Experimental vaccines against potentially pandemic and highly pathogenic avian influenza viruses

Cell culture-derived influenza vaccines from Vero cells: a new horizon for vaccine production

(2012) Emanuele Montomoli et al.   Expert Review of Vaccines

Glycan-Dependent Immunogenicity of Recombinant Soluble Trimeric Hemagglutinin

(2012) R. P. de Vries et al.   JOURNAL OF VIROLOGY

Temporal expression of microRNA cluster miR-17-92 regulates effector and memory CD8+ T-cell differentiation

(2012) T. Wu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Broadly neutralizing antibodies against influenza virus and prospects for universal therapies

(2012) Damian C Ekiert et al.   Current Opinion in Virology

The first influenza pandemic of the new millennium

(2011) Gabriele Neumann et al.   Influenza and Other Respiratory Viruses

Vesicular Stomatitis Virus-Based H5N1 Avian Influenza Vaccines Induce Potent Cross-Clade Neutralizing Antibodies in Rhesus Macaques

(2011) J. A. Schwartz et al.   JOURNAL OF VIROLOGY

DNA priming and influenza vaccine immunogenicity: two phase 1 open label randomised clinical trials

(2011) Julie E Ledgerwood et al.   LANCET INFECTIOUS DISEASES

Cold-Adapted Influenza and Recombinant Adenovirus Vaccines Induce Cross-Protective Immunity against pH1N1 Challenge in Mice

(2011) Mark R. Soboleski et al.   PLoS One

Adaptation of High-Growth Influenza H5N1 Vaccine Virus in Vero Cells: Implications for Pandemic Preparedness

(2011) Yu-Fen Tseng et al.   PLoS One

Evaluation of the safety, reactogenicity and immunogenicity of FluBlok® trivalent recombinant baculovirus-expressed hemagglutinin influenza vaccine administered intramuscularly to healthy adults 50–64 years of age☆

(2011) R. Baxter et al.   VACCINE

Protective efficacy of a trivalent recombinant hemagglutinin protein vaccine (FluBlok®) against influenza in healthy adults: A randomized, placebo-controlled trial

(2011) John J. Treanor et al.   VACCINE

Parainfluenza virus 5-based vaccine vectors expressing vaccinia virus (VACV) antigens provide long-term protection in mice from lethal intranasal VACV challenge

(2011) Kimberly M. Clark et al.   VIROLOGY

Comparison of differing cytopathic effects in human airway epithelium of parainfluenza virus 5 (W3A), parainfluenza virus type 3, and respiratory syncytial virus

(2011) Liqun Zhang et al.   VIROLOGY

Influenza virus vaccines: lessons from the 2009 H1N1 pandemic

(2011) Andrew J Broadbent et al.   Current Opinion in Virology

Potent CD8+ T-Cell Immunogenicity in Humans of a Novel Heterosubtypic Influenza A Vaccine, MVA-NP+M1

(2010) T. K. Berthoud et al.   CLINICAL INFECTIOUS DISEASES

Baculovirus as Vaccine Vectors

(2010) Selvaraj Madhan et al.   CURRENT GENE THERAPY

Egg-independent vaccine strategies for highly pathogenic H5N1 influenza viruses

(2010) Aseem Pandey et al.   Human vaccines & immunotherapeutics

DNA vaccines: an historical perspective and view to the future

(2010) Margaret A. Liu   IMMUNOLOGICAL REVIEWS

How RNA viruses maintain their genome integrity

(2010) J. N. Barr et al.   JOURNAL OF GENERAL VIROLOGY

Potent Vesicular Stomatitis Virus-Based Avian Influenza Vaccines Provide Long-Term Sterilizing Immunity against Heterologous Challenge

(2010) J. A. Schwartz et al.   JOURNAL OF VIROLOGY

Rationalizing the development of live attenuated virus vaccines

(2010) Adam S Lauring et al.   NATURE BIOTECHNOLOGY

Induction of Broadly Neutralizing H1N1 Influenza Antibodies by Vaccination

(2010) C.-J. Wei et al.   SCIENCE

Long-Term Thermostabilization of Live Poxviral and Adenoviral Vaccine Vectors at Supraphysiological Temperatures in Carbohydrate Glass

