Bacterial glycosidases in pathogenesis and glycoengineering

Chemoenzymatic Fc Glycosylation via Engineered Aldehyde Tags

(2014) Elizabeth L. Smith et al.   BIOCONJUGATE CHEMISTRY

Disease Manifestations and Pathogenic Mechanisms of Group A Streptococcus

(2014) M. J. Walker et al.   CLINICAL MICROBIOLOGY REVIEWS

Fragments of Bacterial Endoglycosidase S and Immunoglobulin G Reveal Subdomains of Each That Contribute to Deglycosylation

(2014) Emma V. Dixon et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

EndoE from Enterococcus faecalis Hydrolyzes the Glycans of the Biofilm Inhibiting Protein Lactoferrin and Mediates Growth

(2014) Julia Garbe et al.   PLoS One

Crystal structure of Streptococcus pyogenes EndoS, an immunomodulatory endoglycosidase specific for human IgG antibodies

(2014) B. Trastoy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

EndoS2is a unique and conserved enzyme of serotype M49 group AStreptococcusthat hydrolyses N-linked glycans on IgG and α1-acid glycoprotein

(2013) Jonathan Sjögren et al.   BIOCHEMICAL JOURNAL

A two-step enzymatic glycosylation of polypeptides with complex N -glycans

(2013) Joseph V. Lomino et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Inhibition of HPA-1a alloantibody-mediated platelet destruction by a deglycosylated anti-HPA-1a monoclonal antibody in mice: toward targeted treatment of fetal-alloimmune thrombocytopenia

(2013) T. Bakchoul et al.   BLOOD

Natural variation in Fc glycosylation of HIV-specific antibodies impacts antiviral activity

(2013) Margaret E. Ackerman et al.   JOURNAL OF CLINICAL INVESTIGATION

Identification and epidemiological relatedness of clinical Elizabethkingia meningoseptica isolates from central Taiwan

(2013) Yi-Cheng Chang et al.   JOURNAL OF MICROBIOLOGY IMMUNOLOGY AND INFECTION

A surface-exposed neuraminidase affects complement resistance and virulence of the oral spirochaeteTreponema denticola

(2013) Kurni Kurniyati et al.   MOLECULAR MICROBIOLOGY

Microbiota-liberated host sugars facilitate post-antibiotic expansion of enteric pathogens

(2013) Katharine M. Ng et al.   NATURE

Inducing host protection in pneumococcal sepsis by preactivation of the Ashwell-Morell receptor

(2013) P. K. Grewal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Listeria monocytogenes ChiA Chitinase Enhances Virulence through Suppression of Host Innate Immunity

(2013) S. Chaudhuri et al.   mBio

Enzymatic deglycosylation converts pathogenic neuromyelitis optica anti-aquaporin-4 immunoglobulin G into therapeutic antibody

(2012) Lukmanee Tradtrantip et al.   ANNALS OF NEUROLOGY

IgG glycan hydrolysis by endoglycosidase S diminishes the proinflammatory properties of immune complexes from patients with systemic lupus erythematosus: A possible new treatment?

(2012) Christian Lood et al.   ARTHRITIS AND RHEUMATISM

Strategies for the profiling, characterisation and detailed structural analysis of N-linked oligosaccharides

(2012) Tharmala Tharmalingam et al.   GLYCOCONJUGATE JOURNAL

Antiphagocytic Function of an IgG Glycosyl Hydrolase from Streptococcus equi subsp.equiand Its Use as a Vaccine Component

(2012) Margareta Flock et al.   INFECTION AND IMMUNITY

Enzymatic autoantibody glycan hydrolysis alleviates autoimmunity against type VII collagen

(2012) Misa Hirose et al.   JOURNAL OF AUTOIMMUNITY

Remarkable Transglycosylation Activity of Glycosynthase Mutants of Endo-D, an Endo-β-N-acetylglucosaminidase fromStreptococcus pneumoniae

(2012) Shu-Quan Fan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Bacterial Hydrolysis of Host Glycoproteins – Powerful Protein Modification and Efficient Nutrient Acquisition

(2012) Julia Garbe et al.   Journal of Innate Immunity

Selective Deactivation of Serum IgG: A General Strategy for the Enhancement of Monoclonal Antibody Receptor Interactions

(2012) Kavitha Baruah et al.   JOURNAL OF MOLECULAR BIOLOGY

IgG glycan hydrolysis by EndoS inhibits experimental autoimmune encephalomyelitis

(2012) Mahdia Benkhoucha et al.   Journal of Neuroinflammation

Chemoenzymatic Glycoengineering of Intact IgG Antibodies for Gain of Functions

(2012) Wei Huang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Endo-β-N-acetylglucosaminidases from Infant Gut-associated Bifidobacteria Release ComplexN-glycans from Human Milk Glycoproteins

(2012) Daniel Garrido et al.   MOLECULAR & CELLULAR PROTEOMICS

Structural analysis of a putative family 32 carbohydrate-binding module from theStreptococcus pneumoniaeenzyme EndoD

