuroscience

Biomaterial approaches to gene therapies for neurodegenerative disorders of the CNS

(2013) Ben Newland et al.   Biomaterials Science

The effect of intraluminal contact mediated guidance signals on axonal mismatch during peripheral nerve repair

(2012) William T. Daly et al.   BIOMATERIALS

The neurotoxicity of gene vectors and its amelioration by packaging with collagen hollow spheres

(2012) Ben Newland et al.   BIOMATERIALS

Injectable hydrogel materials for spinal cord regeneration: a review

(2012) D Macaya et al.   Biomedical Materials

The Effect of Collagen Nerve Conduits Filled with Collagen-Glycosaminoglycan Matrix on Peripheral Motor Nerve Regeneration in a Rat Model

(2012) Joo-Yup Lee et al.   JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME

Single Cyclized Molecule Versus Single Branched Molecule: A Simple and Efficient 3D “Knot” Polymer Structure for Nonviral Gene Delivery

(2012) Ben Newland et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cograft of neural stem cells and schwann cells overexpressing TrkC and neurotrophin-3 respectively after rat spinal cord transection

(2011) Jun-Mei Wang et al.   BIOMATERIALS

Comparison of polymer scaffolds in rat spinal cord: A step toward quantitative assessment of combinatorial approaches to spinal cord repair

(2011) Bingkun K. Chen et al.   BIOMATERIALS

Multifunctional, multichannel bridges that deliver neurotrophin encoding lentivirus for regeneration following spinal cord injury

(2011) Hannah M. Tuinstra et al.   BIOMATERIALS

The reverse of polymer degradation: in situ crosslinked gel formation through disulfide cleavage

(2011) Aram O. Saeed et al.   CHEMICAL COMMUNICATIONS

Chondroitinase ABC Promotes Recovery of Adaptive Limb Movements and Enhances Axonal Growth Caudal to a Spinal Hemisection

(2011) S. C. Jefferson et al.   JOURNAL OF NEUROSCIENCE

3D Single Cyclized Polymer Chain Structure from Controlled Polymerization of Multi-Vinyl Monomers: Beyond Flory–Stockmayer Theory

(2011) Yu Zheng et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A biomaterials approach to peripheral nerve regeneration: bridging the peripheral nerve gap and enhancing functional recovery

(2011) W. Daly et al.   Journal of the Royal Society Interface

Controlling dispersion of axonal regeneration using a multichannel collagen nerve conduit

(2010) Li Yao et al.   BIOMATERIALS

A highly effective gene delivery vector – hyperbranched poly(2-(dimethylamino)ethyl methacrylate) from in situ deactivation enhanced ATRP

(2010) Ben Newland et al.   CHEMICAL COMMUNICATIONS

Lentiviral vector-mediated knockdown of the neuroglycan 2 proteoglycan or expression of neurotrophin-3 promotes neurite outgrowth in a cell culture model of the glial scar

(2010) Eleanor M. Donnelly et al.   JOURNAL OF GENE MEDICINE

A reliable method for detecting complexed DNA in vitro

(2010) C. Holladay et al.   Nanoscale

Gait analysis of spinal cord injured rats after delivery of chondroitinase ABC and adult olfactory mucosa progenitor cell transplantation

(2010) Wen-Cheng Huang et al.   NEUROSCIENCE LETTERS

Multichanneled Collagen Conduits for Peripheral Nerve Regeneration: Design, Fabrication, and Characterization

(2010) Li Yao et al.   TISSUE ENGINEERING PART C-METHODS

Relationship between scaffold channel diameter and number of regenerating axons in the transected rat spinal cord

(2009) Aaron J. Krych et al.   Acta Biomaterialia

Local gene delivery from ECM-coated poly(lactide-co-glycolide) multiple channel bridges after spinal cord injury

(2009) Laura De Laporte et al.   BIOMATERIALS

MMP-9 controls Schwann cell proliferation and phenotypic remodeling via IGF-1 and ErbB receptor-mediated activation of MEK/ERK pathway

(2009) Sharmila Chattopadhyay et al.   GLIA

Adult neural stem cells expressing IL-10 confer potent immunomodulation and remyelination in experimental autoimmune encephalitis

(2009) Jingxian Yang et al.   JOURNAL OF CLINICAL INVESTIGATION

Axon Regeneration through Scaffold into Distal Spinal Cord after Transection

(2009) Bing Kun Chen et al.   JOURNAL OF NEUROTRAUMA

Biomaterial Design Strategies for the Treatment of Spinal Cord Injuries

(2009) Karin S. Straley et al.   JOURNAL OF NEUROTRAUMA

Sustained delivery of thermostabilized chABC enhances axonal sprouting and functional recovery after spinal cord injury

(2009) Hyunjung Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neural Stem Cell– and Schwann Cell–Loaded Biodegradable Polymer Scaffolds Support Axonal Regeneration in the Transected Spinal Cord

(2009) Heather E. Olson et al.   TISSUE ENGINEERING PART A

Functional restoration of rabbit spinal cord using collagen-filament scaffold

(2008) S. Yoshii et al.   Journal of Tissue Engineering and Regenerative Medicine

Plasmid Releasing Multiple Channel Bridges for Transgene Expression After Spinal Cord Injury

(2008) Laura De Laporte et al.   MOLECULAR THERAPY

Tissue-Engineered Platforms of Axon Guidance

(2008) Grace N. Li et al.   TISSUE ENGINEERING PART B-REVIEWS