(2010) R. Alcock et al.   Science Translational Medicine

Induction of neutralizing antibodies to Hendra and Nipah glycoproteins using a Venezuelan equine encephalitis virus in vivo expression system

(2010) Gabriel N. Defang et al.   VACCINE

Hemagglutinin Displayed Baculovirus Protects Against Highly Pathogenic Influenza

(2010) Xian-Chun Tang et al.   VACCINE

Baculovirus as an avian influenza vaccine vector: Differential immune responses elicited by different vector forms

(2010) Chi-Yuan Chen et al.   VACCINE

Respiratory tract immunization of non-human primates with a Newcastle disease virus-vectored vaccine candidate against Ebola virus elicits a neutralizing antibody response

(2010) Joshua M. DiNapoli et al.   VACCINE

Phase 1 clinical trials of the safety and immunogenicity of adjuvanted plasmid DNA vaccines encoding influenza A virus H5 hemagglutinin

(2010) Larry R. Smith et al.   VACCINE

Mucosal parainfluenza virus-vectored vaccine against Ebola virus replicates in the respiratory tract of vector-immune monkeys and is immunogenic

(2010) Alexander A. Bukreyev et al.   VIROLOGY

Protective immunity against H5N1 influenza virus by a single dose vaccination with virus-like particles

(2010) Jae-Min Song et al.   VIROLOGY

Influenza Virus Vaccine Based on the Conserved Hemagglutinin Stalk Domain

(2010) J. Steel et al.   mBio

FluBlok, a next generation influenza vaccine manufactured in insect cells

(2009) Manon M.J. Cox et al.   BIOLOGICALS

Recombinant Vesicular Stomatitis Virus Expressing Influenza Nucleoprotein Induces CD8 T-Cell Responses That Enhance Antibody-Mediated Protection after Lethal Challenge with Influenza Virus

(2009) B. E. Barefoot et al.   Clinical and Vaccine Immunology

Opportunities and challenges of developing thermostable vaccines

(2009) Dexiang Chen et al.   Expert Review of Vaccines

Vero cell platform in vaccine production: moving towards cell culture-based viral vaccines

(2009) P Noel Barrett et al.   Expert Review of Vaccines

Vaccinia Virus-Based Multivalent H5N1 Avian Influenza Vaccines Adjuvanted with IL-15 Confer Sterile Cross-Clade Protection in Mice

(2009) L. L. M. Poon et al.   JOURNAL OF IMMUNOLOGY

Newcastle Disease Virus-Vectored Vaccines Expressing the Hemagglutinin or Neuraminidase Protein of H5N1 Highly Pathogenic Avian Influenza Virus Protect against Virus Challenge in Monkeys

(2009) J. M. DiNapoli et al.   JOURNAL OF VIROLOGY

Contributions of the Avian Influenza Virus HA, NA, and M2 Surface Proteins to the Induction of Neutralizing Antibodies and Protective Immunity

(2009) B. Nayak et al.   JOURNAL OF VIROLOGY

A pseudotype baculovirus-mediated vaccine confers protective immunity against lethal challenge with H5N1 avian influenza virus in mice and chickens

(2009) Qunfeng Wu et al.   MOLECULAR IMMUNOLOGY

New Insights on Adenovirus as Vaccine Vectors

(2009) Marcio O Lasaro et al.   MOLECULAR THERAPY

Viruses as vaccine vectors for infectious diseases and cancer

(2009) Simon J. Draper et al.   NATURE REVIEWS MICROBIOLOGY

MVA-Based H5N1 Vaccine Affords Cross-Clade Protection in Mice against Influenza A/H5N1 Viruses at Low Doses and after Single Immunization

(2009) Joost H. C. M. Kreijtz et al.   PLoS One

Intramuscular immunization with a vesicular stomatitis virus recombinant expressing the influenza hemagglutinin provides post-exposure protection against lethal influenza challenge

(2009) Brice E. Barefoot et al.   VACCINE

Evaluation of the safety, reactogenicity and immunogenicity of FluBlok® trivalent recombinant baculovirus-expressed hemagglutinin influenza vaccine administered intramuscularly to healthy children aged 6–59 months

(2009) James C. King et al.   VACCINE

A recombinant vesicular stomatitis virus replicon vaccine protects chickens from highly pathogenic avian influenza virus (H7N1)

