Gene therapy for retinal ganglion cell neuroprotection in glaucoma

Retinal Ganglion Cell Gene Therapy and Visual System Repair

(2011) Mats Hellstrom et al.   CURRENT GENE THERAPY

Ocular neuroprotection by siRNA targeting caspase-2

(2011) Z Ahmed et al.   Cell Death & Disease

Leber Hereditary Optic Neuropathy Gene Therapy Clinical Trial Recruitment

(2010) Byron L. Lam   ARCHIVES OF OPHTHALMOLOGY

Superoxide is an associated signal for apoptosis in axonal injury

(2010) A. Kanamori et al.   BRAIN

Glaucoma: genes, phenotypes, and new directions for therapy

(2010) Bao Jian Fan et al.   JOURNAL OF CLINICAL INVESTIGATION

Long-Distance Axon Regeneration in the Mature Optic Nerve: Contributions of Oncomodulin, cAMP, and pten Gene Deletion

(2010) T. Kurimoto et al.   JOURNAL OF NEUROSCIENCE

Real-Time Dynamics of Ca2+, Caspase-3/7, and Morphological Changes in Retinal Ganglion Cell Apoptosis under Elevated Pressure

(2010) Jae Kyoo Lee et al.   PLoS One

Distal axonopathy with structural persistence in glaucomatous neurodegeneration

(2010) S. D. Crish et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Recent clinical findings with memantine should not mean that the idea of neuroprotection in glaucoma is abandoned

(2009) Neville N. Osborne   ACTA OPHTHALMOLOGICA

In vivo gene regulation using tetracycline-regulatable systems

(2009) Knut Stieger et al.   ADVANCED DRUG DELIVERY REVIEWS

Kv1.1 and Kv1.3 channels contribute to the degeneration of retinal ganglion cells after optic nerve transection in vivo

(2009) P D Koeberle et al.   CELL DEATH AND DIFFERENTIATION

Friend or Foe? Resolving the Impact of Glial Responses in Glaucoma

(2009) Elaine C. Johnson et al.   JOURNAL OF GLAUCOMA

Excitotoxic Death of Retinal Neurons In Vivo Occurs via a Non-Cell-Autonomous Mechanism

(2009) F. Lebrun-Julien et al.   JOURNAL OF NEUROSCIENCE

Mst3b, an Ste20-like kinase, regulates axon regeneration in mature CNS and PNS pathways

(2009) Barbara Lorber et al.   NATURE NEUROSCIENCE

Gene Therapy Targeting Glaucoma: Where Are We?

(2009) Xuyang Liu et al.   SURVEY OF OPHTHALMOLOGY

Optimized Allotopic Expression of the Human Mitochondrial ND4 Prevents Blindness in a Rat Model of Mitochondrial Dysfunction

(2008) Sami Ellouze et al.   AMERICAN JOURNAL OF HUMAN GENETICS

BAG1 promotes axonal outgrowth and regeneration in vivo via Raf-1 and reduction of ROCK activity

(2008) Véronique Planchamp et al.   BRAIN

Haem oxygenase-1 gene transfer protects retinal ganglion cells from ischaemia/reperfusion injury

(2008) Pai-Huei Peng et al.   CLINICAL SCIENCE

Cellular tropism and transduction properties of seven adeno-associated viral vector serotypes in adult retina after intravitreal injection

(2008) M Hellström et al.   GENE THERAPY

Inhibition of p75NTR in glia potentiates TrkA-mediated survival of injured retinal ganglion cells

(2008) Frédéric Lebrun-Julien et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Detection of Intact rAAV Particles up to 6 Years After Successful Gene Transfer in the Retina of Dogs and Primates

(2008) Knut Stieger et al.   MOLECULAR THERAPY

Promoting Axon Regeneration in the Adult CNS by Modulation of the PTEN/mTOR Pathway

(2008) K. K. Park et al.   SCIENCE

Barriers for retinal gene therapy: Separating fact from fiction

(2008) Rajendra Kumar-Singh   VISION RESEARCH