Emerging personalized oncology: sequencing and systems strategies

Differential network biology

(2012) Trey Ideker et al.   Molecular Systems Biology

Modular regulatory principles of large non-coding RNAs

(2012) Mitchell Guttman et al.   NATURE

Clonal evolution in relapsed acute myeloid leukaemia revealed by whole-genome sequencing

(2012) Li Ding et al.   NATURE

Realizing Genomic Medicine

(2012) Elizabeth G. Phimister et al.   NEW ENGLAND JOURNAL OF MEDICINE

Preparing for Precision Medicine

(2012) Reza Mirnezami et al.   NEW ENGLAND JOURNAL OF MEDICINE

Tumour evolution inferred by single-cell sequencing

(2011) Nicholas Navin et al.   NATURE

Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders

(2011) Darren J. Baker et al.   NATURE

Charting a course for genomic medicine from base pairs to bedside

(2011) Eric D. Green et al.   NATURE

Performance comparison of whole-genome sequencing platforms

(2011) Hugo Y K Lam et al.   NATURE BIOTECHNOLOGY

Improved Survival with Vemurafenib in Melanoma with BRAF V600E Mutation

(2011) Paul B. Chapman et al.   NEW ENGLAND JOURNAL OF MEDICINE

Everolimus in Postmenopausal Hormone-Receptor–Positive Advanced Breast Cancer

(2011) José Baselga et al.   NEW ENGLAND JOURNAL OF MEDICINE

Pertuzumab plus Trastuzumab plus Docetaxel for Metastatic Breast Cancer

(2011) José Baselga et al.   NEW ENGLAND JOURNAL OF MEDICINE

Trastuzumab

(2011) A. H. Boekhout et al.   ONCOLOGIST

Exploring the Genomes of Cancer Cells: Progress and Promise

(2011) M. R. Stratton   SCIENCE

Personalized Oncology Through Integrative High-Throughput Sequencing: A Pilot Study

(2011) S. Roychowdhury et al.   Science Translational Medicine

Next-generation, genome sequencing-based biomarkers: concerns and challenges for medical practice

(2010) Dimitrios H Roukos   Biomarkers in Medicine

Genotype–phenotype map and molecular networks: a promising solution in overcoming colorectal cancer resistance to targeted treatment

(2010) Dimitrios H Roukos et al.   EXPERT REVIEW OF MOLECULAR DIAGNOSTICS

Genome remodelling in a basal-like breast cancer metastasis and xenograft

(2010) Li Ding et al.   NATURE

Distant metastasis occurs late during the genetic evolution of pancreatic cancer

(2010) Shinichi Yachida et al.   NATURE

International network of cancer genome projects

(2010) Thomas J. Hudson (Chairperson) et al.   NATURE

Complete genome sequencing and network modeling to overcome trastuzumab resistance

(2010) Dimitrios H Roukos   PHARMACOGENOMICS