(2009) Nazeer H. Kalhoro et al.   VACCINE

Evaluation of two live attenuated cold-adapted H5N1 influenza virus vaccines in healthy adults

(2009) Ruth A. Karron et al.   VACCINE

Alphavirus replicon particle vaccines developed for use in humans induce high levels of antibodies to influenza virus hemagglutinin in swine: Proof of concept

(2009) M.M. Erdman et al.   VACCINE

Priming with AS03A-adjuvanted H5N1 influenza vaccine improves the kinetics, magnitude and durability of the immune response after a heterologous booster vaccination: An open non-randomised extension of a double-blind randomised primary study

(2009) Isabel Leroux-Roels et al.   VACCINE

Harnessing Endogenous miRNAs to Control Virus Tissue Tropism as a Strategy for Developing Attenuated Virus Vaccines

(2008) Dwight Barnes et al.   Cell Host & Microbe

Clinical development of MVA-based therapeutic cancer vaccines

(2008) Bruce Acres et al.   Expert Review of Vaccines

MF59® -adjuvanted vaccines for seasonal and pandemic influenza prophylaxis

(2008) Angelika Banzhoff et al.   Influenza and Other Respiratory Viruses

Vaccination with a Modified Vaccinia Virus Ankara-based vaccine protects mice from allergic sensitization

(2008) Melanie Albrecht et al.   JOURNAL OF GENE MEDICINE

A Broadly Protective Vaccine against Globally Dispersed Clade 1 and Clade 2 H5N1 Influenza Viruses

(2008) Mary A. Hoelscher et al.   JOURNAL OF INFECTIOUS DISEASES

Recombinant Newcastle Disease Virus as a Vaccine Vector for Cancer Therapy

(2008) Adam Vigil et al.   MOLECULAR THERAPY

Bovine Adenoviral Vector–based H5N1 Influenza Vaccine Overcomes Exceptionally High Levels of Pre-existing Immunity Against Human Adenovirus

(2008) Neetu Singh et al.   MOLECULAR THERAPY

Influenza virus-like particles produced by transient expression inNicotiana benthamianainduce a protective immune response against a lethal viral challenge in mice

(2008) Marc-André D’Aoust et al.   PLANT BIOTECHNOLOGY JOURNAL

Broad Clade 2 Cross-Reactive Immunity Induced by an Adjuvanted Clade 1 rH5N1 Pandemic Influenza Vaccine

(2008) Isabel Leroux-Roels et al.   PLoS One

Cross-Protection against Lethal H5N1 Challenge in Ferrets with an Adjuvanted Pandemic Influenza Vaccine

(2008) Benoît Baras et al.   PLoS One

Heterosubtypic Protection against Pathogenic Human and Avian Influenza Viruses via In Vivo Electroporation of Synthetic Consensus DNA Antigens

(2008) Dominick J. Laddy et al.   PLoS One

Nasal Delivery of an Adenovirus-Based Vaccine Bypasses Pre-Existing Immunity to the Vaccine Carrier and Improves the Immune Response in Mice

(2008) Maria A. Croyle et al.   PLoS One

H5N1 VLP vaccine induced protection in ferrets against lethal challenge with highly pathogenic H5N1 influenza viruses

(2008) Kutubuddin Mahmood et al.   VACCINE

Multi-antigen vaccines based on complex adenovirus vectors induce protective immune responses against H5N1 avian influenza viruses

(2008) David H. Holman et al.   VACCINE

Differential mechanisms of complement-mediated neutralization of the closely related paramyxoviruses simian virus 5 and mumps virus

(2008) John B. Johnson et al.   VIROLOGY

Virus growth and antibody responses following respiratory tract infection of ferrets and mice with WT and P/V mutants of the paramyxovirus Simian Virus 5

(2008) Gerald A. Capraro et al.   VIROLOGY

SARS vaccine based on a replication-defective recombinant vesicular stomatitis virus is more potent than one based on a replication-competent vector

(2008) Sagar U. Kapadia et al.   VIROLOGY

Vesicular Stomatitis Virus-Based Ebola Vaccine Is Well-Tolerated and Protects Immunocompromised Nonhuman Primates

(2008) Thomas W. Geisbert et al.   PLoS Pathogens