BRCA1 gene therapy reduces systemic inflammatory response and multiple organ failure and improves survival in experimental sepsis

Decreased histone deacetylase 2 impairs Nrf2 activation by oxidative stress

(2011) Nicolas Mercado et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Propofol inhibits lipopolysaccharide-induced lung epithelial cell injury by reducing hypoxia-inducible factor-1α expression

(2011) C.-H. Yeh et al.   BRITISH JOURNAL OF ANAESTHESIA

Selective blockade of interleukin-6 trans-signaling improves survival in a murine polymicrobial sepsis model*

(2011) Tanja Barkhausen et al.   CRITICAL CARE MEDICINE

Human anti-microbial cathelicidin peptide LL-37 suppresses the LPS-induced apoptosis of endothelial cells

(2011) Kaori Suzuki et al.   INTERNATIONAL IMMUNOLOGY

Extracellular Administration of BCL2 Protein Reduces Apoptosis and Improves Survival in a Murine Model of Sepsis

(2011) Akiko Iwata et al.   PLoS One

Dose-Dependent Effect of Anti-CTLA-4 on Survival in Sepsis

(2011) Shigeaki Inoue et al.   SHOCK

BRCA1 is an essential regulator of heart function and survival following myocardial infarction

(2011) Praphulla C. Shukla et al.   Nature Communications

Reactivity of mouse alveolar macrophages to cigarette smoke is strain dependent

(2010) Daniela Vecchio et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

The Surviving Sepsis Campaign: Results of an international guideline-based performance improvement program targeting severe sepsis*

(2010) Mitchell M. Levy et al.   CRITICAL CARE MEDICINE

3,3′-Diindolylmethane decreases VCAM-1 expression and alleviates experimental colitis via a BRCA1-dependent antioxidant pathway

(2010) Zhen Huang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Caveolin-1 Protects against Sepsis by Modulating Inflammatory Response, Alleviating Bacterial Burden, and Suppressing Thymocyte Apoptosis

(2010) Hong Feng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Insights Into Sepsis Therapeutic Design Based on the Apoptotic Death Pathway

(2010) Yuichi Hattori et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Increased death receptor pathway of apoptotic signaling in septic mouse aorta: effect of systemic delivery of FADD siRNA

(2009) Naoyuki Matsuda et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Syncope While Driving

(2009) Dan Sorajja et al.   CIRCULATION

Activated protein C for the treatment of severe sepsis

(2009) G. Houston et al.   CLINICAL MICROBIOLOGY AND INFECTION

IL-15 Prevents Apoptosis, Reverses Innate and Adaptive Immune Dysfunction, and Improves Survival in Sepsis

(2009) S. Inoue et al.   JOURNAL OF IMMUNOLOGY

Overexpression of Hsp20 prevents endotoxin-induced myocardial dysfunction and apoptosis via inhibition of NF-κB activation

(2009) Xiaohong Wang et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Calpain-1 induces apoptosis in pulmonary microvascular endothelial cells under septic conditions

(2009) Houxiang Hu et al.   MICROVASCULAR RESEARCH

Recognition of DNA double strand breaks by the BRCA1 tumor suppressor network

(2008) Roger A. Greenberg   CHROMOSOMA

Apoptosis in Sepsis: Mechanisms, Clinical Impact and Potential Therapeutic Targets

(2008) Alfred Ayala et al.   CURRENT PHARMACEUTICAL DESIGN

Sepsis: rethinking the approach to clinical research

(2008) John C. Marshall   JOURNAL OF LEUKOCYTE BIOLOGY

Regulation of endothelial barrier function by reactive oxygen and nitrogen species

(2008) Adel Boueiz et al.   MICROVASCULAR RESEARCH

THE ROLE OF NEUTROPHILS IN SEVERE SEPSIS

(2008) José C. Alves-Filho et al.   SHOCK

Altered Nrf2/Keap1-Bach1 equilibrium in pulmonary emphysema

(2008) D Goven et al.   THORAX