(2011) D. Wade Abbott et al.   Acta Crystallographica Section F-Structural Biology and Crystallization Communications

Study of the IgG endoglycosidase EndoS in group A streptococcal phagocyte resistance and virulence

(2011) Jonathan Sjögren et al.   BMC MICROBIOLOGY

An endo-β-N-acetylglucosaminidase from Enterococcus faecalisV583 responsible for the hydrolysis of high-mannose and hybrid-type N-linked glycans

(2011) Liv Anette Bøhle et al.   FEMS MICROBIOLOGY LETTERS

High-mannose glycans on the Fc region of therapeutic IgG antibodies increase serum clearance in humans

(2011) A. M. Goetze et al.   GLYCOBIOLOGY

Hydrolysis of Secreted Sialoglycoprotein Immunoglobulin A (IgA) inex Vivoand Biochemical Models of Bacterial Vaginosis

(2011) Warren G. Lewis et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

High Throughput Isolation and Glycosylation Analysis of IgG–Variability and Heritability of the IgG Glycome in Three Isolated Human Populations

(2011) Maja Pučić et al.   MOLECULAR & CELLULAR PROTEOMICS

Inhibition of the Pneumococcal Virulence Factor StrH and Molecular Insights into N-Glycan Recognition and Hydrolysis

(2011) Benjamin Pluvinage et al.   STRUCTURE

Are pathogenic bacteria just looking for food? Metabolism and microbial pathogenesis

(2011) Laurence Rohmer et al.   TRENDS IN MICROBIOLOGY

The N-glycan Glycoprotein Deglycosylation Complex (Gpd) from Capnocytophaga canimorsus Deglycosylates Human IgG

(2011) Francesco Renzi et al.   PLoS Pathogens

Mucolytic Bacteria With Increased Prevalence in IBD Mucosa Augment In Vitro Utilization of Mucin by Other Bacteria

(2010) Chin Wen Png et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

N-Glycosylation Augmentation of the Cystic Fibrosis Epithelium ImprovesPseudomonas aeruginosaClearance

(2010) Ashley T. Martino et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Glycan labeling strategies and their use in identification and quantification

(2010) L. R. Ruhaak et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Contribution of Chitinases to Listeria monocytogenes Pathogenesis

(2010) S. Chaudhuri et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

The IgG-specific endoglycosidase EndoS inhibits both cellular and complement-mediated autoimmune hemolysis

(2010) M. Allhorn et al.   BLOOD

A Novel Role for the IgG Fc Glycan: The Anti-inflammatory Activity of Sialylated IgG Fcs

(2010) Robert M. Anthony et al.   JOURNAL OF CLINICAL IMMUNOLOGY

IgG Glycan Hydrolysis Attenuates ANCA-Mediated Glomerulonephritis

(2010) M. M. van Timmeren et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Pneumococcal modification of host sugars: a major contributor to colonization of the human airway?

(2010) S.J. King   Molecular Oral Microbiology

Successful treatment of experimental glomerulonephritis with IdeS and EndoS, IgG-degrading streptococcal enzymes

(2010) R. Yang et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Targeted metabolic labeling of yeast N-glycans with unnatural sugars

(2010) M. A. Breidenbach et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of a Pneumococcal Glycosidase That Modifies O-Linked Glycans

(2009) C. Marion et al.   INFECTION AND IMMUNITY

The surface-anchored NanA protein promotes pneumococcal brain endothelial cell invasion

(2009) Satoshi Uchiyama et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Comparison of Methods for ProfilingO-Glycosylation

(2009) Yoshinao Wada et al.   MOLECULAR & CELLULAR PROTEOMICS

Glycosylation as a strategy to improve antibody-based therapeutics

(2009) Roy Jefferis   NATURE REVIEWS DRUG DISCOVERY

Glycosidases: a key to tailored carbohydrates

(2009) Pavla Bojarová et al.   TRENDS IN BIOTECHNOLOGY

Molecular cloning, expression, and characterization of a novel endo-α-N-acetylgalactosaminidase from Enterococcus faecalis

(2008) Hatsumi M. Goda et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Novel endo- -N-acetylgalactosaminidases with broader substrate specificity

(2008) D. Koutsioulis et al.   GLYCOBIOLOGY

The Structural Basis for T-antigen Hydrolysis byStreptococcus pneumoniae

(2008) Matthew E. C. Caines et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Ashwell receptor mitigates the lethal coagulopathy of sepsis

(2008) Prabhjit K Grewal et al.   NATURE MEDICINE

Human IgG/FcγR Interactions Are Modulated by Streptococcal IgG Glycan Hydrolysis

(2008) Maria Allhorn et al.   PLoS One

A direct link between carbohydrate utilization and virulence in the major human pathogen group A Streptococcus

(2008) S. A. Shelburne et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The role of complex carbohydrate catabolism in the pathogenesis of invasive streptococci

(2008) Samuel A. Shelburne et al.   TRENDS IN MICROBIOLOGY