Influenza virus nucleoprotein: structure, RNA binding, oligomerization and antiviral drug target

Structure-Based Discovery of the Novel Antiviral Properties of Naproxen against the Nucleoprotein of Influenza A Virus

(2013) Nathalie Lejal et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Nucleozin Targets Cytoplasmic Trafficking of Viral Ribonucleoprotein-Rab11 Complexes in Influenza A Virus Infection

(2013) M. J. Amorim et al.   JOURNAL OF VIROLOGY

The role and assembly mechanism of nucleoprotein in influenza A virus ribonucleoprotein complexes

(2013) Lauren Turrell et al.   Nature Communications

Monomeric Nucleoprotein of Influenza A Virus

(2013) Sylvie Chenavas et al.   PLoS Pathogens

Design, Synthesis, and in Vitro Biological Evaluation of 1H-1,2,3-Triazole-4-carboxamide Derivatives as New Anti-influenza A Agents Targeting Virus Nucleoprotein

(2012) Huimin Cheng et al.   JOURNAL OF MEDICINAL CHEMISTRY

Structural Basis for RNA Binding and Homo-Oligomer Formation by Influenza B Virus Nucleoprotein

(2012) A. K.-L. Ng et al.   JOURNAL OF VIROLOGY

Influenza Polymerase Activity Correlates with the Strength of Interaction between Nucleoprotein and PB2 through the Host-Specific Residue K/E627

(2012) Andy Ka-Leung Ng et al.   PLoS One

The Structure of Native Influenza Virion Ribonucleoproteins

(2012) R. Arranz et al.   SCIENCE

Organization of the Influenza Virus Replication Machinery

(2012) A. Moeller et al.   SCIENCE

Biochemical and Structural Evidence in Support of a Coherent Model for the Formation of the Double-Helical Influenza A Virus Ribonucleoprotein

(2012) Q. Ye et al.   mBio

Mapping the Phosphoproteome of Influenza A and B Viruses by Mass Spectrometry

(2012) Edward C. Hutchinson et al.   PLoS Pathogens

Oligomerization paths of the nucleoprotein of influenza A virus

(2011) B. Tarus et al.   BIOCHIMIE

Nucleoproteins and nucleocapsids of negative-strand RNA viruses

(2011) Rob WH Ruigrok et al.   CURRENT OPINION IN MICROBIOLOGY

The Viral Nucleoprotein Determines Mx Sensitivity of Influenza A Viruses

(2011) P. Zimmermann et al.   JOURNAL OF VIROLOGY

E339...R416 salt bridge of nucleoprotein as a feasible target for influenza virus inhibitors

(2011) Y.-F. Shen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inhibition of influenza virus replication via small molecules that induce the formation of higher-order nucleoprotein oligomers

(2011) S. W. Gerritz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Emerging cellular targets for influenza antiviral agents

(2011) Konstantin H. Müller et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Functional Analysis of the Influenza Virus H5N1 Nucleoprotein Tail Loop Reveals Amino Acids That Are Crucial for Oligomerization and Ribonucleoprotein Activities

(2010) W.-H. Chan et al.   JOURNAL OF VIROLOGY

Identification of influenza A nucleoprotein as an antiviral target

(2010) Richard Y Kao et al.   NATURE BIOTECHNOLOGY

Structures of influenza A proteins and insights into antiviral drug targets

(2010) Kalyan Das et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

High-throughput identification of compounds targeting influenza RNA-dependent RNA polymerase activity

(2010) C.-Y. Su et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Human importin alpha and RNA do not compete for binding to influenza A virus nucleoprotein

(2010) Sébastien Boulo et al.   VIROLOGY

Mutational Analysis of Conserved Amino Acids in the Influenza A Virus Nucleoprotein

(2009) Z. Li et al.   JOURNAL OF VIROLOGY

The Structure of a Biologically Active Influenza Virus Ribonucleoprotein Complex

(2009) Rocío Coloma et al.   PLoS Pathogens

Structure of the influenza virus A H5N1 nucleoprotein: implications for RNA binding, oligomerization, and vaccine design

(2008) Andy Ka-Leung Ng et al.   FASEB JOURNAL