Non-hematopoietic stem cells as factories for in vivo therapeutic protein production

Hierarchical scaffold design for mesenchymal stem cell-based gene therapy of hemophilia B

(2010) Daniel L. Coutu et al.   BIOMATERIALS

Adipose-Derived Mesenchymal Stem Cells as Stable Source of Tumor Necrosis Factor–Related Apoptosis-Inducing Ligand Delivery for Cancer Therapy

(2010) Giulia Grisendi et al.   CANCER RESEARCH

Insulin expressed from endogenously active glucose-responsive EGR1 promoter in bone marrow mesenchymal stromal cells as diabetes therapy

(2010) N K F Chen et al.   GENE THERAPY

Toward Brain Tumor Gene Therapy Using Multipotent Mesenchymal Stromal Cell Vectors

(2010) Daniel Bexell et al.   MOLECULAR THERAPY

Concise Review: Stem Cells As an Emerging Platform for Antibody Therapy of Cancer

(2010) Richard T. Frank et al.   STEM CELLS

Mesenchymal Stem Cell Delivery of TRAIL Can Eliminate Metastatic Cancer

(2009) M. R. Loebinger et al.   CANCER RESEARCH

Intravenous hMSCs Improve Myocardial Infarction in Mice because Cells Embolized in Lung Are Activated to Secrete the Anti-inflammatory Protein TSG-6

(2009) Ryang Hwa Lee et al.   Cell Stem Cell

Mesenchymal Stem Cell Homing: The Devil Is in the Details

(2009) Jeffrey M. Karp et al.   Cell Stem Cell

Encapsulated human mesenchymal stem cells: a unique hypoimmunogenic platform for long-term cellular therapy

(2009) Amit Goren et al.   FASEB JOURNAL

Progress and prospects: immune responses to viral vectors

(2009) S Nayak et al.   GENE THERAPY

Three-dimensional porous scaffolds at the crossroads of tissue engineering and cell-based gene therapy

(2009) Daniel L. Coutu et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Intratumoral IL-7 delivery by mesenchymal stromal cells potentiates IFNγ-transduced tumor cell immunotherapy of experimental glioma

(2009) Salina Gunnarsson et al.   JOURNAL OF NEUROIMMUNOLOGY

Intravenous mesenchymal stem cell therapy for traumatic brain injury

(2009) Matthew T. Harting et al.   JOURNAL OF NEUROSURGERY

Casting Doubt on the Safety of “Off-the-shelf” Mesenchymal Stem Cells for Cell Therapy

(2009) Pranela Rameshwar   MOLECULAR THERAPY

Autologous Bone Marrow Stromal Cells Genetically Engineered to Secrete an IGF-I Receptor Decoy Prevent the Growth of Liver Metastases

(2009) Ni Wang et al.   MOLECULAR THERAPY

Biological Gene Delivery Vehicles: Beyond Viral Vectors

(2009) Yiqi Seow et al.   MOLECULAR THERAPY

Repair of Tissues by Adult Stem/Progenitor Cells (MSCs): Controversies, Myths, and Changing Paradigms

(2009) Darwin J Prockop   MOLECULAR THERAPY

ANTITUMOR TREATMENT USING INTERLEUKIN‐12‐SECRETING MARROW STROMAL CELLS IN AN INVASIVE GLIOMA MODEL

(2009) Xin Hong et al.   NEUROSURGERY

Neural Stem Cells as a Novel Platform for Tumor-Specific Delivery of Therapeutic Antibodies

(2009) Richard T. Frank et al.   PLoS One

Assessment of therapeutic efficacy and fate of engineered human mesenchymal stem cells for cancer therapy

(2009) L. S. Sasportas et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Trafficking Mesenchymal Stem Cell Engraftment and Differentiation in Tumor-Bearing Mice by Bioluminescence Imaging

(2009) Hui Wang et al.   STEM CELLS

Human Bone Marrow-Derived Mesenchymal Stromal Cells Expressing S-TRAIL as a Cellular Delivery Vehicle for Human Glioma Therapy

(2009) Lata G. Menon et al.   STEM CELLS

Anti-angiogenesis therapy based on the bone marrow-derived stromal cells genetically engineered to express sFlt-1 in mouse tumor model

(2008) M Hu et al.   BMC CANCER

Murine bone marrow-derived mesenchymal stem cells as vehicles for interleukin-12 gene delivery into Ewing sarcoma tumors

(2008) Xiaoping Duan et al.   CANCER

Neo-Organoid of Marrow Mesenchymal Stromal Cells Secreting Interleukin-12 for Breast Cancer Therapy

(2008) N. Eliopoulos et al.   CANCER RESEARCH

Gene Therapy Using TRAIL-Secreting Human Umbilical Cord Blood-Derived Mesenchymal Stem Cells against Intracranial Glioma

(2008) S. M. Kim et al.   CANCER RESEARCH

Adenoviral-mediated interleukin-18 expression in mesenchymal stem cells effectively suppresses the growth of glioma in rats

(2008) Gang Xu et al.   CELL BIOLOGY INTERNATIONAL

Stem and progenitor cell-mediated tumor selective gene therapy

(2008) K S Aboody et al.   GENE THERAPY

Cancer gene therapy using mesenchymal stem cells expressing interferon-β in a mouse prostate cancer lung metastasis model

(2008) C Ren et al.   GENE THERAPY

Cell vehicle targeting strategies

(2008) J C Roth et al.   GENE THERAPY

Long-term in vivo imaging of human angiogenesis: Critical role of bone marrow-derived mesenchymal stem cells for the generation of durable blood vessels

(2008) Laura Sanz et al.   MICROVASCULAR RESEARCH

A Tumor-selective Biotherapy With Prolonged Impact on Established Metastases Based on Cytokine Gene-engineered MSCs

(2008) Xiancheng Chen et al.   MOLECULAR THERAPY

Mesenchymal Stromal Cells Engineered to Express Erythropoietin Induce Anti-erythropoietin Antibodies and Anemia in Allorecipients

(2008) Philippe M Campeau et al.   MOLECULAR THERAPY

Bone Marrow Multipotent Mesenchymal Stroma Cells Act as Pericyte-like Migratory Vehicles in Experimental Gliomas

(2008) Daniel Bexell et al.   MOLECULAR THERAPY

Therapeutic Potential of Mesenchymal Stem Cells Producing Interferon-α in a Mouse Melanoma Lung Metastasis Model

(2008) Changchun Ren et al.   STEM CELLS

Lentiviral-Transduced Human Mesenchymal Stem Cells Persistently Express Therapeutic Levels of Enzyme in a Xenotransplantation Model of Human Disease

(2008) Todd E. Meyerrose et al.   STEM CELLS

Antitumoral Activity and Osteogenic Potential of Mesenchymal Stem Cells Expressing the Urokinase-Type Plasminogen Antagonist Amino-Terminal Fragment in a Murine Model of Osteolytic Tumor

(2008) Vanessa Fritz et al.   STEM CELLS

Tumor Immunotherapy Using Gene-Modified Human Mesenchymal Stem Cells Loaded into Synthetic Extracellular Matrix Scaffolds

(2008) Marta Compte et al.   STEM CELLS

Pulmonary Passage is a Major Obstacle for Intravenous Stem Cell Delivery: The Pulmonary First-Pass Effect

(2008) Uwe M. Fischer et al.   STEM CELLS AND DEVELOPMENT